Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968447670> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W1968447670 abstract "For over a century, investigators have sought to define the mechanisms responsible for exercise intolerance in heart failure. At the outset, this mission appeared a simple one. Exertional dyspnea was attributed to exercise-induced increases in pulmonary wedge pressure. Exertional fatigue was attributed to an inadequate cardiac output. Over the past decade, however, it has become clear that the link between cardiac dysfunction and exertional symptoms in heart failure is far more complex. This understanding has led investigators to explore novel treatment options in heart failure. In this issue of Circulation , Mancini and coworkers describe one such new treatment option: selective respiratory muscle training. At first glance, respiratory muscle training would appear of little value since it targets the skeletal muscle rather than the circulatory system. However, recent observations increasingly suggest that abnormalities of the skeletal muscle system are important contributors to exertional symptoms in patients with heart failure. Indeed, there is growing evidence that the sensations of exertional fatigue and dyspnea are linked, in part, via the skeletal muscle system. The first evidence that noncirculatory factors contribute to exertional symptoms in heart failure came from observations that acutely altering hemodynamic parameters did not alter exertional symptoms. The traditional presumption that dyspnea is caused by elevated intrapulmonary pressures was tested by measuring symptomatic and ventilatory responses to exercise before and after pharmacologic manipulation of the pulmonary wedge pressure; excessive ventilatory levels during exercise have been viewed as a hallmark of lung dysfunction during exercise. Acute reductions …" @default.
- W1968447670 created "2016-06-24" @default.
- W1968447670 creator A5022482703 @default.
- W1968447670 date "1995-01-15" @default.
- W1968447670 modified "2023-09-23" @default.
- W1968447670 title "Exercise Intolerance in Heart Failure" @default.
- W1968447670 cites W2017173129 @default.
- W1968447670 cites W2037457417 @default.
- W1968447670 cites W2037792892 @default.
- W1968447670 cites W2040889700 @default.
- W1968447670 cites W2061074878 @default.
- W1968447670 cites W2073728250 @default.
- W1968447670 cites W2109965174 @default.
- W1968447670 cites W2170506074 @default.
- W1968447670 doi "https://doi.org/10.1161/01.cir.91.2.559" @default.
- W1968447670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7805264" @default.
- W1968447670 hasPublicationYear "1995" @default.
- W1968447670 type Work @default.
- W1968447670 sameAs 1968447670 @default.
- W1968447670 citedByCount "56" @default.
- W1968447670 countsByYear W19684476702012 @default.
- W1968447670 countsByYear W19684476702013 @default.
- W1968447670 countsByYear W19684476702014 @default.
- W1968447670 countsByYear W19684476702015 @default.
- W1968447670 countsByYear W19684476702016 @default.
- W1968447670 countsByYear W19684476702019 @default.
- W1968447670 countsByYear W19684476702020 @default.
- W1968447670 countsByYear W19684476702021 @default.
- W1968447670 crossrefType "journal-article" @default.
- W1968447670 hasAuthorship W1968447670A5022482703 @default.
- W1968447670 hasConcept C126322002 @default.
- W1968447670 hasConcept C139940330 @default.
- W1968447670 hasConcept C164705383 @default.
- W1968447670 hasConcept C178853913 @default.
- W1968447670 hasConcept C2777321227 @default.
- W1968447670 hasConcept C2778198053 @default.
- W1968447670 hasConcept C2779959927 @default.
- W1968447670 hasConcept C2910066949 @default.
- W1968447670 hasConcept C71924100 @default.
- W1968447670 hasConceptScore W1968447670C126322002 @default.
- W1968447670 hasConceptScore W1968447670C139940330 @default.
- W1968447670 hasConceptScore W1968447670C164705383 @default.
- W1968447670 hasConceptScore W1968447670C178853913 @default.
- W1968447670 hasConceptScore W1968447670C2777321227 @default.
- W1968447670 hasConceptScore W1968447670C2778198053 @default.
- W1968447670 hasConceptScore W1968447670C2779959927 @default.
- W1968447670 hasConceptScore W1968447670C2910066949 @default.
- W1968447670 hasConceptScore W1968447670C71924100 @default.
- W1968447670 hasLocation W19684476701 @default.
- W1968447670 hasLocation W19684476702 @default.
- W1968447670 hasOpenAccess W1968447670 @default.
- W1968447670 hasPrimaryLocation W19684476701 @default.
- W1968447670 hasRelatedWork W1972656835 @default.
- W1968447670 hasRelatedWork W2003158566 @default.
- W1968447670 hasRelatedWork W2051712573 @default.
- W1968447670 hasRelatedWork W2061508526 @default.
- W1968447670 hasRelatedWork W2107400784 @default.
- W1968447670 hasRelatedWork W2167244631 @default.
- W1968447670 hasRelatedWork W2328354663 @default.
- W1968447670 hasRelatedWork W2349587018 @default.
- W1968447670 hasRelatedWork W2363366439 @default.
- W1968447670 hasRelatedWork W2375703560 @default.
- W1968447670 isParatext "false" @default.
- W1968447670 isRetracted "false" @default.
- W1968447670 magId "1968447670" @default.
- W1968447670 workType "article" @default.