FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968861569> ?p ?o ?g. }

• W1968861569 endingPage "65" @default.
• W1968861569 startingPage "60" @default.
• W1968861569 abstract "We demonstrated the expression of various exon-deleted progesterone receptor (PR) variant mRNAs in human uterine endometrial cancers using the reverse transcription-polymerase chain reaction-DNA sequencing analyses. In addition to PR wild-type mRNA, exon 4-deleted, exon 6-deleted, exon 3,4-deleted, exon 5,6-deleted, exon 4,5,6-deleted and exon 3,4,5,6-deleted PR variant mRNAs were identified. The exon 6-deleted and exon 5,6-deleted PR variant mRNAs lacked encoding for the steroid-binding domain. The exon 4-deleted, exon 3,4-deleted, exon 4,5,6-deleted and exon 3,4,5,6-deleted PR variant mRNAs lacked encoding for the DNA-binding domain in addition to encoding for the steroid-binding domain. While the exon 4-deleted, exon 6-deleted and exon 3,4-deleted PR variant mRNAs were observed in all samples analyzed, the exon 5,6-deleted, exon 4,5,6-deleted and/or exon 3,4,5,6-deleted PR variant mRNAs could not be detected in some cases, especially in poorly differentiated adenocarcinoma as compared with well-differentiated and moderately differentiated adenocarcinomas. The present study demonstrates the coexpression of PR exon-deleted variant mRNAs with the wild-type in uterine endometrial cancers. All translated variant proteins might possess functional diversity and might modify the progestational action of wild-type PR, and the expression of some PR variant mRNAs may be lost as endometrial cancer cells undergo dedifferentiation." @default.
• W1968861569 created "2016-06-24" @default.
• W1968861569 creator A5011264572 @default.
• W1968861569 creator A5024088812 @default.
• W1968861569 creator A5049922563 @default.
• W1968861569 creator A5089769400 @default.
• W1968861569 creator A5052693292 @default.
• W1968861569 creator A5076682762 @default.
• W1968861569 date "2000-01-01" @default.
• W1968861569 modified "2023-09-26" @default.
• W1968861569 title "Identification of Exon-Deleted Progesterone Receptor mRNAs in Human Uterine Endometrial Cancers" @default.
• W1968861569 cites W1510768805 @default.
• W1968861569 cites W1569704074 @default.
• W1968861569 cites W1587576181 @default.
• W1968861569 cites W1637034742 @default.
• W1968861569 cites W1969489572 @default.
• W1968861569 cites W1972931629 @default.
• W1968861569 cites W1982006286 @default.
• W1968861569 cites W1990374813 @default.
• W1968861569 cites W1996999531 @default.
• W1968861569 cites W1997194776 @default.
• W1968861569 cites W1997653383 @default.
• W1968861569 cites W1999143226 @default.
• W1968861569 cites W2010786524 @default.
• W1968861569 cites W2021942629 @default.
• W1968861569 cites W2033838368 @default.
• W1968861569 cites W2044869180 @default.
• W1968861569 cites W2050770488 @default.
• W1968861569 cites W2052552509 @default.
• W1968861569 cites W2055375920 @default.
• W1968861569 cites W2065524961 @default.
• W1968861569 cites W2076109054 @default.
• W1968861569 cites W2079593503 @default.
• W1968861569 cites W2093822539 @default.
• W1968861569 cites W2094891822 @default.
• W1968861569 cites W2112997731 @default.
• W1968861569 cites W2123793991 @default.
• W1968861569 cites W2129254256 @default.
• W1968861569 cites W2134812217 @default.
• W1968861569 cites W2157376240 @default.
• W1968861569 cites W1944697809 @default.
• W1968861569 doi "https://doi.org/10.1159/000012080" @default.
• W1968861569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10644942" @default.
• W1968861569 hasPublicationYear "2000" @default.
• W1968861569 type Work @default.
• W1968861569 sameAs 1968861569 @default.
• W1968861569 citedByCount "18" @default.
• W1968861569 countsByYear W19688615692013 @default.
• W1968861569 crossrefType "journal-article" @default.
• W1968861569 hasAuthorship W1968861569A5011264572 @default.
• W1968861569 hasAuthorship W1968861569A5024088812 @default.
• W1968861569 hasAuthorship W1968861569A5049922563 @default.
• W1968861569 hasAuthorship W1968861569A5052693292 @default.
• W1968861569 hasAuthorship W1968861569A5076682762 @default.
• W1968861569 hasAuthorship W1968861569A5089769400 @default.
• W1968861569 hasConcept C104317684 @default.
• W1968861569 hasConcept C121608353 @default.
• W1968861569 hasConcept C153911025 @default.
• W1968861569 hasConcept C156446351 @default.
• W1968861569 hasConcept C194583182 @default.
• W1968861569 hasConcept C36823959 @default.
• W1968861569 hasConcept C39917842 @default.
• W1968861569 hasConcept C530470458 @default.
• W1968861569 hasConcept C54355233 @default.
• W1968861569 hasConcept C84606932 @default.
• W1968861569 hasConcept C86803240 @default.
• W1968861569 hasConcept C98717036 @default.
• W1968861569 hasConceptScore W1968861569C104317684 @default.
• W1968861569 hasConceptScore W1968861569C121608353 @default.
• W1968861569 hasConceptScore W1968861569C153911025 @default.
• W1968861569 hasConceptScore W1968861569C156446351 @default.
• W1968861569 hasConceptScore W1968861569C194583182 @default.
• W1968861569 hasConceptScore W1968861569C36823959 @default.
• W1968861569 hasConceptScore W1968861569C39917842 @default.
• W1968861569 hasConceptScore W1968861569C530470458 @default.
• W1968861569 hasConceptScore W1968861569C54355233 @default.
• W1968861569 hasConceptScore W1968861569C84606932 @default.
• W1968861569 hasConceptScore W1968861569C86803240 @default.
• W1968861569 hasConceptScore W1968861569C98717036 @default.
• W1968861569 hasIssue "1" @default.
• W1968861569 hasLocation W19688615691 @default.
• W1968861569 hasLocation W19688615692 @default.
• W1968861569 hasOpenAccess W1968861569 @default.
• W1968861569 hasPrimaryLocation W19688615691 @default.
• W1968861569 hasRelatedWork W1968385908 @default.
• W1968861569 hasRelatedWork W2005929266 @default.
• W1968861569 hasRelatedWork W2006004944 @default.
• W1968861569 hasRelatedWork W2040290690 @default.
• W1968861569 hasRelatedWork W2052490065 @default.
• W1968861569 hasRelatedWork W2079921406 @default.
• W1968861569 hasRelatedWork W2087604594 @default.
• W1968861569 hasRelatedWork W2118812285 @default.
• W1968861569 hasRelatedWork W2468845670 @default.
• W1968861569 hasRelatedWork W3172156842 @default.
• W1968861569 hasVolume "58" @default.
• W1968861569 isParatext "false" @default.
• W1968861569 isRetracted "false" @default.
• W1968861569 magId "1968861569" @default.

• next