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- W1968571223 abstract "Hippuristanol is a natural product that has recently been shown to inhibit eukaryotic translation initiation and tumor cell proliferation. To investigate the structure and activity relationship of hippuristanol, we synthesized a series of analogs by expanding the size of its F ring and determined their effects on the proliferation of cancer cell lines. All changes to the F-ring of hippuristanol resulted in 3-fold to >100-fold decrease in activity." @default.
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- W1968571223 date "2010-05-01" @default.
- W1968571223 modified "2023-10-16" @default.
- W1968571223 title "Structural and stereochemical requirements of the spiroketal group of hippuristanol for antiproliferative activity" @default.
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- W1968571223 doi "https://doi.org/10.1016/j.bmcl.2010.03.093" @default.
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