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- W1969008840 abstract "1. The activities and cellular distribution of the tricarboxylic acid cycle enzymes; citrate synthase, aconitase, isocitrate dehydrogenase, α-oxoglutarate dehydrogenase, succinate dehydrogenase, fumarase, malate dehydrogenase, and glutamate dehydrogenase were determined in Fasciola hepatica and rat liver. 2. The coenzyme specificities of isocitrate dehydrogenase and glutamate dehydrogenase were determined for both tissues. 3. Aconitase and fumarase activities could not be detected in the mitochondrial fraction from F. hepatica, while NAD-specific isocitrate dehydrogenase could not be detected in either the mitochondrial or supernatant fraction from this tissue. 4. Succinate dehydrogenase activity was determined in both reaction direction in F. hepatica and rat liver. The oxidation of NADH2 with fumarate was demonstrated in F. hepatica mitochondria under aerobic conditions. 5. The low levels of aconitase and NADP-specific isocitrate dehydrogenase and the absence of NAD-specific isocitrate dehydrogenase suggest that the tricarboxylic acid cycle may be of minor importance in F. hepatica." @default.
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- W1969008840 date "1968-06-01" @default.
- W1969008840 modified "2023-09-25" @default.
- W1969008840 title "A comparative study of the tricarboxylic acid cycle enzymes in Fasciola hepatica and rat liver" @default.
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- W1969008840 doi "https://doi.org/10.1016/0010-406x(68)90587-2" @default.
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