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- W1968971556 abstract "Prostaglandin E2 and F2α were measured in ejaculates from 10 fertile and 55 infertile men. Prostaglandin F2α was negatively correlated with motility (r=0.77; p<0.01) in normal men. In patients with disturbed fertility, prostaglandin F2α was always higher than in the controls, while prostaglandin E2 was elevated only in patients with persisting varicocele and in those with very low sperm counts and severely impaired motility. There was neither de novo synthesis of prostaglandins in spermatozoa nor were binding sites for prostaglandin E2 and F2α detectable. Inactivation of seminal prostaglandins by incubation with prostaglandin 15-hydroxydehydrogenase resulted in a dramatic fall in motility. The results suggest that prostaglandin F2α act on motility, but the action is not mediated by receptors." @default.
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- W1968971556 date "1981-01-01" @default.
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- W1968971556 title "The influence of prostaglandins on sperm motility" @default.
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- W1968971556 doi "https://doi.org/10.1016/0090-6980(81)90199-4" @default.
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