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• W1968602010 abstract "A number of delivery agents, such as proteins, liposomes, micelles, and nanoparticles, are utilized for transporting pharmaceutical agents in a physiological environment. This Letter focuses on the use of the copper(II) ion and its potential role as a delivery agent for the taxanes and taxol couple to a malaria drug. Nuclear magnetic resonance (NMR, 1H, 13C, 15N), Mass Spectrometry (LC-MS, MALDI-TOF, FT-ICR) and computational methods are used to examine the structure of the complex. The National Cancer Institute’s benchmark 60 cell line panel is used to compare the efficacy of the copper–taxol and copper–taxol–hydroxychloroquin complexes to that of iron–taxol and pure taxol." @default.
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• W1968602010 date "2014-01-01" @default.
• W1968602010 modified "2023-09-27" @default.
• W1968602010 title "Copper ion as a delivery platform for taxanes and taxane complexes" @default.
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• W1968602010 doi "https://doi.org/10.1016/j.bmcl.2013.10.073" @default.
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