Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968391454> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1968391454 endingPage "561" @default.
- W1968391454 startingPage "556" @default.
- W1968391454 abstract "We studied 31 children with systemic lupus erythematosus (SLE) and 108 first-degree relatives of the children to determine if HLA type, familial relationship to patient, or gender influenced the familial aggregation of SLE and the serologic and serum complement abnormalities associated with SLE. There were no significant relationships between the presence of antinuclear antibodies (ANA), antilymphocyte antibodies (ALA), or circulating immune complexes. Furthermore, there was no correlation between the occurrence of ANA, ALA, or circulating immune complexes with HLA type or relationship to patient. Both ANA and ALA were associated with a reduction in the mean serum C4 level, without a corresponding reduction in mean serum C3 or CH50. The reduction in mean serum C4 level with ALA occurred without regard to the subject's relationship to the patient, but the reduction in mean serum C4 level with ANA was significant only among the sisters. Because of these data, it seems that the sisters of patients with SLE are more likely than other relatives to have activation of the complement system in association with serologic abnormalities. Those sisters with ANA and ALA had the greatest amount of complement activation and may be the relatives at greatest risk for the subsequent development of SLE." @default.
- W1968391454 created "2016-06-24" @default.
- W1968391454 creator A5003276552 @default.
- W1968391454 creator A5028784441 @default.
- W1968391454 creator A5038590620 @default.
- W1968391454 creator A5054330574 @default.
- W1968391454 date "1982-05-01" @default.
- W1968391454 modified "2023-09-27" @default.
- W1968391454 title "The association of antinuclear antibodies, antilymphocyte antibodies, and c4 activation among the relatives of children with systemic lupus erythematosus. preferential activation of complement in sisters" @default.
- W1968391454 cites W1978258821 @default.
- W1968391454 cites W1981515909 @default.
- W1968391454 cites W1983248778 @default.
- W1968391454 cites W1986603574 @default.
- W1968391454 cites W2011203524 @default.
- W1968391454 cites W2011863032 @default.
- W1968391454 cites W2017859096 @default.
- W1968391454 cites W2074684031 @default.
- W1968391454 cites W2100736486 @default.
- W1968391454 cites W2106741681 @default.
- W1968391454 cites W2127145766 @default.
- W1968391454 cites W2313472509 @default.
- W1968391454 cites W2403607094 @default.
- W1968391454 cites W4229492405 @default.
- W1968391454 doi "https://doi.org/10.1002/art.1780250510" @default.
- W1968391454 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6979340" @default.
- W1968391454 hasPublicationYear "1982" @default.
- W1968391454 type Work @default.
- W1968391454 sameAs 1968391454 @default.
- W1968391454 citedByCount "22" @default.
- W1968391454 countsByYear W19683914542021 @default.
- W1968391454 crossrefType "journal-article" @default.
- W1968391454 hasAuthorship W1968391454A5003276552 @default.
- W1968391454 hasAuthorship W1968391454A5028784441 @default.
- W1968391454 hasAuthorship W1968391454A5038590620 @default.
- W1968391454 hasAuthorship W1968391454A5054330574 @default.
- W1968391454 hasBestOaLocation W19683914541 @default.
- W1968391454 hasConcept C111684460 @default.
- W1968391454 hasConcept C126322002 @default.
- W1968391454 hasConcept C149443304 @default.
- W1968391454 hasConcept C159654299 @default.
- W1968391454 hasConcept C163764329 @default.
- W1968391454 hasConcept C203014093 @default.
- W1968391454 hasConcept C2776912625 @default.
- W1968391454 hasConcept C2779134260 @default.
- W1968391454 hasConcept C2779862289 @default.
- W1968391454 hasConcept C2781179581 @default.
- W1968391454 hasConcept C45189115 @default.
- W1968391454 hasConcept C71924100 @default.
- W1968391454 hasConcept C8891405 @default.
- W1968391454 hasConceptScore W1968391454C111684460 @default.
- W1968391454 hasConceptScore W1968391454C126322002 @default.
- W1968391454 hasConceptScore W1968391454C149443304 @default.
- W1968391454 hasConceptScore W1968391454C159654299 @default.
- W1968391454 hasConceptScore W1968391454C163764329 @default.
- W1968391454 hasConceptScore W1968391454C203014093 @default.
- W1968391454 hasConceptScore W1968391454C2776912625 @default.
- W1968391454 hasConceptScore W1968391454C2779134260 @default.
- W1968391454 hasConceptScore W1968391454C2779862289 @default.
- W1968391454 hasConceptScore W1968391454C2781179581 @default.
- W1968391454 hasConceptScore W1968391454C45189115 @default.
- W1968391454 hasConceptScore W1968391454C71924100 @default.
- W1968391454 hasConceptScore W1968391454C8891405 @default.
- W1968391454 hasIssue "5" @default.
- W1968391454 hasLocation W19683914541 @default.
- W1968391454 hasLocation W19683914542 @default.
- W1968391454 hasOpenAccess W1968391454 @default.
- W1968391454 hasPrimaryLocation W19683914541 @default.
- W1968391454 hasRelatedWork W177744588 @default.
- W1968391454 hasRelatedWork W191183980 @default.
- W1968391454 hasRelatedWork W1983299570 @default.
- W1968391454 hasRelatedWork W2038881412 @default.
- W1968391454 hasRelatedWork W2051207147 @default.
- W1968391454 hasRelatedWork W2083220074 @default.
- W1968391454 hasRelatedWork W2086017381 @default.
- W1968391454 hasRelatedWork W2428508182 @default.
- W1968391454 hasRelatedWork W2472498312 @default.
- W1968391454 hasRelatedWork W3048051248 @default.
- W1968391454 hasVolume "25" @default.
- W1968391454 isParatext "false" @default.
- W1968391454 isRetracted "false" @default.
- W1968391454 magId "1968391454" @default.
- W1968391454 workType "article" @default.