Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968233035> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1968233035 endingPage "495" @default.
- W1968233035 startingPage "491" @default.
- W1968233035 abstract "Elevated plasma levels of inflammation and endothelial dysfunction markers have been reported in patients with hypertrophic cardiomyopathy (HCM). The aim of the current study was to determine whether HCM is associated with enhanced oxidative stress. We enrolled 54 HCM patients with sinus rhythm, including 21 subjects with a left ventricular outflow tract (LVOT) obstruction (gradient >/= 30 mmHg), and 54 age- and sex-matched controls without cardiovascular diseases. Serum levels of 8-isoprostaglandin F(2alpha) (8-iso-PGF(2alpha)), a stable marker of oxidative stress, were determined. Serum 8-iso-PGF(2alpha) levels were elevated in HCM patients compared with controls (35.4 +/- 10.2 vs. 29.9 +/- 9.9 pg/ml, p < 0.001). Patients with obstructive HCM displayed higher 8-iso-PGF(2alpha) levels compared with the non-obstructive HCM subgroup (41.6 +/- 12.7 vs. 31.4 +/- 5.4 pg/ml, p < 0.0001). Both anatomic (mitral-septal distance) and hemodynamic (subaortic gradient) indexes of LVOT obstruction, but not other echocardiographic variables, correlated with 8-iso-PGF(2alpha) levels (r = -0.43; p < 0.05 and r = 0.39; p < 0.05, respectively). This study is the first to show that HCM is characterized by enhanced oxidative stress as evidenced by higher 8-iso-PGF(2alpha), which achieves its highest values in the presence of LVOT obstruction in HCM patients." @default.
- W1968233035 created "2016-06-24" @default.
- W1968233035 creator A5006091397 @default.
- W1968233035 creator A5013080076 @default.
- W1968233035 creator A5015879866 @default.
- W1968233035 creator A5043882797 @default.
- W1968233035 creator A5052251497 @default.
- W1968233035 date "2009-05-01" @default.
- W1968233035 modified "2023-10-11" @default.
- W1968233035 title "Enhanced oxidative stress in hypertrophic cardiomyopathy" @default.
- W1968233035 cites W1508616278 @default.
- W1968233035 cites W1980322984 @default.
- W1968233035 cites W1985889471 @default.
- W1968233035 cites W1986636360 @default.
- W1968233035 cites W1987457816 @default.
- W1968233035 cites W1989057467 @default.
- W1968233035 cites W1998521498 @default.
- W1968233035 cites W2002830624 @default.
- W1968233035 cites W2023723492 @default.
- W1968233035 cites W2064525822 @default.
- W1968233035 cites W2071409082 @default.
- W1968233035 cites W2081849662 @default.
- W1968233035 cites W2102797065 @default.
- W1968233035 cites W2142693924 @default.
- W1968233035 cites W2171466485 @default.
- W1968233035 cites W2316210144 @default.
- W1968233035 doi "https://doi.org/10.1016/s1734-1140(09)70091-x" @default.
- W1968233035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19605948" @default.
- W1968233035 hasPublicationYear "2009" @default.
- W1968233035 type Work @default.
- W1968233035 sameAs 1968233035 @default.
- W1968233035 citedByCount "42" @default.
- W1968233035 countsByYear W19682330352012 @default.
- W1968233035 countsByYear W19682330352013 @default.
- W1968233035 countsByYear W19682330352014 @default.
- W1968233035 countsByYear W19682330352015 @default.
- W1968233035 countsByYear W19682330352016 @default.
- W1968233035 countsByYear W19682330352018 @default.
- W1968233035 countsByYear W19682330352019 @default.
- W1968233035 countsByYear W19682330352020 @default.
- W1968233035 countsByYear W19682330352021 @default.
- W1968233035 countsByYear W19682330352022 @default.
- W1968233035 countsByYear W19682330352023 @default.
- W1968233035 crossrefType "journal-article" @default.
- W1968233035 hasAuthorship W1968233035A5006091397 @default.
- W1968233035 hasAuthorship W1968233035A5013080076 @default.
- W1968233035 hasAuthorship W1968233035A5015879866 @default.
- W1968233035 hasAuthorship W1968233035A5043882797 @default.
- W1968233035 hasAuthorship W1968233035A5052251497 @default.
- W1968233035 hasBestOaLocation W19682330352 @default.
- W1968233035 hasConcept C126322002 @default.
- W1968233035 hasConcept C164705383 @default.
- W1968233035 hasConcept C178853913 @default.
- W1968233035 hasConcept C2775914520 @default.
- W1968233035 hasConcept C2776151105 @default.
- W1968233035 hasConcept C2777361368 @default.
- W1968233035 hasConcept C2778198053 @default.
- W1968233035 hasConcept C2778797674 @default.
- W1968233035 hasConcept C2779161974 @default.
- W1968233035 hasConcept C2780185194 @default.
- W1968233035 hasConcept C71924100 @default.
- W1968233035 hasConceptScore W1968233035C126322002 @default.
- W1968233035 hasConceptScore W1968233035C164705383 @default.
- W1968233035 hasConceptScore W1968233035C178853913 @default.
- W1968233035 hasConceptScore W1968233035C2775914520 @default.
- W1968233035 hasConceptScore W1968233035C2776151105 @default.
- W1968233035 hasConceptScore W1968233035C2777361368 @default.
- W1968233035 hasConceptScore W1968233035C2778198053 @default.
- W1968233035 hasConceptScore W1968233035C2778797674 @default.
- W1968233035 hasConceptScore W1968233035C2779161974 @default.
- W1968233035 hasConceptScore W1968233035C2780185194 @default.
- W1968233035 hasConceptScore W1968233035C71924100 @default.
- W1968233035 hasIssue "3" @default.
- W1968233035 hasLocation W19682330351 @default.
- W1968233035 hasLocation W19682330352 @default.
- W1968233035 hasLocation W19682330353 @default.
- W1968233035 hasOpenAccess W1968233035 @default.
- W1968233035 hasPrimaryLocation W19682330351 @default.
- W1968233035 hasRelatedWork W2005535196 @default.
- W1968233035 hasRelatedWork W2051714653 @default.
- W1968233035 hasRelatedWork W2089178533 @default.
- W1968233035 hasRelatedWork W2099957905 @default.
- W1968233035 hasRelatedWork W2102278394 @default.
- W1968233035 hasRelatedWork W2134992907 @default.
- W1968233035 hasRelatedWork W2421994460 @default.
- W1968233035 hasRelatedWork W2910767765 @default.
- W1968233035 hasRelatedWork W3043744922 @default.
- W1968233035 hasRelatedWork W3112678688 @default.
- W1968233035 hasVolume "61" @default.
- W1968233035 isParatext "false" @default.
- W1968233035 isRetracted "false" @default.
- W1968233035 magId "1968233035" @default.
- W1968233035 workType "article" @default.