Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968652783> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W1968652783 endingPage "294" @default.
- W1968652783 startingPage "288" @default.
- W1968652783 abstract "The aim of this study was to assess bone mineral density (BMD) and biochemical bone metabolism markers in patients with bone tumors after anti-cancer treatment. The study included 27 patients (median age 15 years) with malignant bone tumors and 27 healthy children. In all subjects, BMD and body composition were measured by dual-energy x-ray absorptiometry. Serum bone markers were determined by immunoenzymatic assays. After completion of treatment, patients with bone tumors had significantly decreased total and lumbar spine BMD. We observed lower calcium and vitamin D levels in patients and comparable values of bone turnover markers (carboxyterminal telopeptide of collagen type I - CTX, bone alkaline phosphatase - BALP and osteocalcin - OC) in both groups of children. However, the level of carboxylated osteocalcin (cOC) was significantly lower (p<0.01) and undercarboxylated OC (ucOC) was higher (p<0.05) in patients than in controls. Additionally, we observed similar values of anthropometric parameters in the subgroups of patients treated with methotrexate (MTX) or without MTX. In patients treated without MTX we found lower (p<0.05) ratio of cOC/ucOC, lower vitamin D level and higher CTX concentrations. Patients with bone tumors after anticancer treatment had decreased bone mineral density and alterations in bone metabolism markers with potential decrease in bone formation.bone cancer survivors, bone mineral density, bone formation markers, bone resorption markers, methotrexate." @default.
- W1968652783 created "2016-06-24" @default.
- W1968652783 creator A5014043166 @default.
- W1968652783 creator A5022457834 @default.
- W1968652783 creator A5047881207 @default.
- W1968652783 creator A5054331781 @default.
- W1968652783 creator A5068316086 @default.
- W1968652783 creator A5080236085 @default.
- W1968652783 creator A5089044393 @default.
- W1968652783 date "2015-01-01" @default.
- W1968652783 modified "2023-10-17" @default.
- W1968652783 title "Decreased bone mineral density and alteration in biochemical bone metabolism markers in children affected by bone tumors after completion of therapy" @default.
- W1968652783 doi "https://doi.org/10.4149/neo_2015_034" @default.
- W1968652783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25591594" @default.
- W1968652783 hasPublicationYear "2015" @default.
- W1968652783 type Work @default.
- W1968652783 sameAs 1968652783 @default.
- W1968652783 citedByCount "3" @default.
- W1968652783 countsByYear W19686527832021 @default.
- W1968652783 countsByYear W19686527832022 @default.
- W1968652783 countsByYear W19686527832023 @default.
- W1968652783 crossrefType "journal-article" @default.
- W1968652783 hasAuthorship W1968652783A5014043166 @default.
- W1968652783 hasAuthorship W1968652783A5022457834 @default.
- W1968652783 hasAuthorship W1968652783A5047881207 @default.
- W1968652783 hasAuthorship W1968652783A5054331781 @default.
- W1968652783 hasAuthorship W1968652783A5068316086 @default.
- W1968652783 hasAuthorship W1968652783A5080236085 @default.
- W1968652783 hasAuthorship W1968652783A5089044393 @default.
- W1968652783 hasBestOaLocation W19686527831 @default.
- W1968652783 hasConcept C125870589 @default.
- W1968652783 hasConcept C126322002 @default.
- W1968652783 hasConcept C131075544 @default.
- W1968652783 hasConcept C134018914 @default.
- W1968652783 hasConcept C160160445 @default.
- W1968652783 hasConcept C170033053 @default.
- W1968652783 hasConcept C181199279 @default.
- W1968652783 hasConcept C185592680 @default.
- W1968652783 hasConcept C2776541429 @default.
- W1968652783 hasConcept C2776886416 @default.
- W1968652783 hasConcept C2779329777 @default.
- W1968652783 hasConcept C55493867 @default.
- W1968652783 hasConcept C673006 @default.
- W1968652783 hasConcept C71924100 @default.
- W1968652783 hasConceptScore W1968652783C125870589 @default.
- W1968652783 hasConceptScore W1968652783C126322002 @default.
- W1968652783 hasConceptScore W1968652783C131075544 @default.
- W1968652783 hasConceptScore W1968652783C134018914 @default.
- W1968652783 hasConceptScore W1968652783C160160445 @default.
- W1968652783 hasConceptScore W1968652783C170033053 @default.
- W1968652783 hasConceptScore W1968652783C181199279 @default.
- W1968652783 hasConceptScore W1968652783C185592680 @default.
- W1968652783 hasConceptScore W1968652783C2776541429 @default.
- W1968652783 hasConceptScore W1968652783C2776886416 @default.
- W1968652783 hasConceptScore W1968652783C2779329777 @default.
- W1968652783 hasConceptScore W1968652783C55493867 @default.
- W1968652783 hasConceptScore W1968652783C673006 @default.
- W1968652783 hasConceptScore W1968652783C71924100 @default.
- W1968652783 hasIssue "02" @default.
- W1968652783 hasLocation W19686527831 @default.
- W1968652783 hasLocation W19686527832 @default.
- W1968652783 hasOpenAccess W1968652783 @default.
- W1968652783 hasPrimaryLocation W19686527831 @default.
- W1968652783 hasRelatedWork W1967422973 @default.
- W1968652783 hasRelatedWork W1985535358 @default.
- W1968652783 hasRelatedWork W2012733509 @default.
- W1968652783 hasRelatedWork W2024155257 @default.
- W1968652783 hasRelatedWork W2050502884 @default.
- W1968652783 hasRelatedWork W2053638911 @default.
- W1968652783 hasRelatedWork W2067199708 @default.
- W1968652783 hasRelatedWork W2077499275 @default.
- W1968652783 hasRelatedWork W2091140190 @default.
- W1968652783 hasRelatedWork W2128714854 @default.
- W1968652783 hasVolume "62" @default.
- W1968652783 isParatext "false" @default.
- W1968652783 isRetracted "false" @default.
- W1968652783 magId "1968652783" @default.
- W1968652783 workType "article" @default.