FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968392620> ?p ?o ?g. }

• W1968392620 abstract "Hemorheological factors play an important role in the pathomechanism of ischemic cerebrovascular disorders. Abnormal rheological conditions in patients with chronic cerebrovascular disease predispose for recurrent strokes. Vinpocetine (VP), a synthetic ethyl esther of apovincamine, has successfully been used in the treatment of cerebrovascular diseases, in part because of its favourable rheological effects.The study investigates the hemorheological changes in 40 patients in the chronic stage of ischemic cardiovascular disease after administration of vinpocetine. All patients received a high dose of intravenous VP in doses gradually increased to l mg/kg/day. In addition, 20 patients (mean age: 61+/-8 years) received 30 mg VP orally for 3 months. The other 20 patients (mean age: 59+/-6 years), who received placebo tablets, served as controls. Hemorheological parameters (hematocrit, plasma fibrinogen, whole blood viscosity, red blood cell aggregation and deformability) were evaluated at 1 and 3 months.The high-dose parenteral VP significantly decreased red blood cell aggregation, plasma and whole blood viscosity (p < 0.05) compared to the initial values. In patients with additional oral treatment, plasma and whole blood viscosities were significantly lower compared to the placebo patients at 3 months (p < 0.05).Our results confirmed the beneficial rheological effects of high-dose parenteral VP (partially caused by hemodilution) observed previously, and also warrant its long-term oral admission to maintain the beneficial rheological changes." @default.
• W1968392620 created "2016-06-24" @default.
• W1968392620 creator A5013214539 @default.
• W1968392620 creator A5025142343 @default.
• W1968392620 creator A5028627822 @default.
• W1968392620 creator A5033935967 @default.
• W1968392620 creator A5043415555 @default.
• W1968392620 creator A5060660547 @default.
• W1968392620 creator A5066423655 @default.
• W1968392620 date "2009-03-01" @default.
• W1968392620 modified "2023-09-26" @default.
• W1968392620 title "Effect of parenteral or oral vinpocetine on the hemorheological parameters of patients with chronic cerebrovascular diseases" @default.
• W1968392620 cites W1024735895 @default.
• W1968392620 cites W1967809023 @default.
• W1968392620 cites W1973405380 @default.
• W1968392620 cites W1978039741 @default.
• W1968392620 cites W1992827710 @default.
• W1968392620 cites W1997448265 @default.
• W1968392620 cites W2011579508 @default.
• W1968392620 cites W2019631998 @default.
• W1968392620 cites W2027084895 @default.
• W1968392620 cites W2031411680 @default.
• W1968392620 cites W2044332835 @default.
• W1968392620 cites W2046227577 @default.
• W1968392620 cites W2056231808 @default.
• W1968392620 cites W2060884386 @default.
• W1968392620 cites W2064013003 @default.
• W1968392620 cites W2077536041 @default.
• W1968392620 cites W2085746707 @default.
• W1968392620 cites W2088409402 @default.
• W1968392620 cites W2091093079 @default.
• W1968392620 cites W2103915008 @default.
• W1968392620 cites W2119310464 @default.
• W1968392620 cites W2232910593 @default.
• W1968392620 cites W2269764428 @default.
• W1968392620 cites W2326697059 @default.
• W1968392620 cites W2331267590 @default.
• W1968392620 cites W2401259328 @default.
• W1968392620 cites W2401608642 @default.
• W1968392620 cites W2407273944 @default.
• W1968392620 cites W295220161 @default.
• W1968392620 cites W3142350493 @default.
• W1968392620 cites W66376857 @default.
• W1968392620 doi "https://doi.org/10.1016/j.phymed.2008.10.014" @default.
• W1968392620 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19135345" @default.
• W1968392620 hasPublicationYear "2009" @default.
• W1968392620 type Work @default.
• W1968392620 sameAs 1968392620 @default.
• W1968392620 citedByCount "10" @default.
• W1968392620 countsByYear W19683926202012 @default.
• W1968392620 countsByYear W19683926202014 @default.
• W1968392620 countsByYear W19683926202017 @default.
• W1968392620 countsByYear W19683926202018 @default.
• W1968392620 countsByYear W19683926202021 @default.
• W1968392620 countsByYear W19683926202022 @default.
• W1968392620 crossrefType "journal-article" @default.
• W1968392620 hasAuthorship W1968392620A5013214539 @default.
• W1968392620 hasAuthorship W1968392620A5025142343 @default.
• W1968392620 hasAuthorship W1968392620A5028627822 @default.
• W1968392620 hasAuthorship W1968392620A5033935967 @default.
• W1968392620 hasAuthorship W1968392620A5043415555 @default.
• W1968392620 hasAuthorship W1968392620A5060660547 @default.
• W1968392620 hasAuthorship W1968392620A5066423655 @default.
• W1968392620 hasConcept C126322002 @default.
• W1968392620 hasConcept C142724271 @default.
• W1968392620 hasConcept C1621761 @default.
• W1968392620 hasConcept C204787440 @default.
• W1968392620 hasConcept C27081682 @default.
• W1968392620 hasConcept C2777426075 @default.
• W1968392620 hasConcept C2778788455 @default.
• W1968392620 hasConcept C2779036427 @default.
• W1968392620 hasConcept C2780959883 @default.
• W1968392620 hasConcept C2994203641 @default.
• W1968392620 hasConcept C42219234 @default.
• W1968392620 hasConcept C71924100 @default.
• W1968392620 hasConcept C78520924 @default.
• W1968392620 hasConcept C90924648 @default.
• W1968392620 hasConcept C98274493 @default.
• W1968392620 hasConceptScore W1968392620C126322002 @default.
• W1968392620 hasConceptScore W1968392620C142724271 @default.
• W1968392620 hasConceptScore W1968392620C1621761 @default.
• W1968392620 hasConceptScore W1968392620C204787440 @default.
• W1968392620 hasConceptScore W1968392620C27081682 @default.
• W1968392620 hasConceptScore W1968392620C2777426075 @default.
• W1968392620 hasConceptScore W1968392620C2778788455 @default.
• W1968392620 hasConceptScore W1968392620C2779036427 @default.
• W1968392620 hasConceptScore W1968392620C2780959883 @default.
• W1968392620 hasConceptScore W1968392620C2994203641 @default.
• W1968392620 hasConceptScore W1968392620C42219234 @default.
• W1968392620 hasConceptScore W1968392620C71924100 @default.
• W1968392620 hasConceptScore W1968392620C78520924 @default.
• W1968392620 hasConceptScore W1968392620C90924648 @default.
• W1968392620 hasConceptScore W1968392620C98274493 @default.
• W1968392620 hasLocation W19683926201 @default.
• W1968392620 hasLocation W19683926202 @default.
• W1968392620 hasOpenAccess W1968392620 @default.
• W1968392620 hasPrimaryLocation W19683926201 @default.
• W1968392620 hasRelatedWork W1972899588 @default.
• W1968392620 hasRelatedWork W1988800332 @default.
• W1968392620 hasRelatedWork W199962460 @default.

• next