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- W1968645058 abstract "A water-soluble and stable camptothecin derivative, CPT-11, was found to possess a strong antitumor activity against various murine tumors. In the present study, CPT-11 was tested against ten human gastrointestinal cancer xenograft lines carried by nude mice. CPT-11 was very effective against nine xenograft lines, with the exception of one xenograft. On the other hand, VP-16 was ineffective against all these xenograft lines. Therefore, CPT-11 is expected to be clinically more effective against gastrointestinal cancer than the topo II targeting agent." @default.
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- W1968645058 date "1993-12-01" @default.
- W1968645058 modified "2023-09-24" @default.
- W1968645058 title "Growth inhibition of human gastrointestinal cancer xenograft lines by treatment with CPT-11 and VP-16" @default.
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- W1968645058 doi "https://doi.org/10.1002/jso.2930540404" @default.
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