Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968280274> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1968280274 endingPage "319" @default.
- W1968280274 startingPage "309" @default.
- W1968280274 abstract "The synthesis of poly(ethyleneglycol) (PEG)-lectin conjugates was investigated to provide new reagents for evaluation as biological response modifiers. PEG was activated with 1,1′-carbonyldiimidazole (CDI), followed by conjugation with Ricinus communis I (RCAI) lectin. The resulting conjugates were heterodisperse with respect to molecular weight. Carbohydrate-binding activity was retained. The conjugates were separated by affinity chromatography into fractions differing in apparent carbohydrate-binding affinity. Conjugation of RCAI with PEG4 (mol.wt. 3350) or PEG 6 (mol.wt.8000) appeared to provide less hindrance of the lectin binding site compared to conjugates prepared with PEG 20 (mol.wt. 20 000). Results of free amine assays indicated that higher ratios of PEG to RCAI in conjugates correlated with loss of low-affinity binding and retention of high-affinity binding. The data showed the feasibility of preparing PEG-lectin conjugates for in vivo use." @default.
- W1968280274 created "2016-06-24" @default.
- W1968280274 creator A5013028318 @default.
- W1968280274 creator A5035735152 @default.
- W1968280274 creator A5090175941 @default.
- W1968280274 date "1991-06-01" @default.
- W1968280274 modified "2023-09-23" @default.
- W1968280274 title "Synthesis and carbohydrate-binding activity of poly(ethyl-eneglycol)-Ricinus communis agglutinin I conjugates" @default.
- W1968280274 cites W1771396631 @default.
- W1968280274 cites W1848552725 @default.
- W1968280274 cites W1915881387 @default.
- W1968280274 cites W1960649778 @default.
- W1968280274 cites W1972873729 @default.
- W1968280274 cites W1998642260 @default.
- W1968280274 cites W2007036517 @default.
- W1968280274 cites W2009119064 @default.
- W1968280274 cites W2011561391 @default.
- W1968280274 cites W2011980599 @default.
- W1968280274 cites W2028066309 @default.
- W1968280274 cites W2037434270 @default.
- W1968280274 cites W2041621092 @default.
- W1968280274 cites W2052281430 @default.
- W1968280274 cites W2053416568 @default.
- W1968280274 cites W2057729296 @default.
- W1968280274 cites W2058821461 @default.
- W1968280274 cites W2063044288 @default.
- W1968280274 cites W207971326 @default.
- W1968280274 cites W2081270475 @default.
- W1968280274 cites W2088244278 @default.
- W1968280274 cites W2124983348 @default.
- W1968280274 cites W2162299766 @default.
- W1968280274 doi "https://doi.org/10.1016/s0008-6215(00)90617-7" @default.
- W1968280274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1933945" @default.
- W1968280274 hasPublicationYear "1991" @default.
- W1968280274 type Work @default.
- W1968280274 sameAs 1968280274 @default.
- W1968280274 citedByCount "2" @default.
- W1968280274 crossrefType "journal-article" @default.
- W1968280274 hasAuthorship W1968280274A5013028318 @default.
- W1968280274 hasAuthorship W1968280274A5035735152 @default.
- W1968280274 hasAuthorship W1968280274A5090175941 @default.
- W1968280274 hasConcept C10138342 @default.
- W1968280274 hasConcept C131779359 @default.
- W1968280274 hasConcept C134306372 @default.
- W1968280274 hasConcept C162324750 @default.
- W1968280274 hasConcept C178790620 @default.
- W1968280274 hasConcept C179247698 @default.
- W1968280274 hasConcept C181199279 @default.
- W1968280274 hasConcept C185592680 @default.
- W1968280274 hasConcept C197336794 @default.
- W1968280274 hasConcept C2777127260 @default.
- W1968280274 hasConcept C2778977261 @default.
- W1968280274 hasConcept C2780758401 @default.
- W1968280274 hasConcept C33923547 @default.
- W1968280274 hasConcept C43617362 @default.
- W1968280274 hasConcept C54400483 @default.
- W1968280274 hasConcept C55493867 @default.
- W1968280274 hasConceptScore W1968280274C10138342 @default.
- W1968280274 hasConceptScore W1968280274C131779359 @default.
- W1968280274 hasConceptScore W1968280274C134306372 @default.
- W1968280274 hasConceptScore W1968280274C162324750 @default.
- W1968280274 hasConceptScore W1968280274C178790620 @default.
- W1968280274 hasConceptScore W1968280274C179247698 @default.
- W1968280274 hasConceptScore W1968280274C181199279 @default.
- W1968280274 hasConceptScore W1968280274C185592680 @default.
- W1968280274 hasConceptScore W1968280274C197336794 @default.
- W1968280274 hasConceptScore W1968280274C2777127260 @default.
- W1968280274 hasConceptScore W1968280274C2778977261 @default.
- W1968280274 hasConceptScore W1968280274C2780758401 @default.
- W1968280274 hasConceptScore W1968280274C33923547 @default.
- W1968280274 hasConceptScore W1968280274C43617362 @default.
- W1968280274 hasConceptScore W1968280274C54400483 @default.
- W1968280274 hasConceptScore W1968280274C55493867 @default.
- W1968280274 hasLocation W19682802741 @default.
- W1968280274 hasLocation W19682802742 @default.
- W1968280274 hasOpenAccess W1968280274 @default.
- W1968280274 hasPrimaryLocation W19682802741 @default.
- W1968280274 hasRelatedWork W141148994 @default.
- W1968280274 hasRelatedWork W1968280274 @default.
- W1968280274 hasRelatedWork W2009215244 @default.
- W1968280274 hasRelatedWork W2015200947 @default.
- W1968280274 hasRelatedWork W2016617621 @default.
- W1968280274 hasRelatedWork W2026694381 @default.
- W1968280274 hasRelatedWork W2063777900 @default.
- W1968280274 hasRelatedWork W2258362497 @default.
- W1968280274 hasRelatedWork W3157208478 @default.
- W1968280274 hasRelatedWork W3160461210 @default.
- W1968280274 hasVolume "213" @default.
- W1968280274 isParatext "false" @default.
- W1968280274 isRetracted "false" @default.
- W1968280274 magId "1968280274" @default.
- W1968280274 workType "article" @default.