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- W1968950192 abstract "Building upon the extensive work of many investigators it has been possible to develop a noninvasive technique to measure pulsatile arterial flow in the extremities. Changes in tissue volume were equated with changes in bioelectric impedance. A formula was derived in which the minute change in volume with each arterial pulse was defined in terms of impedance. The height of the impedance pulse wave, which closely resembles an arterial pressure wave, was used in this formula to calculate the resulting measurement of pulsatile arterial flow, defined as FLOWZ. This formula as well as the theory and technique were tested in two differentin vitro models and in multiple canine experiments. Comparisons made with arterial flow had correlation coefficients, which were consistently greater than 0.9. Bioelectric impedance measurements are sensitive to time-dependent volumetric changes only. The change in impedance with each arterial pulse is the integral of the difference between input and output flows. Total flow cannot be measured. Even the venous occlusion techniques, applicable to impedance as well as to the mechanical plethysmograh, alter vascular tone or resistance and hence, distort the normal flow [2]. Nevertheless, it is the relative change in blood flow rather than the absolute values of flow that is important in the bedside evaluation of a patient. This technique could be very helpful clinically, particularly in peripheral vascular disease." @default.
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- W1968950192 date "1973-07-01" @default.
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- W1968950192 title "Application of bioelectric impedance to the measurement of arterial flow" @default.
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- W1968950192 doi "https://doi.org/10.1016/0022-4804(73)90159-5" @default.
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