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- W1968589047 abstract "Small, dense LDL particles have been associated with increased triglyceride ([TG]), apolipoprotein-B and reduced high-density lipoprotein-cholesterol ([HDLC]) concentrations, as well as increased CVD risk. An increase in LDL diameter was observed following prolonged strenuous exercise in trained men and women; however, the caloric expenditure of the exercise performed was not representative of typical exercise practices. An exercise volume of 500 kcal has elicited an increase in [HDL-C] and reduction in [TG] in sedentary men. It was hypothesized that a similar exercise energy expenditure would promote an increase in LDL and HDL particle diameter. PURPOSE To determine the response of LDL and HDL particle diameter following a single bout of aerobic exercise in women. METHODS Moderately active, non-smoking, premenopausal, normally menstruating, women (n=12; Mean±SD, age=24.1 ± 7.8 yrs, ht=161.8 ± 5.7 cm, wt=65.6 ± 10.8 kg, BMI=25.1 ± 4.5 kg·m-2, %BF=28.0 ± 6.1%, VO2peak=32.1 ± 6.1 mL·kg-1·min-1) volunteered to participate. Each participant performed a single bout of treadmill exercise at ∼65% VO2peak until 500 kcal were expended. Fasting (12h) blood samples were collected immediately prior to exercise and at 24h and 48h post-exercise. Using a non-denaturing PAGE, LDL and HDL peak diameters were measured. Peak diameters were calculated from the migration distance of each lipoprotein peak relative to albumin. A one-way ANOVA with repeated measures was employed. The criterion reference for statistical significance was set at a p<0.05. RESULTS No significant changes in LDL and HDL particle diameters were observed post-exercise. Pearson-product correlations revealed that pre-exercise LDL diameter was significantly associated with body mass (r= −0.67, p<0.05) and fat mass (r= −0.58, p<0.05). Additionally, [HDL-C] and [HDL2-C] were associated with HDL3a diameter (r= −0.71 and −0.70, p<0.05, respectively). CONCLUSIONS A single bout of treadmill exercise at ∼65% VO2peak expending 500 kcal was insuf.cient to modify LDL and HDL particle diameters.Table" @default.
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- W1968589047 date "2005-05-01" @default.
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- W1968589047 title "Acute Response Of Lipoprotein Particle Diameters Following Aerobic Exercise In Women" @default.
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