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• W1968571725 abstract "Editorial Notes1 July 1971Problems in the Serodiagnosis of TuberculosisB. B. DIENA, PH.D., M.V.D.B. B. DIENA, PH.D., M.V.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-75-1-132 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTuberculosis mortality and morbidity have been impressively reduced by chemotherapy, but in recent years there has been a resurgence of new cases of tuberculosis. Reservoirs of tuberculosis infection are escaping detection because of the inadequacy of mass roentgenography and tuberculin testing. Omran and Deuschule (1), in a controlled study, found an 18% failure rate in the detection of tuberculosis by these methods. Futhermore, tuberculin sensitivity does not equate with active tuberculosis and is of little value after Bacillus Calmette-Guérin (BCG) vaccination. For these reasons, many investigators have tried to develop a serological method for the diagnosis of mycobacterial infections, and...References1. OMRANDEUSCHULE AK: A controlled evaluation of a selective method of tuberculosis case finding. A study performed in a Navajo community. Amer Rev Resp Dis 91: 215-224, 1965 MedlineGoogle Scholar2. MIDDLEBROOKDUBOS GR: Specific serum agglutination of erythrocytes sensitized with extracts of tubercle bacilli. J Exp Med 8:521-528, 1948 CrossrefGoogle Scholar3. DOAN C: Diagnostic significance of precipitin test with Anderson phosphatide fractions from human, bovine and avian tubercle bacilli. Proc Soc Exp Biol Med 26:672-679, 1929 CrossrefGoogle Scholar4. WOOLEY J: Tuberculo-complement fixation, in Laboratory Diagnosis and Experimental Methods in Tuberculosis, edited by WILLIS HS. Charles C Thomas, Publisher, Springfield, Ill., 1928 Google Scholar5. PARLETTYOUMANSREHR RGC: The detection of antibodies in the serum of tuberculous patients by an agar double diffusion precipitation technique. Amer Rev Tuberc Pulmonary Dis 77:462-472, 1958 Google Scholar6. TAKAHASHI Y: Specific serum agglutination of kaolin particles sensitized with tubercle phosphatide and its clinical evaluation as a serodiagnostic test for tuberculosis. Amer Rev Resp Dis 85:708-719, 1962 MedlineGoogle Scholar7. WALLACEDIENAGREENBERG RBL: A study of tuberculosis antibodies by bentonite flocculation. Canad Med Ass J 94:947-950, 1966 MedlineGoogle Scholar8. PARLETT R: The present status of the sero-diagnosis of tuberculosis. Bull Int Un Tuberc 34:9-35, 1964 MedlineGoogle Scholar9. WALLACEDIENA RB: Unpublished observations Google Scholar10. PARLETTCHU RY: Observations on circulating antibody responses to mycobacterial stimuli. Amer J Clin Path 45: 552-561, 1966 CrossrefMedlineGoogle Scholar11. WALLACEDIENASTODDART RBT: A bentonite flocculating factor in cancer sera. Rev Canad Biol 29:203-205, 1970 MedlineGoogle Scholar12. WALLACEDIENAJESSAMINE RBA: Circulating antibody response in BCG vaccination, tuberculous infection and sarcoidosis. Canad Med Ass J 96:585-588, 1967 MedlineGoogle Scholar13. DIENAYUGIWALLACE BHR: The bentonite flocculation test in the serology of tuberculosis. I. Purification of BCG antigens. Canad J Microbiol 14:881-886, 1968 CrossrefMedlineGoogle Scholar14. WALLACECARRIEREDIENA RJB: The bentonite flocculation test in the serology of tuberculosis. II. Detection of tuberculosis in cattle. Ibid., pp. 887-890 Google Scholar15. CARRIEREWALLACEBARRETT JRB: Mycobacterial antibody response in experimentally infected animals. Ibid., pp. 923-925 Google Scholar16. CARRIEREWALLACEDIENA JRB: An appraisal of the bentonite flocculation test in the detection of bovine tuberculosis. Canad J Comp Med. In press Google Scholar17. DIENA B: Serology in tuberculosis and the bentonite flocculation test. Canad Med Ass J 99:763-764, 1968 MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Canadian Communicable Disease Centre Department of National Health and Welfare Ottawa Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA longitudinal study of antibody titres to antigen 6 in patients with bone and joint tuberculosisA Pilot Study Concerning the Early Immunosuppressive Effects of Rifampin in Man 1 July 1971Volume 75, Issue 1Page: 132-134KeywordsBacille calmette guerinBacillusChemotherapyDiagnostic radiologyMorbidityMortalitySerodiagnosisTuberculinTuberculosis Issue Published: 1 July 1971 PDF downloadLoading ..." @default.
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• W1968571725 title "Problems in the Serodiagnosis of Tuberculosis" @default.
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