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- W1968325378 abstract "Glucose pretreatment is known to accentuate the pH difference between most normal tissues and neoplastic tissues. Certain alkylating agents should exert a greater cytotoxic effect in regions of lower pH. This communication reports on the effect of glucose pretreatment on the carcinostatic effect in Walker tumour bearing rats and the toxic effect in normal rats of some aromatic nitrogen mustards, two epoxides, nor-HN2, and triethylenemelamine. Only in the case of triethylenemelamine was a significant increase in the therapeutic index demonstrated." @default.
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- W1968325378 date "1964-03-01" @default.
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- W1968325378 title "The effect of glucose pretreatment on the carcinostatic and toxic activities of some alkylating agents" @default.
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- W1968325378 doi "https://doi.org/10.1016/0006-2952(64)90158-3" @default.
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