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- W1968374417 abstract "Venous blood T cell phenotypes were analysed with monoclonal antibodies after 11 allogeneic and 17 autologous bone marrow transplants. In seven cases studied in the early regenerative period, cells with a thymocyte phenotype were present in the blood. In the large majority of patients treated with both allografts and autografts there was an imbalance of phenotypic 'helper' and 'suppressor' T cell subsets with initially a relative and later an absolute increase of 'suppressor' T cells. This imbalance was still present at over 250 d in eight out nine cases. Suppressor T cells bearing HLA-Dr antigens were abundant in one case of fatal GVHD but not in another, and were also increased following two autografts. It is concluded that T cell phenotyping is not of diagnostic value in sick patients following bone marrow transplantation when graft-versus-host disease is suspected." @default.
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- W1968374417 date "1983-03-01" @default.
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- W1968374417 title "T cell regeneration after allogeneic and autologous bone marrow transplantation" @default.
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- W1968374417 doi "https://doi.org/10.1111/j.1365-2141.1983.tb02046.x" @default.
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