Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968791566> ?p ?o ?g. }
- W1968791566 endingPage "e0117967" @default.
- W1968791566 startingPage "e0117967" @default.
- W1968791566 abstract "Intrinsically photosensitive retinal ganglion cells (ipRGCs) are involved in circadian and other non-image forming visual responses. An open question is whether the activity of these neurons may also be under the regulation mediated by the neurohormone melatonin. In the present work, by double-staining immunohistochemical technique, we studied the expression of MT1 and MT2, two known subtypes of mammalian melatonin receptors, in rat ipRGCs. A single subset of retinal ganglion cells labeled by the specific antibody against melanopsin exhibited the morphology typical of M1-type ipRGCs. Immunoreactivity for both MT1 and MT2 receptors was clearly seen in the cytoplasm of all labeled ipRGCs, indicating that these two receptors were co-expressed in each of these neurons. Furthermore, labeling for both the receptors were found in neonatal M1 cells as early as the day of birth. It is therefore highly plausible that retinal melatonin may directly modulate the activity of ipRGCs, thus regulating non-image forming visual functions." @default.
- W1968791566 created "2016-06-24" @default.
- W1968791566 creator A5044354699 @default.
- W1968791566 creator A5049272307 @default.
- W1968791566 creator A5057237564 @default.
- W1968791566 creator A5064495035 @default.
- W1968791566 creator A5068835449 @default.
- W1968791566 date "2015-02-25" @default.
- W1968791566 modified "2023-09-25" @default.
- W1968791566 title "Co-Expression of Two Subtypes of Melatonin Receptor on Rat M1-Type Intrinsically Photosensitive Retinal Ganglion Cells" @default.
- W1968791566 cites W147729479 @default.
- W1968791566 cites W1479926654 @default.
- W1968791566 cites W1488048016 @default.
- W1968791566 cites W1547324580 @default.
- W1968791566 cites W1560106330 @default.
- W1968791566 cites W1590907104 @default.
- W1968791566 cites W1766360407 @default.
- W1968791566 cites W1825366906 @default.
- W1968791566 cites W1963909077 @default.
- W1968791566 cites W1965542039 @default.
- W1968791566 cites W1968042048 @default.
- W1968791566 cites W1969540409 @default.
- W1968791566 cites W1971238746 @default.
- W1968791566 cites W1971524741 @default.
- W1968791566 cites W1971983064 @default.
- W1968791566 cites W1978178232 @default.
- W1968791566 cites W1980652986 @default.
- W1968791566 cites W1980693199 @default.
- W1968791566 cites W1981503145 @default.
- W1968791566 cites W1981996042 @default.
- W1968791566 cites W1983666444 @default.
- W1968791566 cites W1985201855 @default.
- W1968791566 cites W1985806794 @default.
- W1968791566 cites W1986596083 @default.
- W1968791566 cites W1986735688 @default.
- W1968791566 cites W1987179322 @default.
- W1968791566 cites W1987410085 @default.
- W1968791566 cites W1989189843 @default.
- W1968791566 cites W1995207708 @default.
- W1968791566 cites W1996384089 @default.
- W1968791566 cites W1996684193 @default.
- W1968791566 cites W1998822125 @default.
- W1968791566 cites W2003576389 @default.
- W1968791566 cites W2004990123 @default.
- W1968791566 cites W2006010108 @default.
- W1968791566 cites W2007395018 @default.
- W1968791566 cites W2009077913 @default.
- W1968791566 cites W2015324181 @default.
- W1968791566 cites W2021895129 @default.
- W1968791566 cites W2022197238 @default.
- W1968791566 cites W2022705005 @default.
- W1968791566 cites W2025288829 @default.
- W1968791566 cites W2026605955 @default.
- W1968791566 cites W2031626699 @default.
- W1968791566 cites W2034348289 @default.
- W1968791566 cites W2034416069 @default.
- W1968791566 cites W2035853180 @default.
- W1968791566 cites W2036239753 @default.
- W1968791566 cites W2038289966 @default.
- W1968791566 cites W2041499766 @default.
- W1968791566 cites W2042179612 @default.
- W1968791566 cites W2042890889 @default.
- W1968791566 cites W2043339068 @default.
- W1968791566 cites W2044447804 @default.
- W1968791566 cites W2045045758 @default.
- W1968791566 cites W2049690253 @default.
- W1968791566 cites W2049968846 @default.
- W1968791566 cites W2057279990 @default.
- W1968791566 cites W2058532346 @default.
- W1968791566 cites W2060132255 @default.
- W1968791566 cites W2065819455 @default.
- W1968791566 cites W2068015587 @default.
- W1968791566 cites W2068259240 @default.
- W1968791566 cites W2069342665 @default.
- W1968791566 cites W2075706037 @default.
- W1968791566 cites W2078090782 @default.
- W1968791566 cites W2087334106 @default.
- W1968791566 cites W2088406510 @default.
- W1968791566 cites W2091385411 @default.
- W1968791566 cites W2100123315 @default.
- W1968791566 cites W2116473569 @default.
- W1968791566 cites W2118563112 @default.
- W1968791566 cites W2126432711 @default.
- W1968791566 cites W2130821242 @default.
- W1968791566 cites W2136278225 @default.
- W1968791566 cites W2141029861 @default.
- W1968791566 cites W2142562918 @default.
- W1968791566 cites W2147949992 @default.
- W1968791566 cites W2159206020 @default.
- W1968791566 cites W2167010361 @default.
- W1968791566 cites W2411794422 @default.
- W1968791566 cites W4213205049 @default.
- W1968791566 cites W4313369757 @default.
- W1968791566 doi "https://doi.org/10.1371/journal.pone.0117967" @default.
- W1968791566 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4340921" @default.
- W1968791566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25714375" @default.
- W1968791566 hasPublicationYear "2015" @default.
- W1968791566 type Work @default.