FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968210823> ?p ?o ?g. }

• W1968210823 abstract "Abstract The DNA-binding proteins synthesized by WI-38 cells at specific periods during the cell cycle were chromatographed on calf thymus DNA-cellulose and analyzed by SDS-polyacrylamide gel electrophoresis. The DNA-binding proteins which were predominantly labeled in G 1 had approximate mol wts of 20 000, 30 000 and 68 000. During the S phase, in addition to the G 1 proteins, some large proteins and histones were labeled. Proteins of approx. 45 000 D seemed to be unique to the S period. The profile of DNA-binding proteins synthesized in G 2 is very similar to that of G 1. The labeling of DNA-binding proteins in the early G1 was markedly reduced in the presence of 5 μg/ml of actinomycin D indicating that synthesis of these G 1 proteins is dependent on new transcription. In order to determine the relationship between the DNA-binding proteins prepared from the whole cell sonicates and nuclear proteins, DNA-binding proteins of cytoplasm and nuclear fractions were examined. DNA-binding proteins are found to exist both in nuclear and cytoplasmic fractions of WI-38 cells. Nucleocytoplasmic migration of DNA-binding proteins was also studied by pulse labeling G 1 cells with 3 H-leucine and determining the amount of radioactivity incorporated into cytoplasmic and nuclear DNA-binding protein fractions after chasing for various periods of time. Furthermore, incubation of unlabeled isolated nuclei with the 3 H-DNA-binding proteins in vitro revealed that fractions of these cytoplasmic DNA-binding proteins are transported in nuclei. Present experiments suggest that DNA-binding proteins synthesized in the late G 1 are correlated with the onset of S and that a fraction of DNA-binding proteins synthesized in the cytoplasm migrates into the nuclei." @default.
• W1968210823 created "2016-06-24" @default.
• W1968210823 creator A5018111353 @default.
• W1968210823 creator A5062930600 @default.
• W1968210823 date "1974-02-01" @default.
• W1968210823 modified "2023-09-25" @default.
• W1968210823 title "Synthesis of DNA-binding proteins during the cell cycle of WI-38 cells" @default.
• W1968210823 cites W1493580233 @default.
• W1968210823 cites W1515029606 @default.
• W1968210823 cites W1526421290 @default.
• W1968210823 cites W1676502954 @default.
• W1968210823 cites W1964391265 @default.
• W1968210823 cites W1970647361 @default.
• W1968210823 cites W1977797463 @default.
• W1968210823 cites W1982026809 @default.
• W1968210823 cites W1994253895 @default.
• W1968210823 cites W1997460696 @default.
• W1968210823 cites W2001991689 @default.
• W1968210823 cites W2014346038 @default.
• W1968210823 cites W2017849416 @default.
• W1968210823 cites W2021985719 @default.
• W1968210823 cites W2025904415 @default.
• W1968210823 cites W2030350482 @default.
• W1968210823 cites W2039187149 @default.
• W1968210823 cites W2047330128 @default.
• W1968210823 cites W2062729894 @default.
• W1968210823 cites W2063001690 @default.
• W1968210823 cites W2077260320 @default.
• W1968210823 cites W2087270615 @default.
• W1968210823 cites W2087594882 @default.
• W1968210823 cites W2091702992 @default.
• W1968210823 cites W2092858931 @default.
• W1968210823 cites W2109234804 @default.
• W1968210823 cites W2162158840 @default.
• W1968210823 cites W2277935070 @default.
• W1968210823 cites W2302010320 @default.
• W1968210823 cites W4243616785 @default.
• W1968210823 doi "https://doi.org/10.1016/0014-4827(74)90339-5" @default.
• W1968210823 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4816899" @default.
• W1968210823 hasPublicationYear "1974" @default.
• W1968210823 type Work @default.
• W1968210823 sameAs 1968210823 @default.
• W1968210823 citedByCount "24" @default.
• W1968210823 crossrefType "journal-article" @default.
• W1968210823 hasAuthorship W1968210823A5018111353 @default.
• W1968210823 hasAuthorship W1968210823A5062930600 @default.
• W1968210823 hasConcept C101762097 @default.
• W1968210823 hasConcept C104317684 @default.
• W1968210823 hasConcept C116084860 @default.
• W1968210823 hasConcept C150194340 @default.
• W1968210823 hasConcept C153911025 @default.
• W1968210823 hasConcept C190062978 @default.
• W1968210823 hasConcept C2780114586 @default.
• W1968210823 hasConcept C29512474 @default.
• W1968210823 hasConcept C3662595 @default.
• W1968210823 hasConcept C552990157 @default.
• W1968210823 hasConcept C55493867 @default.
• W1968210823 hasConcept C64927066 @default.
• W1968210823 hasConcept C86339819 @default.
• W1968210823 hasConcept C86803240 @default.
• W1968210823 hasConcept C87026931 @default.
• W1968210823 hasConcept C94966510 @default.
• W1968210823 hasConceptScore W1968210823C101762097 @default.
• W1968210823 hasConceptScore W1968210823C104317684 @default.
• W1968210823 hasConceptScore W1968210823C116084860 @default.
• W1968210823 hasConceptScore W1968210823C150194340 @default.
• W1968210823 hasConceptScore W1968210823C153911025 @default.
• W1968210823 hasConceptScore W1968210823C190062978 @default.
• W1968210823 hasConceptScore W1968210823C2780114586 @default.
• W1968210823 hasConceptScore W1968210823C29512474 @default.
• W1968210823 hasConceptScore W1968210823C3662595 @default.
• W1968210823 hasConceptScore W1968210823C552990157 @default.
• W1968210823 hasConceptScore W1968210823C55493867 @default.
• W1968210823 hasConceptScore W1968210823C64927066 @default.
• W1968210823 hasConceptScore W1968210823C86339819 @default.
• W1968210823 hasConceptScore W1968210823C86803240 @default.
• W1968210823 hasConceptScore W1968210823C87026931 @default.
• W1968210823 hasConceptScore W1968210823C94966510 @default.
• W1968210823 hasLocation W19682108231 @default.
• W1968210823 hasLocation W19682108232 @default.
• W1968210823 hasOpenAccess W1968210823 @default.
• W1968210823 hasPrimaryLocation W19682108231 @default.
• W1968210823 hasRelatedWork W1544463062 @default.
• W1968210823 hasRelatedWork W1982986056 @default.
• W1968210823 hasRelatedWork W2041051130 @default.
• W1968210823 hasRelatedWork W2054608659 @default.
• W1968210823 hasRelatedWork W2055156816 @default.
• W1968210823 hasRelatedWork W2062057385 @default.
• W1968210823 hasRelatedWork W2093620177 @default.
• W1968210823 hasRelatedWork W2132205889 @default.
• W1968210823 hasRelatedWork W2144284013 @default.
• W1968210823 hasRelatedWork W2148333786 @default.
• W1968210823 isParatext "false" @default.
• W1968210823 isRetracted "false" @default.
• W1968210823 magId "1968210823" @default.
• W1968210823 workType "article" @default.