FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968311523> ?p ?o ?g. }

• W1968311523 endingPage "163" @default.
• W1968311523 startingPage "145" @default.
• W1968311523 abstract "Interest in the interactions between nervous and immune systems involved in both pathological and homeostatic mechanisms of host defence has prompted studies of neuroendocrine immune modulation and cytokine involvement in neuropathologies. In this review we concentrate on a distinct area of homeostatic control of both normal and abnormal host defence activity involving the network of peripheral c-fibre nerve fibres. These nerve fibres have long been recognized by dermatologists and gastroenterologists as key players in abnormal inflammatory processes, such as dermatitis and eczema. However, the involvement of nerves can all too easily be regarded as that of isolated elements in a local phenomenon. On the contrary, it is becoming increasingly clear that neural monitoring of host defence activities takes place, and that involvement of central/spinal mechanisms are crucial in the co-ordination of the adaptive response to host challenge. We describe studies demonstrating neural control of host defence and use the specific examples of bone marrow haemopoiesis and contact sensitivity to highlight the role of direct nerve fibre connections in these activities. We propose a host monitoring system that requires interaction between specialized immune cells and nerve fibres distributed throughout the body and that gives rise to both neural and immune memories of prior challenge. While immunological mechanisms alone may be sufficient for local responsiveness to subsequent challenge, data are discussed that implicate the neural memory in co-ordination of host defence across the body, at distinct sites not served by the same nerve fibres, consistent with central nervous mediation." @default.
• W1968311523 created "2016-06-24" @default.
• W1968311523 creator A5032909017 @default.
• W1968311523 creator A5044559769 @default.
• W1968311523 creator A5073940156 @default.
• W1968311523 date "2005-09-13" @default.
• W1968311523 modified "2023-10-15" @default.
• W1968311523 title "Without nerves, immunology remains incomplete -in vivo veritas" @default.
• W1968311523 cites W111579193 @default.
• W1968311523 cites W132944856 @default.
• W1968311523 cites W1496633211 @default.
• W1968311523 cites W1498564737 @default.
• W1968311523 cites W1499128064 @default.
• W1968311523 cites W1511198581 @default.
• W1968311523 cites W1536099793 @default.
• W1968311523 cites W1542795311 @default.
• W1968311523 cites W1543534068 @default.
• W1968311523 cites W1548316291 @default.
• W1968311523 cites W1549362496 @default.
• W1968311523 cites W1573822995 @default.
• W1968311523 cites W1574175907 @default.
• W1968311523 cites W1575337233 @default.
• W1968311523 cites W1579725574 @default.
• W1968311523 cites W1581243959 @default.
• W1968311523 cites W158221314 @default.
• W1968311523 cites W1582311201 @default.
• W1968311523 cites W1583971934 @default.
• W1968311523 cites W1588310507 @default.
• W1968311523 cites W1593022712 @default.
• W1968311523 cites W1601851819 @default.
• W1968311523 cites W1603024961 @default.
• W1968311523 cites W1604336646 @default.
• W1968311523 cites W1617037549 @default.
• W1968311523 cites W1669491348 @default.
• W1968311523 cites W1767746983 @default.
• W1968311523 cites W1803911072 @default.
• W1968311523 cites W1855852462 @default.
• W1968311523 cites W1877154941 @default.
• W1968311523 cites W1883044208 @default.
• W1968311523 cites W1886661910 @default.
• W1968311523 cites W1923093567 @default.
• W1968311523 cites W1964078902 @default.
• W1968311523 cites W1964156141 @default.
• W1968311523 cites W1965730561 @default.
• W1968311523 cites W1965856324 @default.
• W1968311523 cites W1966400525 @default.
• W1968311523 cites W1967875282 @default.
• W1968311523 cites W1968144318 @default.
• W1968311523 cites W1968736314 @default.
• W1968311523 cites W1969354148 @default.
• W1968311523 cites W1969742709 @default.
• W1968311523 cites W1970092944 @default.
• W1968311523 cites W1970770990 @default.
• W1968311523 cites W1973223056 @default.
• W1968311523 cites W1973355249 @default.
• W1968311523 cites W1973988500 @default.
• W1968311523 cites W1975171976 @default.
• W1968311523 cites W1975745651 @default.
• W1968311523 cites W1976426993 @default.
• W1968311523 cites W1978546851 @default.
• W1968311523 cites W1978641660 @default.
• W1968311523 cites W1980531306 @default.
• W1968311523 cites W1980840326 @default.
• W1968311523 cites W1982151685 @default.
• W1968311523 cites W1982527013 @default.
• W1968311523 cites W1984351379 @default.
• W1968311523 cites W1984971006 @default.
• W1968311523 cites W1990539327 @default.
• W1968311523 cites W1991850077 @default.
• W1968311523 cites W1992315473 @default.
• W1968311523 cites W1993983321 @default.
• W1968311523 cites W1994841962 @default.
• W1968311523 cites W1996311779 @default.
• W1968311523 cites W1997106813 @default.
• W1968311523 cites W1998086688 @default.
• W1968311523 cites W1999929353 @default.
• W1968311523 cites W2000582123 @default.
• W1968311523 cites W2000956334 @default.
• W1968311523 cites W2002611075 @default.
• W1968311523 cites W2003862161 @default.
• W1968311523 cites W2004850241 @default.
• W1968311523 cites W2005409839 @default.
• W1968311523 cites W2005566475 @default.
• W1968311523 cites W2006234449 @default.
• W1968311523 cites W2006372856 @default.
• W1968311523 cites W2007563990 @default.
• W1968311523 cites W2007896110 @default.
• W1968311523 cites W2009188732 @default.
• W1968311523 cites W2010228711 @default.
• W1968311523 cites W2011607277 @default.
• W1968311523 cites W2013058375 @default.
• W1968311523 cites W2014198790 @default.
• W1968311523 cites W2014259329 @default.
• W1968311523 cites W2015666335 @default.
• W1968311523 cites W2018031515 @default.
• W1968311523 cites W2020352730 @default.
• W1968311523 cites W2020830047 @default.
• W1968311523 cites W2023535191 @default.

• next