Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968924236> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1968924236 endingPage "722" @default.
- W1968924236 startingPage "715" @default.
- W1968924236 abstract "1. Radiolabelled diphenyl sulphoxide (U-14C- or 35S-) was administered by gavage (1.0 mmol kg body weight) to the adult male Wistar rat following an overnight fast. 2. For both labelled forms faeces was the major route of excretion of radioactivity (50%) with substantialamounts still being voided during the third and fourth days (13%). Urinary elimination (42%) was similar during the first (20%) and second (17%) days and a small amount of radioactivity (7%) was found within the carcass after 4 days. 3. Plasma data showed a peak concentration at 40 min (t) , a distribution half-life of max 2 h (t alpha) and an elimination half-life of 22.5 h (t beta). Biliary studies revealed that 16% of the dose traversed the bileduct duringthe first day withnearly half of this being excreted inthe first 8 h. 4. From urinary data, metabolism occurred via ring hydroxylation with subsequent conjugate formation. Oxidation of the sulphur to form the sulphone also took place. No evidence for sulphoxide reduction, cleavage of the ring structures or exclusion of the sulphur was obtained." @default.
- W1968924236 created "2016-06-24" @default.
- W1968924236 creator A5001516751 @default.
- W1968924236 creator A5017941988 @default.
- W1968924236 creator A5023993437 @default.
- W1968924236 creator A5047377881 @default.
- W1968924236 creator A5087849506 @default.
- W1968924236 creator A5088536388 @default.
- W1968924236 date "1998-01-01" @default.
- W1968924236 modified "2023-09-27" @default.
- W1968924236 title "Disposition of diphenyl sulphoxide in rat" @default.
- W1968924236 cites W1966275955 @default.
- W1968924236 cites W1973770584 @default.
- W1968924236 cites W2020123721 @default.
- W1968924236 cites W2024148060 @default.
- W1968924236 cites W2058873719 @default.
- W1968924236 cites W2093539962 @default.
- W1968924236 cites W2150043200 @default.
- W1968924236 cites W2326067073 @default.
- W1968924236 cites W2332777498 @default.
- W1968924236 cites W2339615941 @default.
- W1968924236 cites W1987905214 @default.
- W1968924236 doi "https://doi.org/10.1080/004982598239281" @default.
- W1968924236 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9711814" @default.
- W1968924236 hasPublicationYear "1998" @default.
- W1968924236 type Work @default.
- W1968924236 sameAs 1968924236 @default.
- W1968924236 citedByCount "0" @default.
- W1968924236 crossrefType "journal-article" @default.
- W1968924236 hasAuthorship W1968924236A5001516751 @default.
- W1968924236 hasAuthorship W1968924236A5017941988 @default.
- W1968924236 hasAuthorship W1968924236A5023993437 @default.
- W1968924236 hasAuthorship W1968924236A5047377881 @default.
- W1968924236 hasAuthorship W1968924236A5087849506 @default.
- W1968924236 hasAuthorship W1968924236A5088536388 @default.
- W1968924236 hasConcept C10146269 @default.
- W1968924236 hasConcept C112705442 @default.
- W1968924236 hasConcept C126322002 @default.
- W1968924236 hasConcept C134018914 @default.
- W1968924236 hasConcept C134306372 @default.
- W1968924236 hasConcept C151730666 @default.
- W1968924236 hasConcept C155647269 @default.
- W1968924236 hasConcept C181199279 @default.
- W1968924236 hasConcept C185592680 @default.
- W1968924236 hasConcept C197336794 @default.
- W1968924236 hasConcept C2780026642 @default.
- W1968924236 hasConcept C2781109383 @default.
- W1968924236 hasConcept C33923547 @default.
- W1968924236 hasConcept C3941253 @default.
- W1968924236 hasConcept C55493867 @default.
- W1968924236 hasConcept C61716771 @default.
- W1968924236 hasConcept C62231903 @default.
- W1968924236 hasConcept C71924100 @default.
- W1968924236 hasConcept C77411442 @default.
- W1968924236 hasConcept C86803240 @default.
- W1968924236 hasConceptScore W1968924236C10146269 @default.
- W1968924236 hasConceptScore W1968924236C112705442 @default.
- W1968924236 hasConceptScore W1968924236C126322002 @default.
- W1968924236 hasConceptScore W1968924236C134018914 @default.
- W1968924236 hasConceptScore W1968924236C134306372 @default.
- W1968924236 hasConceptScore W1968924236C151730666 @default.
- W1968924236 hasConceptScore W1968924236C155647269 @default.
- W1968924236 hasConceptScore W1968924236C181199279 @default.
- W1968924236 hasConceptScore W1968924236C185592680 @default.
- W1968924236 hasConceptScore W1968924236C197336794 @default.
- W1968924236 hasConceptScore W1968924236C2780026642 @default.
- W1968924236 hasConceptScore W1968924236C2781109383 @default.
- W1968924236 hasConceptScore W1968924236C33923547 @default.
- W1968924236 hasConceptScore W1968924236C3941253 @default.
- W1968924236 hasConceptScore W1968924236C55493867 @default.
- W1968924236 hasConceptScore W1968924236C61716771 @default.
- W1968924236 hasConceptScore W1968924236C62231903 @default.
- W1968924236 hasConceptScore W1968924236C71924100 @default.
- W1968924236 hasConceptScore W1968924236C77411442 @default.
- W1968924236 hasConceptScore W1968924236C86803240 @default.
- W1968924236 hasIssue "7" @default.
- W1968924236 hasLocation W19689242361 @default.
- W1968924236 hasLocation W19689242362 @default.
- W1968924236 hasOpenAccess W1968924236 @default.
- W1968924236 hasPrimaryLocation W19689242361 @default.
- W1968924236 hasRelatedWork W1484100502 @default.
- W1968924236 hasRelatedWork W1999077459 @default.
- W1968924236 hasRelatedWork W2042767146 @default.
- W1968924236 hasRelatedWork W2045937169 @default.
- W1968924236 hasRelatedWork W2073119156 @default.
- W1968924236 hasRelatedWork W2080675292 @default.
- W1968924236 hasRelatedWork W2081707388 @default.
- W1968924236 hasRelatedWork W2086777583 @default.
- W1968924236 hasRelatedWork W2139038320 @default.
- W1968924236 hasRelatedWork W2335060727 @default.
- W1968924236 hasVolume "28" @default.
- W1968924236 isParatext "false" @default.
- W1968924236 isRetracted "false" @default.
- W1968924236 magId "1968924236" @default.
- W1968924236 workType "article" @default.