Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968700754> ?p ?o ?g. }
- W1968700754 abstract "Clinical studies are limited regarding the role of human nociceptin/orphanin FQ (N/OFQ) in ischemic cardiovascular diseases, which are still the number one cause of death in the developed world. The aim of our study was to measure the plasma levels of N/OFQ in patients with chronic ischemic cardiovascular diseases in a pilot study.Our study population consisted of 22 patients presenting symptoms of stable angina pectoris (SAP): 12 severe Canadian Cardiovascular Society (CCS) III-IV functional class, and 10 with milder SAP (CCS II-III). 12 patients were also enrolled with chronic peripheral artery disease (9 with intermittent claudication; 3 with rest pain and gangrene). Patients were asked to avoid any exertion or given analgetics for their rest pain. Patients had no episodes of chest or limb pain in 1week before their fasting blood samples were taken and N/OFQ plasma levels were measured by radioimmunoassay. 14 healthy subjects without any cardiac risk factors served as a control group.N/OFQ levels were significantly lower in patient groups with severe vs. milder chronic angina (p<0.05) and vs. control subjects (p<0.01). Patients suffering from peripheral artery disease had also a lower plasma N/OFQ levels than in healthy controls (p<0.01). Our findings show that chronic ischemic conditions of atherosclerotic origin are associated with significantly lower plasma N/OFQ levels." @default.
- W1968700754 created "2016-06-24" @default.
- W1968700754 creator A5009774859 @default.
- W1968700754 creator A5021208170 @default.
- W1968700754 creator A5028935567 @default.
- W1968700754 creator A5029019754 @default.
- W1968700754 creator A5033909477 @default.
- W1968700754 creator A5035706880 @default.
- W1968700754 creator A5042158242 @default.
- W1968700754 creator A5058687639 @default.
- W1968700754 creator A5064181069 @default.
- W1968700754 creator A5065609260 @default.
- W1968700754 creator A5075666731 @default.
- W1968700754 date "2011-08-01" @default.
- W1968700754 modified "2023-10-09" @default.
- W1968700754 title "Plasma nociceptin/orphanin FQ levels are lower in patients with chronic ischemic cardiovascular diseases—A pilot study" @default.
- W1968700754 cites W120433712 @default.
- W1968700754 cites W136512421 @default.
- W1968700754 cites W1517300596 @default.
- W1968700754 cites W1968917233 @default.
- W1968700754 cites W1983012742 @default.
- W1968700754 cites W1983485809 @default.
- W1968700754 cites W1984353069 @default.
- W1968700754 cites W1986849025 @default.
- W1968700754 cites W1987476004 @default.
- W1968700754 cites W1989521646 @default.
- W1968700754 cites W1995872717 @default.
- W1968700754 cites W1997675350 @default.
- W1968700754 cites W2002020138 @default.
- W1968700754 cites W2003989159 @default.
- W1968700754 cites W2006445444 @default.
- W1968700754 cites W2011366397 @default.
- W1968700754 cites W2014237020 @default.
- W1968700754 cites W2016562510 @default.
- W1968700754 cites W2026631846 @default.
- W1968700754 cites W2031546653 @default.
- W1968700754 cites W2046781223 @default.
- W1968700754 cites W2049087374 @default.
- W1968700754 cites W2049869944 @default.
- W1968700754 cites W2058988366 @default.
- W1968700754 cites W2066281888 @default.
- W1968700754 cites W2066624199 @default.
- W1968700754 cites W2073133993 @default.
- W1968700754 cites W2081479384 @default.
- W1968700754 cites W2083920808 @default.
- W1968700754 cites W2093513199 @default.
- W1968700754 cites W2104761065 @default.
- W1968700754 cites W2122473579 @default.
- W1968700754 cites W2131601450 @default.
- W1968700754 cites W2136761718 @default.
- W1968700754 cites W2141289234 @default.
- W1968700754 cites W2144916874 @default.
- W1968700754 cites W2147080208 @default.
- W1968700754 cites W2154296057 @default.
- W1968700754 cites W2156650079 @default.
- W1968700754 cites W2167151839 @default.
- W1968700754 cites W2170071096 @default.
- W1968700754 cites W2410027597 @default.
- W1968700754 cites W74101889 @default.
- W1968700754 cites W2030001333 @default.
- W1968700754 doi "https://doi.org/10.1016/j.regpep.2011.01.007" @default.
- W1968700754 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21310194" @default.
- W1968700754 hasPublicationYear "2011" @default.
- W1968700754 type Work @default.
- W1968700754 sameAs 1968700754 @default.
- W1968700754 citedByCount "10" @default.
- W1968700754 countsByYear W19687007542012 @default.
- W1968700754 countsByYear W19687007542013 @default.
- W1968700754 countsByYear W19687007542014 @default.
- W1968700754 countsByYear W19687007542016 @default.
- W1968700754 countsByYear W19687007542017 @default.
- W1968700754 crossrefType "journal-article" @default.
- W1968700754 hasAuthorship W1968700754A5009774859 @default.
- W1968700754 hasAuthorship W1968700754A5021208170 @default.
- W1968700754 hasAuthorship W1968700754A5028935567 @default.
- W1968700754 hasAuthorship W1968700754A5029019754 @default.
- W1968700754 hasAuthorship W1968700754A5033909477 @default.
- W1968700754 hasAuthorship W1968700754A5035706880 @default.
- W1968700754 hasAuthorship W1968700754A5042158242 @default.
- W1968700754 hasAuthorship W1968700754A5058687639 @default.
- W1968700754 hasAuthorship W1968700754A5064181069 @default.
- W1968700754 hasAuthorship W1968700754A5065609260 @default.
- W1968700754 hasAuthorship W1968700754A5075666731 @default.
- W1968700754 hasConcept C125439840 @default.
- W1968700754 hasConcept C126322002 @default.
- W1968700754 hasConcept C141071460 @default.
- W1968700754 hasConcept C164705383 @default.
- W1968700754 hasConcept C170493617 @default.
- W1968700754 hasConcept C1862650 @default.
- W1968700754 hasConcept C2776626339 @default.
- W1968700754 hasConcept C2777466421 @default.
- W1968700754 hasConcept C2778213512 @default.
- W1968700754 hasConcept C2778310968 @default.
- W1968700754 hasConcept C2778425758 @default.
- W1968700754 hasConcept C2778704086 @default.
- W1968700754 hasConcept C2778963770 @default.
- W1968700754 hasConcept C2779881954 @default.
- W1968700754 hasConcept C2781063702 @default.
- W1968700754 hasConcept C2908647359 @default.
- W1968700754 hasConcept C3018348675 @default.