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- W1968449050 abstract "Twenty‐four calves were immunised four times with gE‐deleted infectious bovine rhinotracheitis marker vaccines before being challenged with small doses of wild‐type bovine herpesvirus type 1 (BHV‐1). The repeated vaccinations induced strong immunity that prevented detectable virus replication and gE‐seroconversion after the challenge infection in most of the calves. The hypervaccinated calves that shed virus after the challenge infection showed no delay in gE‐seroconversion compared with unvaccinated control calves. Using a sensitive nested PCR, BHV‐1 gE sequences could be detected in the trigeminal ganglia of several of the gE‐seronegative, challenge‐infected calves, possibly indicating the presence of wild‐type BHV‐1 DNA." @default.
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- W1968449050 date "2004-10-01" @default.
- W1968449050 modified "2023-09-24" @default.
- W1968449050 title "Effects of hypervaccination with bovine herpesvirus type 1 gE-deleted marker vaccines on the serological response and virological status of calves challenged with wild-type virus" @default.
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- W1968449050 doi "https://doi.org/10.1136/vr.155.18.553" @default.
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