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• W1968753921 endingPage "127" @default.
• W1968753921 startingPage "127" @default.
• W1968753921 abstract "Light represents an important environmental cue, which exerts considerable influence on the metabolism of fungi. Studies with the biotechnological fungal workhorse Trichoderma reesei (Hypocrea jecorina) have revealed an interconnection between transcriptional regulation of cellulolytic enzymes and the light response. Neurospora crassa has been used as a model organism to study light and circadian rhythm biology. We therefore investigated whether light also regulates transcriptional regulation of cellulolytic enzymes in N. crassa.We show that the N. crassa photoreceptor genes wc-1, wc-2 and vvd are involved in regulation of cellulase gene expression, indicating that this phenomenon is conserved among filamentous fungi. The negative effect of VVD on production of cellulolytic enzymes is thereby accomplished by its role in photoadaptation and hence its function in White collar complex (WCC) formation. In contrast, the induction of vvd expression by the WCC does not seem to be crucial in this process. Additionally, we found that WC-1 and WC-2 not only act as a complex, but also have individual functions upon growth on cellulose.Genome wide transcriptome analysis of photoreceptor mutants and evaluation of results by analysis of mutant strains identified several candidate genes likely to play a role in light modulated cellulase gene expression. Genes with functions in amino acid metabolism, glycogen metabolism, energy supply and protein folding are enriched among genes with decreased expression levels in the wc-1 and wc-2 mutants. The ability to properly respond to amino acid starvation, i. e. up-regulation of the cross pathway control protein cpc-1, was found to be beneficial for cellulase gene expression. Our results further suggest a contribution of oxidative depolymerization of cellulose to plant cell wall degradation in N. crassa." @default.
• W1968753921 created "2016-06-24" @default.
• W1968753921 creator A5003978738 @default.
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• W1968753921 creator A5053134006 @default.
• W1968753921 creator A5054440982 @default.
• W1968753921 creator A5056577532 @default.
• W1968753921 date "2012-01-01" @default.
• W1968753921 modified "2023-10-10" @default.
• W1968753921 title "Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa" @default.
• W1968753921 cites W1483509764 @default.
• W1968753921 cites W1496322705 @default.
• W1968753921 cites W1499336074 @default.
• W1968753921 cites W1521664071 @default.
• W1968753921 cites W1595932375 @default.
• W1968753921 cites W1599895431 @default.
• W1968753921 cites W1768392717 @default.
• W1968753921 cites W1873195519 @default.
• W1968753921 cites W1877233814 @default.
• W1968753921 cites W1945661233 @default.
• W1968753921 cites W1965107569 @default.
• W1968753921 cites W1967796434 @default.
• W1968753921 cites W1970463798 @default.
• W1968753921 cites W1976305103 @default.
• W1968753921 cites W1977064376 @default.
• W1968753921 cites W1979903188 @default.
• W1968753921 cites W1980988105 @default.
• W1968753921 cites W1983373264 @default.
• W1968753921 cites W1983982609 @default.
• W1968753921 cites W1995038206 @default.
• W1968753921 cites W1995939358 @default.
• W1968753921 cites W1997090665 @default.
• W1968753921 cites W1998820908 @default.
• W1968753921 cites W1999634015 @default.
• W1968753921 cites W2002123157 @default.
• W1968753921 cites W2004280561 @default.
• W1968753921 cites W2009495243 @default.
• W1968753921 cites W2011485738 @default.
• W1968753921 cites W2013859891 @default.
• W1968753921 cites W2017534621 @default.
• W1968753921 cites W2022339819 @default.
• W1968753921 cites W2022734245 @default.
• W1968753921 cites W2025019642 @default.
• W1968753921 cites W2025224575 @default.
• W1968753921 cites W2025817597 @default.
• W1968753921 cites W2028519434 @default.
• W1968753921 cites W2030470198 @default.
• W1968753921 cites W2032168472 @default.
• W1968753921 cites W2042068133 @default.
• W1968753921 cites W2050782835 @default.
• W1968753921 cites W2052476842 @default.
• W1968753921 cites W2052622825 @default.
• W1968753921 cites W2054599073 @default.
• W1968753921 cites W2055250487 @default.
• W1968753921 cites W2068346578 @default.
• W1968753921 cites W2071702322 @default.
• W1968753921 cites W2072766765 @default.
• W1968753921 cites W2073782662 @default.
• W1968753921 cites W2074303114 @default.
• W1968753921 cites W2082324597 @default.
• W1968753921 cites W2082591769 @default.
• W1968753921 cites W2082958905 @default.
• W1968753921 cites W2087280828 @default.
• W1968753921 cites W2096261603 @default.
• W1968753921 cites W2096732584 @default.
• W1968753921 cites W2099249565 @default.
• W1968753921 cites W2102142621 @default.
• W1968753921 cites W2105598099 @default.
• W1968753921 cites W2109924970 @default.
• W1968753921 cites W2112137033 @default.
• W1968753921 cites W2113134470 @default.
• W1968753921 cites W2114817244 @default.
• W1968753921 cites W2116236963 @default.
• W1968753921 cites W2118481109 @default.
• W1968753921 cites W2127017429 @default.
• W1968753921 cites W2127297472 @default.
• W1968753921 cites W2127500237 @default.
• W1968753921 cites W2130695937 @default.
• W1968753921 cites W2132089743 @default.
• W1968753921 cites W2132791239 @default.
• W1968753921 cites W2133076440 @default.
• W1968753921 cites W2133274717 @default.
• W1968753921 cites W2134236962 @default.
• W1968753921 cites W2136004844 @default.
• W1968753921 cites W2136464092 @default.
• W1968753921 cites W2136695668 @default.
• W1968753921 cites W2136730317 @default.
• W1968753921 cites W2137917513 @default.
• W1968753921 cites W2143108381 @default.
• W1968753921 cites W2145120518 @default.
• W1968753921 cites W2147022672 @default.
• W1968753921 cites W2155632794 @default.
• W1968753921 cites W2157407884 @default.
• W1968753921 cites W2158910355 @default.
• W1968753921 cites W2159384155 @default.
• W1968753921 cites W2160338568 @default.
• W1968753921 cites W2163685452 @default.
• W1968753921 cites W2163872057 @default.

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