FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968617875> ?p ?o ?g. }

• W1968617875 endingPage "107" @default.
• W1968617875 startingPage "107" @default.
• W1968617875 abstract "The epidermal growth factor receptor (EGFR) is a surrogate marker for basal-like breast cancer. A recent study suggested that EGFR may be used as a target for breast cancer treatment.A total of 706 invasive ductal carcinomas (IDC) of the breast were immunophenotyped, and 82 cases with EGFR protein expression were studied for EGFR gene amplification.EGFR protein was expressed in 121 of 706 IDCs (17.1%); 5.9% were of luminal type, 25.3% of epidermal growth factor receptor 2 (HER-2) type, and 79.3% of basal-like tumors. EGFR gene amplification and high polysomy (fluorescent in situ hybridization [FISH]-positive) were found in 18 of 82 cases (22.0%); 41.2% of the HER-2(+), EGFR(+), cytokeratin 5/6(-) (CK5/6(-)) group, 11.2% of the HER-2(-), EGFR(+), CK5/6(-) group, and 19.1% of the HER-2(-), EGFR(+), CK5/6(+) group. FISH-positive cases were detected in 8.3% of the EGFR protein 1(+) expression cases, 15.9% of 2(+) expression cases, and 38.5% of 3(+) expression cases. In group 2, the tumors had a high Ki-67 labeling (>60%), but the patients showed better disease-free survival than those with tumors that co-expressed HER-2 or CK5/6.EGFR-directed therapy can be considered in breast cancer patients with EGFR protein overexpression and gene amplification, and its therapeutic implication should be determined in HER-2 type breast cancer patients." @default.
• W1968617875 created "2016-06-24" @default.
• W1968617875 creator A5009008971 @default.
• W1968617875 creator A5009126066 @default.
• W1968617875 creator A5018905527 @default.
• W1968617875 creator A5021046796 @default.
• W1968617875 creator A5043315250 @default.
• W1968617875 creator A5059664573 @default.
• W1968617875 creator A5077546080 @default.
• W1968617875 date "2013-01-01" @default.
• W1968617875 modified "2023-09-30" @default.
• W1968617875 title "<i>EGFR</i>Gene Amplification and Protein Expression in Invasive Ductal Carcinoma of the Breast" @default.
• W1968617875 cites W1606526901 @default.
• W1968617875 cites W1956266177 @default.
• W1968617875 cites W1973807269 @default.
• W1968617875 cites W1974423469 @default.
• W1968617875 cites W1988055795 @default.
• W1968617875 cites W1989487223 @default.
• W1968617875 cites W1993969876 @default.
• W1968617875 cites W2033616612 @default.
• W1968617875 cites W2043409879 @default.
• W1968617875 cites W2045793286 @default.
• W1968617875 cites W2075883741 @default.
• W1968617875 cites W2095950656 @default.
• W1968617875 cites W2107571953 @default.
• W1968617875 cites W2113843552 @default.
• W1968617875 cites W2116161594 @default.
• W1968617875 cites W2121930714 @default.
• W1968617875 cites W2122885616 @default.
• W1968617875 cites W2130900820 @default.
• W1968617875 cites W2148783573 @default.
• W1968617875 cites W2149908785 @default.
• W1968617875 cites W2153933760 @default.
• W1968617875 cites W2154946742 @default.
• W1968617875 cites W2157285286 @default.
• W1968617875 cites W2158997529 @default.
• W1968617875 doi "https://doi.org/10.4132/koreanjpathol.2013.47.2.107" @default.
• W1968617875 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3647122" @default.
• W1968617875 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23667369" @default.
• W1968617875 hasPublicationYear "2013" @default.
• W1968617875 type Work @default.
• W1968617875 sameAs 1968617875 @default.
• W1968617875 citedByCount "20" @default.
• W1968617875 countsByYear W19686178752013 @default.
• W1968617875 countsByYear W19686178752014 @default.
• W1968617875 countsByYear W19686178752015 @default.
• W1968617875 countsByYear W19686178752016 @default.
• W1968617875 countsByYear W19686178752017 @default.
• W1968617875 countsByYear W19686178752018 @default.
• W1968617875 countsByYear W19686178752019 @default.
• W1968617875 countsByYear W19686178752020 @default.
• W1968617875 countsByYear W19686178752021 @default.
• W1968617875 countsByYear W19686178752022 @default.
• W1968617875 crossrefType "journal-article" @default.
• W1968617875 hasAuthorship W1968617875A5009008971 @default.
• W1968617875 hasAuthorship W1968617875A5009126066 @default.
• W1968617875 hasAuthorship W1968617875A5018905527 @default.
• W1968617875 hasAuthorship W1968617875A5021046796 @default.
• W1968617875 hasAuthorship W1968617875A5043315250 @default.
• W1968617875 hasAuthorship W1968617875A5059664573 @default.
• W1968617875 hasAuthorship W1968617875A5077546080 @default.
• W1968617875 hasBestOaLocation W19686178751 @default.
• W1968617875 hasConcept C104317684 @default.
• W1968617875 hasConcept C121608353 @default.
• W1968617875 hasConcept C126322002 @default.
• W1968617875 hasConcept C142724271 @default.
• W1968617875 hasConcept C143998085 @default.
• W1968617875 hasConcept C150194340 @default.
• W1968617875 hasConcept C204232928 @default.
• W1968617875 hasConcept C2777542201 @default.
• W1968617875 hasConcept C2778024521 @default.
• W1968617875 hasConcept C2779012181 @default.
• W1968617875 hasConcept C2779306644 @default.
• W1968617875 hasConcept C2779438470 @default.
• W1968617875 hasConcept C2781303241 @default.
• W1968617875 hasConcept C30481170 @default.
• W1968617875 hasConcept C502942594 @default.
• W1968617875 hasConcept C530470458 @default.
• W1968617875 hasConcept C55493867 @default.
• W1968617875 hasConcept C71924100 @default.
• W1968617875 hasConcept C7602840 @default.
• W1968617875 hasConcept C81439078 @default.
• W1968617875 hasConcept C86803240 @default.
• W1968617875 hasConceptScore W1968617875C104317684 @default.
• W1968617875 hasConceptScore W1968617875C121608353 @default.
• W1968617875 hasConceptScore W1968617875C126322002 @default.
• W1968617875 hasConceptScore W1968617875C142724271 @default.
• W1968617875 hasConceptScore W1968617875C143998085 @default.
• W1968617875 hasConceptScore W1968617875C150194340 @default.
• W1968617875 hasConceptScore W1968617875C204232928 @default.
• W1968617875 hasConceptScore W1968617875C2777542201 @default.
• W1968617875 hasConceptScore W1968617875C2778024521 @default.
• W1968617875 hasConceptScore W1968617875C2779012181 @default.
• W1968617875 hasConceptScore W1968617875C2779306644 @default.
• W1968617875 hasConceptScore W1968617875C2779438470 @default.
• W1968617875 hasConceptScore W1968617875C2781303241 @default.
• W1968617875 hasConceptScore W1968617875C30481170 @default.
• W1968617875 hasConceptScore W1968617875C502942594 @default.

• next