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- W1968642771 abstract "The noradrenergic neurons of the locus coeruleus in the albino rat have been mapped and characterized morphologically with the unlabeled peroxidase anti-peroxidase method employing an antiserum to rat dopamine β-hydroxylase. A comprehensive series of low-power photomicrographs of immunocytochemically stained sections is presented depicting the full extent of this nucleus in relationship to other structural landmarks. The paper provides the first detailed atlas of dopamine β-hydroxylase-immunoreactive cells in the pontine and mesencephalic tegmentum of the rat. In addition, this study provides for the first time a description of dopamine β-hydroxylase-positive cells in the periaqueductal gray of the caudal midbrain, that have not previously been visualized, illustrations of dopamine β-hydroxylase-positive cells in the roof of the IVth ventricle that extend their dendrites between ependymal cells to the ventricular surface, a depiction of the extensively ramified dendrites that characterize noradrenergic cells in the ventral division of the locus coeruleus, and morphological evidence that cells of the locus coeruleus group can be divided into four contiguous but cytologically distinct sets. The data presented in this paper provide a guide for planning and interpreting studies of the locus coeruleus, in particular, for the elucidation of its afferents and efferents, the electrophysiologic characteristics of its cells, and the behavioral effects of lesions." @default.
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- W1968642771 date "1980-01-01" @default.
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- W1968642771 title "The locus coeruleus in the rat: An immunohistochemical delineation" @default.
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- W1968642771 doi "https://doi.org/10.1016/0306-4522(80)90068-8" @default.
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