FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968261308> ?p ?o ?g. }

• W1968261308 endingPage "7" @default.
• W1968261308 startingPage "1" @default.
• W1968261308 abstract "1. Mechanisms regulating cerebral circulation, including autoregulation of cerebral blood flow (CBF), have been widely investigated. Vasodilators such as nitric oxide, prostacyclin, calcitonin gene-related peptide (CGRP) and K+ channel openers are well known to have important roles in the physiological and pathophysiological control of CBF autoregulation. In the present review, the focus is on the mechanism(s) of altered CBF autoregulation after traumatic brain injury and subarachnoid haemorrhage (SAH) and on the effect of adenovirus-mediated transfer of Cu/Zn superoxide dismutase (SOD)-1 in amelioration of impaired CBF autoregulation. 2. The roles of CGRP and adenosine are particularly emphasized, both being implicated in the autoregulatory vasodilation of the pial artery in response to hypotension. 3. After fluid percussion injury, production of NADPH oxidase-derived superoxide anion and activation of tyrosine kinase links the inhibition of K+ channels to impaired autoregulatory vasodilation in response to acute hypotension and alterations in CBF autoregulation in rat pial artery. 4. Subarachnoid haemorrhage during the acute stage causes an increase in NADPH oxidase-dependent superoxide formation in cerebral vessels in association with activated tyrosine phosphorylation-coupled increased expression of gp91phox mRNA and membrane translocation of Rac protein, thereby resulting in a significant reduction of autoregulatory vasodilation. 5. Fluid percussion injury and SAH-induced overproduction of superoxide anion in cerebral vessels contributes to the impairment of CBF autoregulation and administration of recombinant adenovirus-mediated transfer of the Cu/Zn SOD-1 gene effectively ameliorates the impairment of CBF autoregulation of the pial artery." @default.
• W1968261308 created "2016-06-24" @default.
• W1968261308 creator A5022665853 @default.
• W1968261308 creator A5042047712 @default.
• W1968261308 date "2004-01-01" @default.
• W1968261308 modified "2023-09-25" @default.
• W1968261308 title "Importance of calcitonin gene-related peptide, adenosine and reactive oxygen species in cerebral autoregulation under normal and diseased conditions" @default.
• W1968261308 cites W1679832876 @default.
• W1968261308 cites W1753089048 @default.
• W1968261308 cites W1919291000 @default.
• W1968261308 cites W1983253016 @default.
• W1968261308 cites W1985960247 @default.
• W1968261308 cites W1985965683 @default.
• W1968261308 cites W2003471941 @default.
• W1968261308 cites W2012746436 @default.
• W1968261308 cites W2023643811 @default.
• W1968261308 cites W2030118453 @default.
• W1968261308 cites W2038078887 @default.
• W1968261308 cites W2039523986 @default.
• W1968261308 cites W2051247974 @default.
• W1968261308 cites W2052478404 @default.
• W1968261308 cites W2055947965 @default.
• W1968261308 cites W2058100090 @default.
• W1968261308 cites W2059982861 @default.
• W1968261308 cites W2063774068 @default.
• W1968261308 cites W2067494203 @default.
• W1968261308 cites W2071616677 @default.
• W1968261308 cites W2071969879 @default.
• W1968261308 cites W2072011698 @default.
• W1968261308 cites W2072643276 @default.
• W1968261308 cites W2074772121 @default.
• W1968261308 cites W2084159987 @default.
• W1968261308 cites W2090544950 @default.
• W1968261308 cites W2090749314 @default.
• W1968261308 cites W2107634832 @default.
• W1968261308 cites W2110182057 @default.
• W1968261308 cites W2123619121 @default.
• W1968261308 cites W2124190507 @default.
• W1968261308 cites W2134592756 @default.
• W1968261308 cites W2136590470 @default.
• W1968261308 cites W2143981013 @default.
• W1968261308 cites W2147923929 @default.
• W1968261308 cites W2176190427 @default.
• W1968261308 cites W2464065178 @default.
• W1968261308 cites W4230020738 @default.
• W1968261308 doi "https://doi.org/10.1111/j.1440-1681.2004.03943.x" @default.
• W1968261308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14756677" @default.
• W1968261308 hasPublicationYear "2004" @default.
• W1968261308 type Work @default.
• W1968261308 sameAs 1968261308 @default.
• W1968261308 citedByCount "22" @default.
• W1968261308 countsByYear W19682613082014 @default.
• W1968261308 countsByYear W19682613082015 @default.
• W1968261308 countsByYear W19682613082018 @default.
• W1968261308 countsByYear W19682613082019 @default.
• W1968261308 countsByYear W19682613082020 @default.
• W1968261308 countsByYear W19682613082021 @default.
• W1968261308 crossrefType "journal-article" @default.
• W1968261308 hasAuthorship W1968261308A5022665853 @default.
• W1968261308 hasAuthorship W1968261308A5042047712 @default.
• W1968261308 hasConcept C111774379 @default.
• W1968261308 hasConcept C118303440 @default.
• W1968261308 hasConcept C119671327 @default.
• W1968261308 hasConcept C120770815 @default.
• W1968261308 hasConcept C126322002 @default.
• W1968261308 hasConcept C134018914 @default.
• W1968261308 hasConcept C163170386 @default.
• W1968261308 hasConcept C170493617 @default.
• W1968261308 hasConcept C181199279 @default.
• W1968261308 hasConcept C185592680 @default.
• W1968261308 hasConcept C2776151105 @default.
• W1968261308 hasConcept C2779719074 @default.
• W1968261308 hasConcept C2780795997 @default.
• W1968261308 hasConcept C42219234 @default.
• W1968261308 hasConcept C55493867 @default.
• W1968261308 hasConcept C71924100 @default.
• W1968261308 hasConcept C84359808 @default.
• W1968261308 hasConcept C84393581 @default.
• W1968261308 hasConcept C98274493 @default.
• W1968261308 hasConceptScore W1968261308C111774379 @default.
• W1968261308 hasConceptScore W1968261308C118303440 @default.
• W1968261308 hasConceptScore W1968261308C119671327 @default.
• W1968261308 hasConceptScore W1968261308C120770815 @default.
• W1968261308 hasConceptScore W1968261308C126322002 @default.
• W1968261308 hasConceptScore W1968261308C134018914 @default.
• W1968261308 hasConceptScore W1968261308C163170386 @default.
• W1968261308 hasConceptScore W1968261308C170493617 @default.
• W1968261308 hasConceptScore W1968261308C181199279 @default.
• W1968261308 hasConceptScore W1968261308C185592680 @default.
• W1968261308 hasConceptScore W1968261308C2776151105 @default.
• W1968261308 hasConceptScore W1968261308C2779719074 @default.
• W1968261308 hasConceptScore W1968261308C2780795997 @default.
• W1968261308 hasConceptScore W1968261308C42219234 @default.
• W1968261308 hasConceptScore W1968261308C55493867 @default.
• W1968261308 hasConceptScore W1968261308C71924100 @default.
• W1968261308 hasConceptScore W1968261308C84359808 @default.
• W1968261308 hasConceptScore W1968261308C84393581 @default.
• W1968261308 hasConceptScore W1968261308C98274493 @default.

• next