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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968410906> ?p ?o ?g. }

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• W1968410906 startingPage "1606" @default.
• W1968410906 abstract "In wild-type Drosophila, the period protein (PER) is found in nuclei of the eyes and brain, and PER immunoreactivity oscillates with a circadian rhythm. The studies described here indicate that the nuclear localization of PER is blocked by timeless (tim), a second chromosome mutation that, like per null mutations, abolishes circadian rhythms. PER fusion proteins without a conserved domain (PAS) and some flanking sequences are nuclear in tim mutants. This suggests that a segment of PER inhibits nuclear localization in tim mutants. The tim gene may have a role in establishing rhythms of PER abundance and nuclear localization in wild-type flies." @default.
• W1968410906 created "2016-06-24" @default.
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• W1968410906 date "1994-03-18" @default.
• W1968410906 modified "2023-10-15" @default.
• W1968410906 title "Block in Nuclear Localization of <i>period</i> Protein by a Second Clock Mutation, <i>timeless</i>" @default.
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• W1968410906 doi "https://doi.org/10.1126/science.8128247" @default.
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