FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968636995> ?p ?o ?g. }

• W1968636995 endingPage "20" @default.
• W1968636995 startingPage "14" @default.
• W1968636995 abstract "Background and Purpose— The local renin-angiotensin system (RAS) and cyclooxygenase-2 contribute to the activation of nuclear factor κB (NFκB) and C-reactive protein (CRP). We hypothesized that the combination of RAS blockers (RASb) and ASA reduces NFκB and CRP within atherosclerotic plaques. Methods— Patients undergoing carotid endarterectomy were divided into groups according to treatment (RASb–acetylsalicylic acid [ASA], ASA, RASb, and control). The expression of NFκB, CRP, and CD40L was analyzed through Western blots in the obtained plaques. Results— Plaques from patients treated with the combination of RASb and ASA showed lower expression of NFκB (25.4±9.8 densitometric units [DU]) than those of the control group (57.6±13.2 DU, P =0.03) as well as lower expression of CRP (20.9±9.6 DU) than those of the other treatment groups (ASA 86.1±13 DU, RASb 88.4±31 DU, controls 67.8±18.6, P =0.004). A negative expression of NFκB was associated with a reduced incidence of symptoms compared with a positive expression (5/33 [15.1%] versus 14/35 [40%], P =0.031). Conclusions— The combined treatment with RASb and ASA decreases the expression of inflammatory markers in atherosclerosis in humans. This study supports the role of the local RAS and cyclooxygenase-2 in the progression of atherosclerosis." @default.
• W1968636995 created "2016-06-24" @default.
• W1968636995 creator A5001528741 @default.
• W1968636995 creator A5006238168 @default.
• W1968636995 creator A5011653011 @default.
• W1968636995 creator A5018039379 @default.
• W1968636995 creator A5024324933 @default.
• W1968636995 creator A5027367849 @default.
• W1968636995 creator A5029129626 @default.
• W1968636995 creator A5051958177 @default.
• W1968636995 creator A5078652101 @default.
• W1968636995 date "2005-01-01" @default.
• W1968636995 modified "2023-10-02" @default.
• W1968636995 title "Concurrent Treatment With Renin-Angiotensin System Blockers and Acetylsalicylic Acid Reduces Nuclear Factor κB Activation and C-Reactive Protein Expression in Human Carotid Artery Plaques" @default.
• W1968636995 cites W1558367558 @default.
• W1968636995 cites W1598476508 @default.
• W1968636995 cites W1965883902 @default.
• W1968636995 cites W1973293258 @default.
• W1968636995 cites W1973303480 @default.
• W1968636995 cites W1974172203 @default.
• W1968636995 cites W1986858103 @default.
• W1968636995 cites W1998624053 @default.
• W1968636995 cites W2004680931 @default.
• W1968636995 cites W2006353464 @default.
• W1968636995 cites W2016126193 @default.
• W1968636995 cites W2029723377 @default.
• W1968636995 cites W2032766057 @default.
• W1968636995 cites W2039567774 @default.
• W1968636995 cites W2040028126 @default.
• W1968636995 cites W2042192097 @default.
• W1968636995 cites W2046117118 @default.
• W1968636995 cites W2056034929 @default.
• W1968636995 cites W2057764408 @default.
• W1968636995 cites W2057809694 @default.
• W1968636995 cites W2059279349 @default.
• W1968636995 cites W2063396563 @default.
• W1968636995 cites W2063572291 @default.
• W1968636995 cites W2077741802 @default.
• W1968636995 cites W2084661093 @default.
• W1968636995 cites W2094848681 @default.
• W1968636995 cites W2095948308 @default.
• W1968636995 cites W2097717405 @default.
• W1968636995 cites W2097796010 @default.
• W1968636995 cites W2098758394 @default.
• W1968636995 cites W2099939995 @default.
• W1968636995 cites W2109958590 @default.
• W1968636995 cites W2131557193 @default.
• W1968636995 cites W2137948074 @default.
• W1968636995 cites W2141715766 @default.
• W1968636995 cites W2142554660 @default.
• W1968636995 cites W2144073331 @default.
• W1968636995 cites W2153157231 @default.
• W1968636995 cites W2153551773 @default.
• W1968636995 cites W2156541448 @default.
• W1968636995 cites W2170555676 @default.
• W1968636995 cites W2321636951 @default.
• W1968636995 cites W4230842714 @default.
• W1968636995 cites W98703494 @default.
• W1968636995 doi "https://doi.org/10.1161/01.str.0000150643.08420.78" @default.
• W1968636995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15576654" @default.
• W1968636995 hasPublicationYear "2005" @default.
• W1968636995 type Work @default.
• W1968636995 sameAs 1968636995 @default.
• W1968636995 citedByCount "47" @default.
• W1968636995 countsByYear W19686369952012 @default.
• W1968636995 countsByYear W19686369952013 @default.
• W1968636995 countsByYear W19686369952014 @default.
• W1968636995 countsByYear W19686369952015 @default.
• W1968636995 countsByYear W19686369952016 @default.
• W1968636995 countsByYear W19686369952017 @default.
• W1968636995 countsByYear W19686369952018 @default.
• W1968636995 countsByYear W19686369952019 @default.
• W1968636995 countsByYear W19686369952020 @default.
• W1968636995 countsByYear W19686369952021 @default.
• W1968636995 countsByYear W19686369952022 @default.
• W1968636995 countsByYear W19686369952023 @default.
• W1968636995 crossrefType "journal-article" @default.
• W1968636995 hasAuthorship W1968636995A5001528741 @default.
• W1968636995 hasAuthorship W1968636995A5006238168 @default.
• W1968636995 hasAuthorship W1968636995A5011653011 @default.
• W1968636995 hasAuthorship W1968636995A5018039379 @default.
• W1968636995 hasAuthorship W1968636995A5024324933 @default.
• W1968636995 hasAuthorship W1968636995A5027367849 @default.
• W1968636995 hasAuthorship W1968636995A5029129626 @default.
• W1968636995 hasAuthorship W1968636995A5051958177 @default.
• W1968636995 hasAuthorship W1968636995A5078652101 @default.
• W1968636995 hasBestOaLocation W19686369951 @default.
• W1968636995 hasConcept C126322002 @default.
• W1968636995 hasConcept C134018914 @default.
• W1968636995 hasConcept C198710026 @default.
• W1968636995 hasConcept C2781068581 @default.
• W1968636995 hasConcept C2987047532 @default.
• W1968636995 hasConcept C71924100 @default.
• W1968636995 hasConcept C84393581 @default.
• W1968636995 hasConcept C98274493 @default.
• W1968636995 hasConceptScore W1968636995C126322002 @default.
• W1968636995 hasConceptScore W1968636995C134018914 @default.
• W1968636995 hasConceptScore W1968636995C198710026 @default.

• next