Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968720983> ?p ?o ?g. }
- W1968720983 endingPage "160" @default.
- W1968720983 startingPage "153" @default.
- W1968720983 abstract "Abstract In the past 35 years, significant findings have been made in relation to angiogenesis, and how this usually normal physiological function is converted into an abnormal state in cancer. To search for agents that can inhibit angiogenesis, and thereby prevent a tumour from proliferation and spread that is ultimately fatal to the patient, various in-vitro assays have been developed. In addition, older assays have been refined usually into high throughput screening formats, mainly by the biopharmaceutical industry in their attempts to develop novel therapeutic molecules and maintain a pipeline of lead candidates. The central aim is to extract more accurate data that would facilitate the birth of innovative mechanisms to defeat aberrant angiogenesis in-vivo. At the same time, better in-vivo models have been established, with the goal to mimic as close as possible the natural progression of various types of neoplasms in response to a good angiogenic response. More clinically relevant models are needed as anti-angiogenesis drug discovery and drug development companies fast track their lead molecules from preclinical investigations to phase I clinical trials." @default.
- W1968720983 created "2016-06-24" @default.
- W1968720983 creator A5057418546 @default.
- W1968720983 creator A5090190585 @default.
- W1968720983 date "2006-02-01" @default.
- W1968720983 modified "2023-10-10" @default.
- W1968720983 title "In-vitro and in-vivo assays for angiogenesis-modulating drug discovery and development" @default.
- W1968720983 cites W1522674317 @default.
- W1968720983 cites W1554296669 @default.
- W1968720983 cites W1967590750 @default.
- W1968720983 cites W1978139448 @default.
- W1968720983 cites W1982973867 @default.
- W1968720983 cites W1985427729 @default.
- W1968720983 cites W1993301801 @default.
- W1968720983 cites W1994097025 @default.
- W1968720983 cites W2000000541 @default.
- W1968720983 cites W2000021550 @default.
- W1968720983 cites W2014696732 @default.
- W1968720983 cites W2020299143 @default.
- W1968720983 cites W2028972436 @default.
- W1968720983 cites W2035996742 @default.
- W1968720983 cites W2036702555 @default.
- W1968720983 cites W2037761545 @default.
- W1968720983 cites W2040654021 @default.
- W1968720983 cites W2040914101 @default.
- W1968720983 cites W2049298293 @default.
- W1968720983 cites W2049704535 @default.
- W1968720983 cites W2052891209 @default.
- W1968720983 cites W2059870250 @default.
- W1968720983 cites W2068282262 @default.
- W1968720983 cites W2071981721 @default.
- W1968720983 cites W2073209811 @default.
- W1968720983 cites W2077470327 @default.
- W1968720983 cites W2080602723 @default.
- W1968720983 cites W2086151823 @default.
- W1968720983 cites W2092732789 @default.
- W1968720983 cites W2095478806 @default.
- W1968720983 cites W2096291913 @default.
- W1968720983 cites W2098671787 @default.
- W1968720983 cites W2105229473 @default.
- W1968720983 cites W2110803567 @default.
- W1968720983 cites W2120895512 @default.
- W1968720983 cites W2140723257 @default.
- W1968720983 cites W2146097802 @default.
- W1968720983 cites W2147485850 @default.
- W1968720983 cites W2154385453 @default.
- W1968720983 cites W2157057256 @default.
- W1968720983 cites W2163539442 @default.
- W1968720983 doi "https://doi.org/10.1211/jpp.58.2.0001" @default.
- W1968720983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16451742" @default.
- W1968720983 hasPublicationYear "2006" @default.
- W1968720983 type Work @default.
- W1968720983 sameAs 1968720983 @default.
- W1968720983 citedByCount "17" @default.
- W1968720983 countsByYear W19687209832013 @default.
- W1968720983 countsByYear W19687209832014 @default.
- W1968720983 countsByYear W19687209832017 @default.
- W1968720983 countsByYear W19687209832020 @default.
- W1968720983 countsByYear W19687209832022 @default.
- W1968720983 countsByYear W19687209832023 @default.
- W1968720983 crossrefType "journal-article" @default.
- W1968720983 hasAuthorship W1968720983A5057418546 @default.
- W1968720983 hasAuthorship W1968720983A5090190585 @default.
- W1968720983 hasBestOaLocation W19687209831 @default.
- W1968720983 hasConcept C14036430 @default.
- W1968720983 hasConcept C150903083 @default.
- W1968720983 hasConcept C202751555 @default.
- W1968720983 hasConcept C207001950 @default.
- W1968720983 hasConcept C2780035454 @default.
- W1968720983 hasConcept C2780394083 @default.
- W1968720983 hasConcept C2781047461 @default.
- W1968720983 hasConcept C502942594 @default.
- W1968720983 hasConcept C535046627 @default.
- W1968720983 hasConcept C55493867 @default.
- W1968720983 hasConcept C60644358 @default.
- W1968720983 hasConcept C64903051 @default.
- W1968720983 hasConcept C70721500 @default.
- W1968720983 hasConcept C71924100 @default.
- W1968720983 hasConcept C74187038 @default.
- W1968720983 hasConcept C86803240 @default.
- W1968720983 hasConcept C95444343 @default.
- W1968720983 hasConcept C98274493 @default.
- W1968720983 hasConceptScore W1968720983C14036430 @default.
- W1968720983 hasConceptScore W1968720983C150903083 @default.
- W1968720983 hasConceptScore W1968720983C202751555 @default.
- W1968720983 hasConceptScore W1968720983C207001950 @default.
- W1968720983 hasConceptScore W1968720983C2780035454 @default.
- W1968720983 hasConceptScore W1968720983C2780394083 @default.
- W1968720983 hasConceptScore W1968720983C2781047461 @default.
- W1968720983 hasConceptScore W1968720983C502942594 @default.
- W1968720983 hasConceptScore W1968720983C535046627 @default.
- W1968720983 hasConceptScore W1968720983C55493867 @default.
- W1968720983 hasConceptScore W1968720983C60644358 @default.
- W1968720983 hasConceptScore W1968720983C64903051 @default.
- W1968720983 hasConceptScore W1968720983C70721500 @default.
- W1968720983 hasConceptScore W1968720983C71924100 @default.
- W1968720983 hasConceptScore W1968720983C74187038 @default.
- W1968720983 hasConceptScore W1968720983C86803240 @default.