Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968335909> ?p ?o ?g. }
- W1968335909 endingPage "20987" @default.
- W1968335909 startingPage "20982" @default.
- W1968335909 abstract "Alternative patterns of neural activity drive different rhythmic locomotory patterns in both invertebrates and mammals. The neuro-molecular mechanisms responsible for the expression of rhythmic behavioral patterns are poorly understood. Here we show that Caenorhabditis elegans switches between distinct forms of locomotion, or crawling versus swimming, when transitioning between solid and liquid environments. These forms of locomotion are distinguished by distinct kinematics and different underlying patterns of neuromuscular activity, as determined by in vivo calcium imaging. The expression of swimming versus crawling rhythms is regulated by sensory input. In a screen for mutants that are defective in transitioning between crawl and swim behavior, we identified unc-79 and unc-80 , two mutants known to be defective in NCA ion channel stabilization. Genetic and behavioral analyses suggest that the NCA channels enable the transition to rapid rhythmic behaviors in C. elegans. unc-79 , unc-80 , and the NCA channels represent a conserved set of genes critical for behavioral pattern generation." @default.
- W1968335909 created "2016-06-24" @default.
- W1968335909 creator A5018478508 @default.
- W1968335909 creator A5019992105 @default.
- W1968335909 creator A5059129645 @default.
- W1968335909 creator A5071752372 @default.
- W1968335909 creator A5082865846 @default.
- W1968335909 creator A5089748442 @default.
- W1968335909 date "2008-12-30" @default.
- W1968335909 modified "2023-10-10" @default.
- W1968335909 title "Genetic analysis of crawling and swimming locomotory patterns in <i>C. elegans</i>" @default.
- W1968335909 cites W1561619916 @default.
- W1968335909 cites W1824021067 @default.
- W1968335909 cites W1944127002 @default.
- W1968335909 cites W1964817556 @default.
- W1968335909 cites W1968923150 @default.
- W1968335909 cites W1974398081 @default.
- W1968335909 cites W1977922844 @default.
- W1968335909 cites W1984081494 @default.
- W1968335909 cites W1998717162 @default.
- W1968335909 cites W2001047941 @default.
- W1968335909 cites W2013257429 @default.
- W1968335909 cites W2016956534 @default.
- W1968335909 cites W2017728979 @default.
- W1968335909 cites W2036786576 @default.
- W1968335909 cites W2049974379 @default.
- W1968335909 cites W2054316680 @default.
- W1968335909 cites W2062849434 @default.
- W1968335909 cites W2064280886 @default.
- W1968335909 cites W2073612535 @default.
- W1968335909 cites W2101822309 @default.
- W1968335909 cites W2108000512 @default.
- W1968335909 cites W2114343956 @default.
- W1968335909 cites W2115682148 @default.
- W1968335909 cites W2118128753 @default.
- W1968335909 cites W2119515379 @default.
- W1968335909 cites W2122107405 @default.
- W1968335909 cites W2123491442 @default.
- W1968335909 cites W2123976402 @default.
- W1968335909 cites W2144420636 @default.
- W1968335909 cites W2150608129 @default.
- W1968335909 cites W2157851792 @default.
- W1968335909 doi "https://doi.org/10.1073/pnas.0810359105" @default.
- W1968335909 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2634943" @default.
- W1968335909 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19074276" @default.
- W1968335909 hasPublicationYear "2008" @default.
- W1968335909 type Work @default.
- W1968335909 sameAs 1968335909 @default.
- W1968335909 citedByCount "242" @default.
- W1968335909 countsByYear W19683359092012 @default.
- W1968335909 countsByYear W19683359092013 @default.
- W1968335909 countsByYear W19683359092014 @default.
- W1968335909 countsByYear W19683359092015 @default.
- W1968335909 countsByYear W19683359092016 @default.
- W1968335909 countsByYear W19683359092017 @default.
- W1968335909 countsByYear W19683359092018 @default.
- W1968335909 countsByYear W19683359092019 @default.
- W1968335909 countsByYear W19683359092020 @default.
- W1968335909 countsByYear W19683359092021 @default.
- W1968335909 countsByYear W19683359092022 @default.
- W1968335909 countsByYear W19683359092023 @default.
- W1968335909 crossrefType "journal-article" @default.
- W1968335909 hasAuthorship W1968335909A5018478508 @default.
- W1968335909 hasAuthorship W1968335909A5019992105 @default.
- W1968335909 hasAuthorship W1968335909A5059129645 @default.
- W1968335909 hasAuthorship W1968335909A5071752372 @default.
- W1968335909 hasAuthorship W1968335909A5082865846 @default.
- W1968335909 hasAuthorship W1968335909A5089748442 @default.
- W1968335909 hasBestOaLocation W19683359092 @default.
- W1968335909 hasConcept C100368936 @default.
- W1968335909 hasConcept C104317684 @default.
- W1968335909 hasConcept C105702510 @default.
- W1968335909 hasConcept C107038049 @default.
- W1968335909 hasConcept C115903868 @default.
- W1968335909 hasConcept C135343436 @default.
- W1968335909 hasConcept C138885662 @default.
- W1968335909 hasConcept C169760540 @default.
- W1968335909 hasConcept C2778944004 @default.
- W1968335909 hasConcept C41008148 @default.
- W1968335909 hasConcept C54355233 @default.
- W1968335909 hasConcept C83804111 @default.
- W1968335909 hasConcept C86803240 @default.
- W1968335909 hasConceptScore W1968335909C100368936 @default.
- W1968335909 hasConceptScore W1968335909C104317684 @default.
- W1968335909 hasConceptScore W1968335909C105702510 @default.
- W1968335909 hasConceptScore W1968335909C107038049 @default.
- W1968335909 hasConceptScore W1968335909C115903868 @default.
- W1968335909 hasConceptScore W1968335909C135343436 @default.
- W1968335909 hasConceptScore W1968335909C138885662 @default.
- W1968335909 hasConceptScore W1968335909C169760540 @default.
- W1968335909 hasConceptScore W1968335909C2778944004 @default.
- W1968335909 hasConceptScore W1968335909C41008148 @default.
- W1968335909 hasConceptScore W1968335909C54355233 @default.
- W1968335909 hasConceptScore W1968335909C83804111 @default.
- W1968335909 hasConceptScore W1968335909C86803240 @default.
- W1968335909 hasIssue "52" @default.
- W1968335909 hasLocation W19683359091 @default.
- W1968335909 hasLocation W19683359092 @default.