FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968677039> ?p ?o ?g. }

• W1968677039 endingPage "532" @default.
• W1968677039 startingPage "518" @default.
• W1968677039 abstract "Keratin intermediate filament networks are part of the cytoskeleton in epithelial cells. They were found to regulate viscoelastic properties and motility of cancer cells. Due to unique biochemical properties of keratin polymers, the knowledge of the mechanisms controlling keratin network formation is incomplete. A combination of deterministic and stochastic modeling techniques can be a valuable source of information since they can describe known mechanisms of network evolution while reflecting the uncertainty with respect to a variety of molecular events. We applied the concept of piecewise-deterministic Markov processes to the modeling of keratin network formation with high spatiotemporal resolution. The deterministic component describes the diffusion-driven evolution of a pool of soluble keratin filament precursors fueling various network formation processes. Instants of network formation events are determined by a stochastic point process on the time axis. A probability distribution controlled by model parameters exercises control over the frequency of different mechanisms of network formation to be triggered. Locations of the network formation events are assigned dependent on the spatial distribution of the soluble pool of filament precursors. Based on this modeling approach, simulation studies revealed that the architecture of keratin networks mostly depends on the balance between filament elongation and branching processes. The spatial distribution of network mesh size, which strongly influences the mechanical characteristics of filament networks, is modulated by lateral annealing processes. This mechanism which is a specific feature of intermediate filament networks appears to be a major and fast regulator of cell mechanics." @default.
• W1968677039 created "2016-06-24" @default.
• W1968677039 creator A5018448730 @default.
• W1968677039 creator A5026524546 @default.
• W1968677039 creator A5026786303 @default.
• W1968677039 creator A5036144786 @default.
• W1968677039 creator A5042036645 @default.
• W1968677039 creator A5079062349 @default.
• W1968677039 date "2009-02-01" @default.
• W1968677039 modified "2023-10-18" @default.
• W1968677039 title "Simulating the formation of keratin filament networks by a piecewise-deterministic Markov process" @default.
• W1968677039 cites W1968261842 @default.
• W1968677039 cites W1969023545 @default.
• W1968677039 cites W1984606625 @default.
• W1968677039 cites W1985936786 @default.
• W1968677039 cites W1986931808 @default.
• W1968677039 cites W1993194546 @default.
• W1968677039 cites W1999301713 @default.
• W1968677039 cites W2008792915 @default.
• W1968677039 cites W2014227262 @default.
• W1968677039 cites W2016070600 @default.
• W1968677039 cites W2017430060 @default.
• W1968677039 cites W2018670096 @default.
• W1968677039 cites W2022382803 @default.
• W1968677039 cites W2028094847 @default.
• W1968677039 cites W2042025816 @default.
• W1968677039 cites W2048694948 @default.
• W1968677039 cites W2065632389 @default.
• W1968677039 cites W2067129601 @default.
• W1968677039 cites W2070852036 @default.
• W1968677039 cites W2073704662 @default.
• W1968677039 cites W2074401358 @default.
• W1968677039 cites W2075119539 @default.
• W1968677039 cites W2075866529 @default.
• W1968677039 cites W2079277100 @default.
• W1968677039 cites W2081504673 @default.
• W1968677039 cites W2085061065 @default.
• W1968677039 cites W2087944824 @default.
• W1968677039 cites W2089911149 @default.
• W1968677039 cites W2098800695 @default.
• W1968677039 cites W2102921200 @default.
• W1968677039 cites W2107059134 @default.
• W1968677039 cites W2112426918 @default.
• W1968677039 cites W2126516692 @default.
• W1968677039 cites W2126531317 @default.
• W1968677039 cites W2128443448 @default.
• W1968677039 cites W2132190405 @default.
• W1968677039 cites W2136326104 @default.
• W1968677039 cites W2141807385 @default.
• W1968677039 cites W2155418451 @default.
• W1968677039 cites W2157924726 @default.
• W1968677039 cites W2169274898 @default.
• W1968677039 doi "https://doi.org/10.1016/j.jtbi.2008.09.044" @default.
• W1968677039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19014958" @default.
• W1968677039 hasPublicationYear "2009" @default.
• W1968677039 type Work @default.
• W1968677039 sameAs 1968677039 @default.
• W1968677039 citedByCount "19" @default.
• W1968677039 countsByYear W19686770392012 @default.
• W1968677039 countsByYear W19686770392013 @default.
• W1968677039 countsByYear W19686770392015 @default.
• W1968677039 countsByYear W19686770392016 @default.
• W1968677039 countsByYear W19686770392017 @default.
• W1968677039 countsByYear W19686770392019 @default.
• W1968677039 countsByYear W19686770392021 @default.
• W1968677039 countsByYear W19686770392022 @default.
• W1968677039 countsByYear W19686770392023 @default.
• W1968677039 crossrefType "journal-article" @default.
• W1968677039 hasAuthorship W1968677039A5018448730 @default.
• W1968677039 hasAuthorship W1968677039A5026524546 @default.
• W1968677039 hasAuthorship W1968677039A5026786303 @default.
• W1968677039 hasAuthorship W1968677039A5036144786 @default.
• W1968677039 hasAuthorship W1968677039A5042036645 @default.
• W1968677039 hasAuthorship W1968677039A5079062349 @default.
• W1968677039 hasBestOaLocation W19686770392 @default.
• W1968677039 hasConcept C111919701 @default.
• W1968677039 hasConcept C119857082 @default.
• W1968677039 hasConcept C136764020 @default.
• W1968677039 hasConcept C14228908 @default.
• W1968677039 hasConcept C142669718 @default.
• W1968677039 hasConcept C1491633281 @default.
• W1968677039 hasConcept C151730666 @default.
• W1968677039 hasConcept C159985019 @default.
• W1968677039 hasConcept C185592680 @default.
• W1968677039 hasConcept C186060115 @default.
• W1968677039 hasConcept C192562407 @default.
• W1968677039 hasConcept C28225019 @default.
• W1968677039 hasConcept C41008148 @default.
• W1968677039 hasConcept C55493867 @default.
• W1968677039 hasConcept C60644358 @default.
• W1968677039 hasConcept C68416499 @default.
• W1968677039 hasConcept C78383274 @default.
• W1968677039 hasConcept C81241287 @default.
• W1968677039 hasConcept C86803240 @default.
• W1968677039 hasConcept C98045186 @default.
• W1968677039 hasConcept C98763669 @default.
• W1968677039 hasConceptScore W1968677039C111919701 @default.
• W1968677039 hasConceptScore W1968677039C119857082 @default.

• next