Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968315617> ?p ?o ?g. }
- W1968315617 abstract "Persistent musculoskeletal pain and psychological sequelae following minor motor vehicle collision (MVC) are common problems with a large economic cost. Prospective studies of pain following MVC have demonstrated that demographic characteristics, including female gender and low education level, and psychological characteristics, including high pre-collision anxiety, are independent predictors of persistent pain. These results have contributed to the psychological and social components of a biopsychosocial model of post-MVC pain pathogenesis, but the biological contributors to the model remain poorly defined. Recent experimental studies indicate that genetic variations in adrenergic system function influence the vulnerability to post-traumatic pain, but no studies have examined the contribution of genetic factors to existing predictive models of vulnerability to persistent pain. The Project CRASH study is a federally supported, multicenter, prospective study designed to determine whether variations in genes affecting synaptic catecholamine levels and alpha and beta adrenergic receptor function augment social and psychological factors in a predictive model of persistent musculoskeletal pain and posttraumatic stress disorder (PTSD) following minor MVC. The Project CRASH study will assess pain, pain interference and PTSD symptoms at 6 weeks, 6 months, and 1 year in approximately 1,000 patients enrolled from 8 Emergency Departments in four states with no-fault accident laws. The results from this study will provide insights into the pathophysiology of persistent pain and PTSD following MVC and may serve to improve the ability of clinicians and researchers to identify individuals at high risk for adverse outcomes following minor MVC." @default.
- W1968315617 created "2016-06-24" @default.
- W1968315617 creator A5008055732 @default.
- W1968315617 creator A5030380244 @default.
- W1968315617 creator A5030862795 @default.
- W1968315617 creator A5032039020 @default.
- W1968315617 creator A5054513055 @default.
- W1968315617 creator A5055323138 @default.
- W1968315617 creator A5056343888 @default.
- W1968315617 creator A5068766594 @default.
- W1968315617 creator A5072960338 @default.
- W1968315617 creator A5080313559 @default.
- W1968315617 creator A5080355594 @default.
- W1968315617 creator A5081377088 @default.
- W1968315617 date "2011-09-26" @default.
- W1968315617 modified "2023-10-17" @default.
- W1968315617 title "Using emergency department-based inception cohorts to determine genetic characteristics associated with long term patient outcomes after motor vehicle collision: Methodology of the CRASH study" @default.
- W1968315617 cites W1515043489 @default.
- W1968315617 cites W1594772576 @default.
- W1968315617 cites W1829325864 @default.
- W1968315617 cites W1966534025 @default.
- W1968315617 cites W1970835675 @default.
- W1968315617 cites W1973176036 @default.
- W1968315617 cites W1978208676 @default.
- W1968315617 cites W1980205604 @default.
- W1968315617 cites W1995236543 @default.
- W1968315617 cites W2004856452 @default.
- W1968315617 cites W2005769638 @default.
- W1968315617 cites W2016432478 @default.
- W1968315617 cites W2020693283 @default.
- W1968315617 cites W2028921193 @default.
- W1968315617 cites W2049595315 @default.
- W1968315617 cites W2066564265 @default.
- W1968315617 cites W2068522487 @default.
- W1968315617 cites W2078536201 @default.
- W1968315617 cites W2095239761 @default.
- W1968315617 cites W2109316022 @default.
- W1968315617 cites W2109423305 @default.
- W1968315617 cites W2110392018 @default.
- W1968315617 cites W2112778345 @default.
- W1968315617 cites W2129249260 @default.
- W1968315617 cites W2131965454 @default.
- W1968315617 cites W2157752701 @default.
- W1968315617 cites W2160662805 @default.
- W1968315617 cites W2172151487 @default.
- W1968315617 doi "https://doi.org/10.1186/1471-227x-11-14" @default.
- W1968315617 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3188467" @default.
- W1968315617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21943293" @default.
- W1968315617 hasPublicationYear "2011" @default.
- W1968315617 type Work @default.
- W1968315617 sameAs 1968315617 @default.
- W1968315617 citedByCount "37" @default.
- W1968315617 countsByYear W19683156172012 @default.
- W1968315617 countsByYear W19683156172013 @default.
- W1968315617 countsByYear W19683156172014 @default.
- W1968315617 countsByYear W19683156172015 @default.
- W1968315617 countsByYear W19683156172016 @default.
- W1968315617 countsByYear W19683156172017 @default.
- W1968315617 countsByYear W19683156172018 @default.
- W1968315617 countsByYear W19683156172019 @default.
- W1968315617 countsByYear W19683156172020 @default.
- W1968315617 countsByYear W19683156172021 @default.
- W1968315617 countsByYear W19683156172022 @default.
- W1968315617 countsByYear W19683156172023 @default.
- W1968315617 crossrefType "journal-article" @default.
- W1968315617 hasAuthorship W1968315617A5008055732 @default.
- W1968315617 hasAuthorship W1968315617A5030380244 @default.
- W1968315617 hasAuthorship W1968315617A5030862795 @default.
- W1968315617 hasAuthorship W1968315617A5032039020 @default.
- W1968315617 hasAuthorship W1968315617A5054513055 @default.
- W1968315617 hasAuthorship W1968315617A5055323138 @default.
- W1968315617 hasAuthorship W1968315617A5056343888 @default.
- W1968315617 hasAuthorship W1968315617A5068766594 @default.
- W1968315617 hasAuthorship W1968315617A5072960338 @default.
- W1968315617 hasAuthorship W1968315617A5080313559 @default.
- W1968315617 hasAuthorship W1968315617A5080355594 @default.
- W1968315617 hasAuthorship W1968315617A5081377088 @default.
- W1968315617 hasBestOaLocation W19683156171 @default.
- W1968315617 hasConcept C118552586 @default.
- W1968315617 hasConcept C126322002 @default.
- W1968315617 hasConcept C137886200 @default.
- W1968315617 hasConcept C183469790 @default.
- W1968315617 hasConcept C1862650 @default.
- W1968315617 hasConcept C188816634 @default.
- W1968315617 hasConcept C199360897 @default.
- W1968315617 hasConcept C2780724011 @default.
- W1968315617 hasConcept C41008148 @default.
- W1968315617 hasConcept C558461103 @default.
- W1968315617 hasConcept C71924100 @default.
- W1968315617 hasConceptScore W1968315617C118552586 @default.
- W1968315617 hasConceptScore W1968315617C126322002 @default.
- W1968315617 hasConceptScore W1968315617C137886200 @default.
- W1968315617 hasConceptScore W1968315617C183469790 @default.
- W1968315617 hasConceptScore W1968315617C1862650 @default.
- W1968315617 hasConceptScore W1968315617C188816634 @default.
- W1968315617 hasConceptScore W1968315617C199360897 @default.
- W1968315617 hasConceptScore W1968315617C2780724011 @default.
- W1968315617 hasConceptScore W1968315617C41008148 @default.
- W1968315617 hasConceptScore W1968315617C558461103 @default.
- W1968315617 hasConceptScore W1968315617C71924100 @default.