FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969040012> ?p ?o ?g. }

• W1969040012 endingPage "5996" @default.
• W1969040012 startingPage "5993" @default.
• W1969040012 abstract "An increasing body of evidence has suggested trophic effects of peripheral nerves. In this study, the growth stimulatory properties of the sensory neuropeptides vasoactive intestinal polypeptide (VIP), substance P (SP), calcitonin generelated peptide (CGRP), and somatostatin (SOM) on cultured human keratinocytes were investigated. It was shown that VIP, in the presence of lethally treated 3T3 fibroblast feeder cells and epidermal growth factor (EGF), stimulated proliferation of keratinocytes in a dose-dependent manner, whereas SP, CGRP, and SOM were ineffective. VIP stimulated adenylate cyclase activity in membranes obtained from cultured keratinocytes in a dose-dependent manner, indicating an involvement of cAMP as second messenger in this reaction. Furthermore, 125I-labeled VIP was shown to bind to cultured keratinocytes and this binding could be displaced by addition of unlabeled VIP, suggesting the presence of specific receptors. It is therefore possible that VIP, released from sensory nerve endings in the skin, may act as a local mitogenic factor for human keratinocytes by stimulating adenylate cyclase activity via specific VIP receptors." @default.
• W1969040012 created "2016-06-24" @default.
• W1969040012 creator A5021276063 @default.
• W1969040012 creator A5044969624 @default.
• W1969040012 creator A5089621510 @default.
• W1969040012 creator A5091555354 @default.
• W1969040012 date "1989-08-01" @default.
• W1969040012 modified "2023-10-18" @default.
• W1969040012 title "Vasoactive intestinal polypeptide stimulates cell proliferation and adenylate cyclase activity of cultured human keratinocytes." @default.
• W1969040012 cites W1647422859 @default.
• W1969040012 cites W1703816965 @default.
• W1969040012 cites W1968549810 @default.
• W1969040012 cites W1968858188 @default.
• W1969040012 cites W1970995332 @default.
• W1969040012 cites W1979360064 @default.
• W1969040012 cites W2007563990 @default.
• W1969040012 cites W2015361707 @default.
• W1969040012 cites W2016785445 @default.
• W1969040012 cites W2023384348 @default.
• W1969040012 cites W2031956553 @default.
• W1969040012 cites W2032350393 @default.
• W1969040012 cites W2036515731 @default.
• W1969040012 cites W2038579881 @default.
• W1969040012 cites W2042629233 @default.
• W1969040012 cites W2045041512 @default.
• W1969040012 cites W2045580584 @default.
• W1969040012 cites W2048503962 @default.
• W1969040012 cites W2050453095 @default.
• W1969040012 cites W2056971358 @default.
• W1969040012 cites W2059022474 @default.
• W1969040012 cites W2060545178 @default.
• W1969040012 cites W2064504925 @default.
• W1969040012 cites W2069853132 @default.
• W1969040012 cites W2074539095 @default.
• W1969040012 cites W2078168842 @default.
• W1969040012 cites W2078548333 @default.
• W1969040012 cites W2135190507 @default.
• W1969040012 cites W2318773134 @default.
• W1969040012 cites W2321548031 @default.
• W1969040012 cites W2413738085 @default.
• W1969040012 doi "https://doi.org/10.1073/pnas.86.15.5993" @default.
• W1969040012 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/297758" @default.
• W1969040012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2474824" @default.
• W1969040012 hasPublicationYear "1989" @default.
• W1969040012 type Work @default.
• W1969040012 sameAs 1969040012 @default.
• W1969040012 citedByCount "153" @default.
• W1969040012 countsByYear W19690400122012 @default.
• W1969040012 countsByYear W19690400122017 @default.
• W1969040012 countsByYear W19690400122019 @default.
• W1969040012 countsByYear W19690400122020 @default.
• W1969040012 countsByYear W19690400122021 @default.
• W1969040012 countsByYear W19690400122022 @default.
• W1969040012 countsByYear W19690400122023 @default.
• W1969040012 crossrefType "journal-article" @default.
• W1969040012 hasAuthorship W1969040012A5021276063 @default.
• W1969040012 hasAuthorship W1969040012A5044969624 @default.
• W1969040012 hasAuthorship W1969040012A5089621510 @default.
• W1969040012 hasAuthorship W1969040012A5091555354 @default.
• W1969040012 hasBestOaLocation W19690400122 @default.
• W1969040012 hasConcept C118303440 @default.
• W1969040012 hasConcept C126322002 @default.
• W1969040012 hasConcept C134018914 @default.
• W1969040012 hasConcept C163170386 @default.
• W1969040012 hasConcept C163235415 @default.
• W1969040012 hasConcept C170493617 @default.
• W1969040012 hasConcept C180526460 @default.
• W1969040012 hasConcept C185592680 @default.
• W1969040012 hasConcept C2776297358 @default.
• W1969040012 hasConcept C2776362946 @default.
• W1969040012 hasConcept C2779627488 @default.
• W1969040012 hasConcept C2780069284 @default.
• W1969040012 hasConcept C55493867 @default.
• W1969040012 hasConcept C71924100 @default.
• W1969040012 hasConcept C8330315 @default.
• W1969040012 hasConcept C86803240 @default.
• W1969040012 hasConceptScore W1969040012C118303440 @default.
• W1969040012 hasConceptScore W1969040012C126322002 @default.
• W1969040012 hasConceptScore W1969040012C134018914 @default.
• W1969040012 hasConceptScore W1969040012C163170386 @default.
• W1969040012 hasConceptScore W1969040012C163235415 @default.
• W1969040012 hasConceptScore W1969040012C170493617 @default.
• W1969040012 hasConceptScore W1969040012C180526460 @default.
• W1969040012 hasConceptScore W1969040012C185592680 @default.
• W1969040012 hasConceptScore W1969040012C2776297358 @default.
• W1969040012 hasConceptScore W1969040012C2776362946 @default.
• W1969040012 hasConceptScore W1969040012C2779627488 @default.
• W1969040012 hasConceptScore W1969040012C2780069284 @default.
• W1969040012 hasConceptScore W1969040012C55493867 @default.
• W1969040012 hasConceptScore W1969040012C71924100 @default.
• W1969040012 hasConceptScore W1969040012C8330315 @default.
• W1969040012 hasConceptScore W1969040012C86803240 @default.
• W1969040012 hasIssue "15" @default.
• W1969040012 hasLocation W19690400121 @default.
• W1969040012 hasLocation W19690400122 @default.
• W1969040012 hasLocation W19690400123 @default.
• W1969040012 hasLocation W19690400124 @default.
• W1969040012 hasOpenAccess W1969040012 @default.

• next