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- W1968628393 abstract "Hypoxia-responsive amino acids are indispensable in the preparation of hypoxic tumor-specific peptidyl prodrugs. In this paper, the design and synthesis of a reduction-responsive amino acid that induces peptide bond cleavage after reduction of the nitro group are described. Application to hypoxia-responsive peptide bond cleavage system is also reported." @default.
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- W1968628393 date "2012-04-13" @default.
- W1968628393 modified "2023-10-17" @default.
- W1968628393 title "Development of a Reduction-Responsive Amino Acid that Induces Peptide Bond Cleavage in Hypoxic Cells" @default.
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- W1968628393 doi "https://doi.org/10.1002/cbic.201200141" @default.
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