FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968751925> ?p ?o ?g. }

• W1968751925 endingPage "L63" @default.
• W1968751925 startingPage "L61" @default.
• W1968751925 abstract "Free energy perturbation calculations are carried out to estimate the effective pKa of an arginine (Arg) sidechain as a function of its location in the dipalmitoylphosphatidylcholine bilayer. Similar to previous all-atom simulations of the voltage sensor domain of a potassium channel in the membrane with charged Arg residues, the membrane and water structures deform to stabilize the charge of the Arg analog. As a result, the computed pKa is >7 throughout the membrane although the value is very close to 7 near the center of the bilayer. With additional stabilizations from negatively charged amino acids or lipid molecules, it is reasonable to expect that Arg in membrane proteins (once in the membrane) can adopt the protonated state despite the low dielectric nature of the bulk lipid membrane." @default.
• W1968751925 created "2016-06-24" @default.
• W1968751925 creator A5008976394 @default.
• W1968751925 creator A5036789652 @default.
• W1968751925 date "2008-04-01" @default.
• W1968751925 modified "2023-10-13" @default.
• W1968751925 title "Does Arginine Remain Protonated in the Lipid Membrane? Insights from Microscopic pKa Calculations" @default.
• W1968751925 cites W1998359737 @default.
• W1968751925 cites W2010597259 @default.
• W1968751925 cites W2025859600 @default.
• W1968751925 cites W2027408247 @default.
• W1968751925 cites W2032734987 @default.
• W1968751925 cites W2064566545 @default.
• W1968751925 cites W2066619150 @default.
• W1968751925 cites W2067174909 @default.
• W1968751925 cites W2076515696 @default.
• W1968751925 cites W2082204764 @default.
• W1968751925 cites W2084292444 @default.
• W1968751925 cites W2099008852 @default.
• W1968751925 cites W2114524505 @default.
• W1968751925 cites W2162166182 @default.
• W1968751925 cites W2171268876 @default.
• W1968751925 doi "https://doi.org/10.1529/biophysj.107.122945" @default.
• W1968751925 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2275699" @default.
• W1968751925 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18199662" @default.
• W1968751925 hasPublicationYear "2008" @default.
• W1968751925 type Work @default.
• W1968751925 sameAs 1968751925 @default.
• W1968751925 citedByCount "102" @default.
• W1968751925 countsByYear W19687519252012 @default.
• W1968751925 countsByYear W19687519252013 @default.
• W1968751925 countsByYear W19687519252014 @default.
• W1968751925 countsByYear W19687519252015 @default.
• W1968751925 countsByYear W19687519252016 @default.
• W1968751925 countsByYear W19687519252017 @default.
• W1968751925 countsByYear W19687519252018 @default.
• W1968751925 countsByYear W19687519252019 @default.
• W1968751925 countsByYear W19687519252020 @default.
• W1968751925 countsByYear W19687519252021 @default.
• W1968751925 countsByYear W19687519252022 @default.
• W1968751925 crossrefType "journal-article" @default.
• W1968751925 hasAuthorship W1968751925A5008976394 @default.
• W1968751925 hasAuthorship W1968751925A5036789652 @default.
• W1968751925 hasBestOaLocation W19687519251 @default.
• W1968751925 hasConcept C12554922 @default.
• W1968751925 hasConcept C145148216 @default.
• W1968751925 hasConcept C159467904 @default.
• W1968751925 hasConcept C178790620 @default.
• W1968751925 hasConcept C181911157 @default.
• W1968751925 hasConcept C185592680 @default.
• W1968751925 hasConcept C192157962 @default.
• W1968751925 hasConcept C2776330855 @default.
• W1968751925 hasConcept C2777468819 @default.
• W1968751925 hasConcept C2778918659 @default.
• W1968751925 hasConcept C2781172473 @default.
• W1968751925 hasConcept C30095370 @default.
• W1968751925 hasConcept C32909587 @default.
• W1968751925 hasConcept C39944091 @default.
• W1968751925 hasConcept C41625074 @default.
• W1968751925 hasConcept C515207424 @default.
• W1968751925 hasConcept C55493867 @default.
• W1968751925 hasConcept C8010536 @default.
• W1968751925 hasConcept C86803240 @default.
• W1968751925 hasConceptScore W1968751925C12554922 @default.
• W1968751925 hasConceptScore W1968751925C145148216 @default.
• W1968751925 hasConceptScore W1968751925C159467904 @default.
• W1968751925 hasConceptScore W1968751925C178790620 @default.
• W1968751925 hasConceptScore W1968751925C181911157 @default.
• W1968751925 hasConceptScore W1968751925C185592680 @default.
• W1968751925 hasConceptScore W1968751925C192157962 @default.
• W1968751925 hasConceptScore W1968751925C2776330855 @default.
• W1968751925 hasConceptScore W1968751925C2777468819 @default.
• W1968751925 hasConceptScore W1968751925C2778918659 @default.
• W1968751925 hasConceptScore W1968751925C2781172473 @default.
• W1968751925 hasConceptScore W1968751925C30095370 @default.
• W1968751925 hasConceptScore W1968751925C32909587 @default.
• W1968751925 hasConceptScore W1968751925C39944091 @default.
• W1968751925 hasConceptScore W1968751925C41625074 @default.
• W1968751925 hasConceptScore W1968751925C515207424 @default.
• W1968751925 hasConceptScore W1968751925C55493867 @default.
• W1968751925 hasConceptScore W1968751925C8010536 @default.
• W1968751925 hasConceptScore W1968751925C86803240 @default.
• W1968751925 hasIssue "8" @default.
• W1968751925 hasLocation W19687519251 @default.
• W1968751925 hasLocation W19687519252 @default.
• W1968751925 hasLocation W19687519253 @default.
• W1968751925 hasLocation W19687519254 @default.
• W1968751925 hasOpenAccess W1968751925 @default.
• W1968751925 hasPrimaryLocation W19687519251 @default.
• W1968751925 hasRelatedWork W1968988608 @default.
• W1968751925 hasRelatedWork W2071370076 @default.
• W1968751925 hasRelatedWork W2155653247 @default.
• W1968751925 hasRelatedWork W2161536338 @default.
• W1968751925 hasRelatedWork W2167911253 @default.
• W1968751925 hasRelatedWork W2754244034 @default.
• W1968751925 hasRelatedWork W2782212668 @default.
• W1968751925 hasRelatedWork W3092932241 @default.
• W1968751925 hasRelatedWork W3104531408 @default.

• next