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• W1968620439 abstract "Abstract Favorable cell‐material interaction and the absence of undesirable reaction from the host body defence system play a critical role in determining the success and long‐term survival of the implants. Substitution of various elements into hydroxyapatite (HA) has been done to alter its chemical composition, thereby mimicking that of the bone mineral. In this study, a cosubstituted nanosized apatite (Ag/Si‐HA) containing Ag (0.3 wt %) and Si (0.8 wt %) was synthesized by an aqueous precipitation technique. The synthesized Ag/Si‐HA displayed a rod‐like morphology of dimensions ∼50 nm in length and ∼15 nm in width, as observed from the transmission electron microscope image. With an increase in temperature, the aspect ratio of nanosized Ag/Si‐HA decreased, whilst the size increased. Autoclaving was used to achieve sufficient crystallinity while maintaining the rod‐like morphology and size that were comparable to that of the bone apatite. A pure Ag/Si‐HA was produced without any undesirable secondary phases, as evidenced from the X‐ray diffraction and thermal gravimetric results. The Ag/Si cosubstitution affected the lattice cell parameters, in particularly the a‐ and c‐ axes which further led to an expansion of the unit cell volume. In addition, the relative intensity of the hydroxyl vibrational bands was reduced. These results demonstrated that a stable phase‐pure Ag/Si‐HA was produced using an aqueous precipitation reaction. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012." @default.
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• W1968620439 date "2011-11-21" @default.
• W1968620439 modified "2023-10-12" @default.
• W1968620439 title "Synthesis and characterization of silver/silicon-cosubstituted nanohydroxyapatite" @default.
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• W1968620439 doi "https://doi.org/10.1002/jbm.b.31951" @default.
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