FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968967835> ?p ?o ?g. }

• W1968967835 endingPage "529" @default.
• W1968967835 startingPage "523" @default.
• W1968967835 abstract ": In this study factors are analyzed that may potentially influence the site of failure in pediatric medulloblastoma. Patient-related, disease-related, and treatment-related variables are analyzed with a special focus on radiotherapy time-dose and technical factors. : Eighty-six children and adolescents with a diagnosis of medulloblastoma were treated in Switzerland during the period 1972–1991. Postoperative megavoltage radiotherapy was delivered to all patients. Simulation and portal films of the whole-brain irradiation (WBI) fields were retrospectively reviewed in 77 carefully assessed and correlated with supratentorial failure-free survival. In 19 children the spine was treated with high-energy electron beams, the remainder with megavoltage photons. Simulation and port films of the posterior fossa fields were also reviewed in 72 patients. The field size and the field limits were evaluated and correlated with posterior fossa failure-free survival. : In 36 patients (47%) the WBI margins were judged to miss the inferior portion of the frontal and temporal lobes. Twelve patients failed in the supratentorial region and 9 of these patients belonged to the group of 36 children in whom the inferior portion of the brain had been underdosed. On multivariate analysis only field correctness was retained as being significantly correlated with supratentorial failure-free survival (p = 0.049). Neither and total dose to the spinal theca nor the treatment technique (electron vs. photon beams) were significantly correlated with outcome. Posterior fossa failure-free survival was not influenced by total dose, overall treatment time, field size, or field margin correctness. Overall survival was not influenced by any of the radiotherapy-related technical factors. : A correlation between WBI field correctness and supratentorial failure-free survival was observed. Treatment protocols should be considered that limit supratentorial irradiation mainly to subsites at highest risk of relapse. Optimized conformal therapy or proton beam therapy may help to reach this goal. Treating the spine with electron beams was not detereous. A significant correlation between local control and other technical factors was not observed, including those relating to posterior fossa treatment. The use of small conformal tumor bed boost fields may be prefered to the larger posterior fossa fields usually considered as the standard treatment approach." @default.
• W1968967835 created "2016-06-24" @default.
• W1968967835 creator A5006149096 @default.
• W1968967835 creator A5015539696 @default.
• W1968967835 creator A5026670636 @default.
• W1968967835 creator A5027385492 @default.
• W1968967835 creator A5041660589 @default.
• W1968967835 creator A5042125479 @default.
• W1968967835 creator A5047908939 @default.
• W1968967835 creator A5064875862 @default.
• W1968967835 creator A5077548663 @default.
• W1968967835 creator A5082119626 @default.
• W1968967835 creator A5090608663 @default.
• W1968967835 date "1997-02-01" @default.
• W1968967835 modified "2023-10-14" @default.
• W1968967835 title "Pediatric medulloblastoma: Radiation treatment technique and patterns of failure" @default.
• W1968967835 cites W1964202387 @default.
• W1968967835 cites W1977826988 @default.
• W1968967835 cites W1978161696 @default.
• W1968967835 cites W1985331426 @default.
• W1968967835 cites W1986557288 @default.
• W1968967835 cites W1991001694 @default.
• W1968967835 cites W1997501131 @default.
• W1968967835 cites W2004166807 @default.
• W1968967835 cites W2006755529 @default.
• W1968967835 cites W2007803784 @default.
• W1968967835 cites W2012157462 @default.
• W1968967835 cites W2030325217 @default.
• W1968967835 cites W2041759695 @default.
• W1968967835 cites W2062033425 @default.
• W1968967835 cites W2069010139 @default.
• W1968967835 cites W2081678284 @default.
• W1968967835 cites W2120098513 @default.
• W1968967835 cites W2128814737 @default.
• W1968967835 cites W2133893515 @default.
• W1968967835 cites W2156869994 @default.
• W1968967835 doi "https://doi.org/10.1016/s0360-3016(96)00569-x" @default.
• W1968967835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9112448" @default.
• W1968967835 hasPublicationYear "1997" @default.
• W1968967835 type Work @default.
• W1968967835 sameAs 1968967835 @default.
• W1968967835 citedByCount "94" @default.
• W1968967835 countsByYear W19689678352012 @default.
• W1968967835 countsByYear W19689678352013 @default.
• W1968967835 countsByYear W19689678352014 @default.
• W1968967835 countsByYear W19689678352015 @default.
• W1968967835 countsByYear W19689678352016 @default.
• W1968967835 countsByYear W19689678352017 @default.
• W1968967835 countsByYear W19689678352018 @default.
• W1968967835 countsByYear W19689678352019 @default.
• W1968967835 countsByYear W19689678352020 @default.
• W1968967835 countsByYear W19689678352021 @default.
• W1968967835 countsByYear W19689678352022 @default.
• W1968967835 countsByYear W19689678352023 @default.
• W1968967835 crossrefType "journal-article" @default.
• W1968967835 hasAuthorship W1968967835A5006149096 @default.
• W1968967835 hasAuthorship W1968967835A5015539696 @default.
• W1968967835 hasAuthorship W1968967835A5026670636 @default.
• W1968967835 hasAuthorship W1968967835A5027385492 @default.
• W1968967835 hasAuthorship W1968967835A5041660589 @default.
• W1968967835 hasAuthorship W1968967835A5042125479 @default.
• W1968967835 hasAuthorship W1968967835A5047908939 @default.
• W1968967835 hasAuthorship W1968967835A5064875862 @default.
• W1968967835 hasAuthorship W1968967835A5077548663 @default.
• W1968967835 hasAuthorship W1968967835A5082119626 @default.
• W1968967835 hasAuthorship W1968967835A5090608663 @default.
• W1968967835 hasConcept C126838900 @default.
• W1968967835 hasConcept C141071460 @default.
• W1968967835 hasConcept C142724271 @default.
• W1968967835 hasConcept C2780789225 @default.
• W1968967835 hasConcept C2989005 @default.
• W1968967835 hasConcept C509974204 @default.
• W1968967835 hasConcept C71924100 @default.
• W1968967835 hasConceptScore W1968967835C126838900 @default.
• W1968967835 hasConceptScore W1968967835C141071460 @default.
• W1968967835 hasConceptScore W1968967835C142724271 @default.
• W1968967835 hasConceptScore W1968967835C2780789225 @default.
• W1968967835 hasConceptScore W1968967835C2989005 @default.
• W1968967835 hasConceptScore W1968967835C509974204 @default.
• W1968967835 hasConceptScore W1968967835C71924100 @default.
• W1968967835 hasIssue "3" @default.
• W1968967835 hasLocation W19689678351 @default.
• W1968967835 hasLocation W19689678352 @default.
• W1968967835 hasOpenAccess W1968967835 @default.
• W1968967835 hasPrimaryLocation W19689678351 @default.
• W1968967835 hasRelatedWork W2002120878 @default.
• W1968967835 hasRelatedWork W2003938723 @default.
• W1968967835 hasRelatedWork W2047967234 @default.
• W1968967835 hasRelatedWork W2118496982 @default.
• W1968967835 hasRelatedWork W2364998975 @default.
• W1968967835 hasRelatedWork W2369162477 @default.
• W1968967835 hasRelatedWork W2439875401 @default.
• W1968967835 hasRelatedWork W4238867864 @default.
• W1968967835 hasRelatedWork W2519357708 @default.
• W1968967835 hasRelatedWork W2525756941 @default.
• W1968967835 hasVolume "37" @default.
• W1968967835 isParatext "false" @default.
• W1968967835 isRetracted "false" @default.

• next