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- W1969021253 abstract "The discovery and synthesis of a series of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A2A receptor antagonists from a small-molecule combinatorial library using a high-throughput radioligand-binding assay is described. Antagonists were further characterized in the A2A binding assay and an A1 selectivity assay. Selected examples exhibited excellent affinity for A2A and good selectivity versus the A1 receptor." @default.
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- W1969021253 date "2009-01-01" @default.
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- W1969021253 title "Synthesis of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A2A receptor antagonists" @default.
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- W1969021253 doi "https://doi.org/10.1016/j.bmcl.2008.11.066" @default.
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