Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968883756> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1968883756 endingPage "171" @default.
- W1968883756 startingPage "162" @default.
- W1968883756 abstract "The glycoprotein nature of renin isolated from either rabbit or human kidney has been demonstrated by affinity chromatography on concanavalin A-Sepharose. The bulk of rabbit renin activity bound to concanavalin A is released by 20 to 50 mM α-methyl-d-mannoside. Adsorption of renin is prevented by periodate oxidation prior to chromatography. Mild acid treatment (pH 2.5) prior to chromatography does not alter the concanavalin A binding profile although the pI values of native rabbit renin (5.1–5.6) are shifted into a broader distribution (4.7–6.4). The molecular weight values of rabbit renin obtained by gel filtration and those from zone centrifugation are identical (37 000 ± 1000), consistent with a low percent of carbohydrate in the glycoprotein. A hydrophobic contribution to the binding of renin by concanavalin A is evident since, in the presence of mM Ca2+ and Mn2+, higher concentrations of α-methyl-d-mannoside are required to affect the same release of renin at 23 °C compared to that at 4 °C. Furthermore, 25% ethylene glycol releases renin in the absence of α-methyl-d-mannoside. It is concluded that renin contains a small number of carbohydrate residues in relatively close proximity to a hydrophobic surface which enhances the interaction with concanavalin A." @default.
- W1968883756 created "2016-06-24" @default.
- W1968883756 creator A5056018281 @default.
- W1968883756 creator A5072892481 @default.
- W1968883756 date "1977-09-01" @default.
- W1968883756 modified "2023-09-27" @default.
- W1968883756 title "Evidence for the glycoprotein nature of kidney renin" @default.
- W1968883756 cites W1513087030 @default.
- W1968883756 cites W1539207824 @default.
- W1968883756 cites W1569589672 @default.
- W1968883756 cites W1574862531 @default.
- W1968883756 cites W1611482599 @default.
- W1968883756 cites W1965318265 @default.
- W1968883756 cites W1970818884 @default.
- W1968883756 cites W1982611833 @default.
- W1968883756 cites W2013348493 @default.
- W1968883756 cites W2015150832 @default.
- W1968883756 cites W2044884327 @default.
- W1968883756 cites W2050413753 @default.
- W1968883756 cites W2054934176 @default.
- W1968883756 cites W2068898359 @default.
- W1968883756 cites W2079422209 @default.
- W1968883756 cites W2092880631 @default.
- W1968883756 cites W2092885332 @default.
- W1968883756 cites W2095116276 @default.
- W1968883756 cites W2099139884 @default.
- W1968883756 cites W2100635066 @default.
- W1968883756 cites W2105161964 @default.
- W1968883756 cites W2129979123 @default.
- W1968883756 cites W2134121439 @default.
- W1968883756 cites W2137302959 @default.
- W1968883756 cites W2162026081 @default.
- W1968883756 cites W2401681941 @default.
- W1968883756 cites W2409074056 @default.
- W1968883756 cites W2415817152 @default.
- W1968883756 doi "https://doi.org/10.1016/0005-2795(77)90144-1" @default.
- W1968883756 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/198005" @default.
- W1968883756 hasPublicationYear "1977" @default.
- W1968883756 type Work @default.
- W1968883756 sameAs 1968883756 @default.
- W1968883756 citedByCount "11" @default.
- W1968883756 crossrefType "journal-article" @default.
- W1968883756 hasAuthorship W1968883756A5056018281 @default.
- W1968883756 hasAuthorship W1968883756A5072892481 @default.
- W1968883756 hasConcept C108625454 @default.
- W1968883756 hasConcept C134018914 @default.
- W1968883756 hasConcept C178790620 @default.
- W1968883756 hasConcept C179247698 @default.
- W1968883756 hasConcept C181199279 @default.
- W1968883756 hasConcept C185592680 @default.
- W1968883756 hasConcept C193363816 @default.
- W1968883756 hasConcept C19869320 @default.
- W1968883756 hasConcept C198710026 @default.
- W1968883756 hasConcept C202751555 @default.
- W1968883756 hasConcept C2777516009 @default.
- W1968883756 hasConcept C2779881004 @default.
- W1968883756 hasConcept C2780091579 @default.
- W1968883756 hasConcept C43617362 @default.
- W1968883756 hasConcept C55493867 @default.
- W1968883756 hasConcept C84393581 @default.
- W1968883756 hasConcept C86803240 @default.
- W1968883756 hasConceptScore W1968883756C108625454 @default.
- W1968883756 hasConceptScore W1968883756C134018914 @default.
- W1968883756 hasConceptScore W1968883756C178790620 @default.
- W1968883756 hasConceptScore W1968883756C179247698 @default.
- W1968883756 hasConceptScore W1968883756C181199279 @default.
- W1968883756 hasConceptScore W1968883756C185592680 @default.
- W1968883756 hasConceptScore W1968883756C193363816 @default.
- W1968883756 hasConceptScore W1968883756C19869320 @default.
- W1968883756 hasConceptScore W1968883756C198710026 @default.
- W1968883756 hasConceptScore W1968883756C202751555 @default.
- W1968883756 hasConceptScore W1968883756C2777516009 @default.
- W1968883756 hasConceptScore W1968883756C2779881004 @default.
- W1968883756 hasConceptScore W1968883756C2780091579 @default.
- W1968883756 hasConceptScore W1968883756C43617362 @default.
- W1968883756 hasConceptScore W1968883756C55493867 @default.
- W1968883756 hasConceptScore W1968883756C84393581 @default.
- W1968883756 hasConceptScore W1968883756C86803240 @default.
- W1968883756 hasIssue "1" @default.
- W1968883756 hasLocation W19688837561 @default.
- W1968883756 hasLocation W19688837562 @default.
- W1968883756 hasOpenAccess W1968883756 @default.
- W1968883756 hasPrimaryLocation W19688837561 @default.
- W1968883756 hasRelatedWork W1968883756 @default.
- W1968883756 hasRelatedWork W1972300002 @default.
- W1968883756 hasRelatedWork W1991961087 @default.
- W1968883756 hasRelatedWork W2018306848 @default.
- W1968883756 hasRelatedWork W2036075900 @default.
- W1968883756 hasRelatedWork W2095276488 @default.
- W1968883756 hasRelatedWork W2133990946 @default.
- W1968883756 hasRelatedWork W2294584344 @default.
- W1968883756 hasRelatedWork W2349619096 @default.
- W1968883756 hasRelatedWork W70253686 @default.
- W1968883756 hasVolume "494" @default.
- W1968883756 isParatext "false" @default.
- W1968883756 isRetracted "false" @default.
- W1968883756 magId "1968883756" @default.
- W1968883756 workType "article" @default.