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- W1968726079 abstract "Gastro-oesophageal reflux (GOR) has been reported in infants presenting as ‘near-miss’ for SIDS. We have investigated the occurrence of GOR in 70 infants after the newborn period - sibs of SIDS (12), suspected tracheo-bronchial aspiration (7), troublesome possetting or choking (29), and ‘near-miss’ for SIDS (22). A subgroup with proven GOR was then studied polygraphically during sleep to assess the relationship between GOR and cardiorespiratory events. Radionuclide gastro-oesophageal scintygraphy was the initial method used to detect GOR over a 2-hour period following a feed. We observed GOR without vomiting, to the upper oesophageal/pharyngeal area in 48 infants (68%), evenly distributed among the groups studied. Fourteen infants with severe GOR were monitored polygraphically for 4 hours during sleep at night. Simultaneously, oesophageal pH was monitored to detect acid GOR. Fifty-one episodes of acid reflux were recorded. There were no episodes of prolonged central apnoea (> 15 seconds), or significant bradycardia (< 80 bpm). In 2 infants GOR coincided with obstructive apnoea > 6 seconds on 5 occasions, with coincidental fall in transcutaneous oxygen tension. This study confirmed that GOR is common in the groups selected and that acid reflux during sleep is sometimes associated with significant obstructive apnoea and hypoxaemia." @default.
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- W1968726079 date "1985-10-01" @default.
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- W1968726079 title "GASTRO-OESOPHAGEAL REFLUX AND CARDIDRESPIRATORY EVENTS IN INFANTS" @default.
- W1968726079 doi "https://doi.org/10.1203/00006450-198510000-00187" @default.
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