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• W1968794095 abstract "Comparative study of the epidermis of lepidosaurian reptiles helps us to understand the formation of the shedding complex which determines epidermal shedding. The present ultrastructural study has analyzed the complete sequence of epidermal differentiation in the agamine lizard Physignatus lesueurii from 1 to 80 days post-hatching. Beneath a β-layer 20–40 layers of cells with an α-pattern of keratinization are produced, starting from narrow cells (mesos-like) followed gradually by typical thicker α-cells. At 80 days post-hatching an α-layer is still forming and the first epidermal shedding has still to take place. The differentiation of a shedding complex has been studied on the epidermis at 38 and 64 days of tail regeneration. Beneath the superficial regenerating (wound) epidermis, cells of the clear layer contain a meshwork of coarse and fibrous filaments which appear to turn into large keratohyalin-like granules. This extensive cytoskeleton may determine the progressive hardening of clear cells that function as a template for the formation of the large microornamentations of the underlying layer, a process that might be generalized for the genesis of microornamentations in all lepidosaurian reptiles. The microornamentations in Physignatus have a honey-comb pattern and are produced by the fusion between ‘oberhautchen” and β-cells. L'étude comparative de l'épiderme des reptiles lépidosauriens aide à comprendre la formation de la couche de scission qui va déterminer la mue. Cette étude analyse toute la séquence de différenciation épidermique du lézard AgamidéPhysignatus lesueurii, de 1 à 80 jours après l'éclosion. Sous la couche de β-kératine sont produites 20 à 40 couches de cellules de type α-kératine, en commençant par des cellules qui vont progressivement prendre l'aspect de cellules α-kératinisées. Quatre-vingt jours après l'éclosion, la couche se forme toujours et la première mue épidermique n'a pas encore commencé. Par ailleurs la differenciation de la couche de scission a été étudiée à 38–44 jours de régéneration de la queue. Sous le tissu épithélial de régénération superficielle, se trouve une couche de cellules claires contenant des filaments paraissant se rejoindre pour former des granules semblables à la kératohyaline. Ce cytosquelette étendu pourrait déterminer l'induration des cellules claires. Celles-ci pourraient agir comme une matrice dans la formation des grandes micro-ornementations des cellules sous-jacentes. Ce processus pourrait être commun à tous les reptiles lépidosauriens. Les micro-ornementations de Physignatus forment un dessin simple de forme hexagonale qui dérive de la fusion de l'oberautchen et de cellules à β-kératine." @default.
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• W1968794095 date "2000-01-01" @default.
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• W1968794095 title "Epidermal structure of normal and regenerating skin of the agamine lizard Physignatus lesueurii (McCoy, 1878) with emphasis on the formation of the shedding layer" @default.
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