Matches in SemOpenAlex for { <https://semopenalex.org/work/W1968989893> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W1968989893 abstract "Adult male rats were implanted with chronically indwelling recording electrodes in the dentate hilus of one hemisphere and bipolar stimulating electrodes in the contralateral entorhinal cortex (EC). Daily measurements were then made of the amplitude of responses, evoked through the crossed temporodentate (CTD) pathway, while the rats were unanesthetized and unrestrained. The implanted rats were also trained to alternate turns in a T-maze, with the use of a rewarded-alternation procedure. After reaching criterion performance in the alternation task, each rat was given a lesion of the EC ipsilateral to the recording electrode (n = 14) or a sham lesion (n = 5). Mean amplitudes of the evoked responses increased over Postlesion Days 4-11, probably due to reactive synaptogenesis in the CTD system, reaching a level that was significantly elevated above prelesion levels by Postlesion Day 6. Rats given EC lesions exhibited a transient impairment in alternation performance, with the mean alternation score significantly below prelesion levels on Postlesion Days 2-6. Although 2 EC-lesioned rats did not show a behavioral deficit, the electrophysiological increases and behavioral recovery were correlated in the remaining 12 cases (Pearson r = .73). These results are consistent with the interpretation that sprouting by the CTD system contributes to recovery of T-maze alternation performance following unilateral EC lesions." @default.
- W1968989893 created "2016-06-24" @default.
- W1968989893 creator A5032091625 @default.
- W1968989893 creator A5051240975 @default.
- W1968989893 date "1987-01-01" @default.
- W1968989893 modified "2023-09-25" @default.
- W1968989893 title "Reinnervation of the dentate gyrus and recovery of alternation behavior following entorhinal cortex lesions." @default.
- W1968989893 cites W2134654456 @default.
- W1968989893 cites W2163815564 @default.
- W1968989893 doi "https://doi.org/10.1037//0735-7044.101.2.179" @default.
- W1968989893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3580120" @default.
- W1968989893 hasPublicationYear "1987" @default.
- W1968989893 type Work @default.
- W1968989893 sameAs 1968989893 @default.
- W1968989893 citedByCount "27" @default.
- W1968989893 countsByYear W19689898932014 @default.
- W1968989893 countsByYear W19689898932016 @default.
- W1968989893 crossrefType "journal-article" @default.
- W1968989893 hasAuthorship W1968989893A5032091625 @default.
- W1968989893 hasAuthorship W1968989893A5051240975 @default.
- W1968989893 hasConcept C138885662 @default.
- W1968989893 hasConcept C142724271 @default.
- W1968989893 hasConcept C15744967 @default.
- W1968989893 hasConcept C169760540 @default.
- W1968989893 hasConcept C185263204 @default.
- W1968989893 hasConcept C26826806 @default.
- W1968989893 hasConcept C2775847253 @default.
- W1968989893 hasConcept C2776464000 @default.
- W1968989893 hasConcept C2780715579 @default.
- W1968989893 hasConcept C2781156865 @default.
- W1968989893 hasConcept C2781161787 @default.
- W1968989893 hasConcept C41895202 @default.
- W1968989893 hasConcept C65232495 @default.
- W1968989893 hasConcept C71924100 @default.
- W1968989893 hasConceptScore W1968989893C138885662 @default.
- W1968989893 hasConceptScore W1968989893C142724271 @default.
- W1968989893 hasConceptScore W1968989893C15744967 @default.
- W1968989893 hasConceptScore W1968989893C169760540 @default.
- W1968989893 hasConceptScore W1968989893C185263204 @default.
- W1968989893 hasConceptScore W1968989893C26826806 @default.
- W1968989893 hasConceptScore W1968989893C2775847253 @default.
- W1968989893 hasConceptScore W1968989893C2776464000 @default.
- W1968989893 hasConceptScore W1968989893C2780715579 @default.
- W1968989893 hasConceptScore W1968989893C2781156865 @default.
- W1968989893 hasConceptScore W1968989893C2781161787 @default.
- W1968989893 hasConceptScore W1968989893C41895202 @default.
- W1968989893 hasConceptScore W1968989893C65232495 @default.
- W1968989893 hasConceptScore W1968989893C71924100 @default.
- W1968989893 hasLocation W19689898931 @default.
- W1968989893 hasLocation W19689898932 @default.
- W1968989893 hasOpenAccess W1968989893 @default.
- W1968989893 hasPrimaryLocation W19689898931 @default.
- W1968989893 hasRelatedWork W1937721229 @default.
- W1968989893 hasRelatedWork W1968989893 @default.
- W1968989893 hasRelatedWork W1990458657 @default.
- W1968989893 hasRelatedWork W1991625887 @default.
- W1968989893 hasRelatedWork W1996408686 @default.
- W1968989893 hasRelatedWork W1998639678 @default.
- W1968989893 hasRelatedWork W2050131805 @default.
- W1968989893 hasRelatedWork W2056422991 @default.
- W1968989893 hasRelatedWork W2065365265 @default.
- W1968989893 hasRelatedWork W2793594670 @default.
- W1968989893 isParatext "false" @default.
- W1968989893 isRetracted "false" @default.
- W1968989893 magId "1968989893" @default.
- W1968989893 workType "article" @default.