FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969055364> ?p ?o ?g. }

• W1969055364 endingPage "74" @default.
• W1969055364 startingPage "61" @default.
• W1969055364 abstract "AbstractThree-dimensional oriented chitosan (CS)/hydroxyapatite (HA) scaffolds were prepared via in situ precipitation method in this research. Scanning electron microscopy (SEM) images indicated that the scaffolds with acicular nano-HA had the spoke-like, multilayer and porous structure. The SEM of osteoblasts which were polygonal or spindle-shaped on the composite scaffolds after seven-day cell culture showed that the cells grew, adhered, and spread well. The results of X-ray powder diffractometer and Fourier transform infrared spectrometer showed that the mineral particles deposited in the scaffold had phase structure similar to natural bone and confirmed that particles were exactly HA. In vitro biocompatibility evaluation indicated the composite scaffolds showed a higher degree of proliferation of MC3T3-E1 cell compared with the pure CS scaffolds and the CS/HA10 scaffold was the highest one. The CS/HA scaffold also had a higher ratio of adhesion and alkaline phosphate activity value of osteoblasts compared with the pure CS scaffold, and the ratio increased with the increase of HA content. The ALP activity value of composite scaffolds was at least six times of the pure CS scaffolds. The results suggested that the composite scaffolds possessed good biocompatibility. The compressive strength of CS/HA15 increased by 33.07% compared with the pure CS scaffold. This novel porous scaffold with three-dimensional oriented structure might have a potential application in bone tissue engineering.Keywords: chitosanhydroxyapatitethree-dimensional oriented scaffoldbone tissue engineeringin situ precipitation FundingThis work was partially funded by National Natural Science Foundation of China [Grant Nos. 21104067 and 21274127], the Key Basic Research Development Plan (Project 973) of China [Grant Nos. 2011CB606203 and 2009CB930104], Grand Science and Technology Special Project of Zhejiang Province [Grant No. 2008C11087], and Fundamental Research Funds for the Central 20 Universities (2013QNA4048)." @default.
• W1969055364 created "2016-06-24" @default.
• W1969055364 creator A5008716352 @default.
• W1969055364 creator A5013778882 @default.
• W1969055364 creator A5026477159 @default.
• W1969055364 creator A5033922885 @default.
• W1969055364 creator A5053152570 @default.
• W1969055364 creator A5062353883 @default.
• W1969055364 date "2013-09-23" @default.
• W1969055364 modified "2023-10-09" @default.
• W1969055364 title "Preparation and characterization of bionic bone structure chitosan/hydroxyapatite scaffold for bone tissue engineering" @default.
• W1969055364 cites W1971142659 @default.
• W1969055364 cites W1976221789 @default.
• W1969055364 cites W1987190449 @default.
• W1969055364 cites W1988109470 @default.
• W1969055364 cites W1998061495 @default.
• W1969055364 cites W1998454830 @default.
• W1969055364 cites W2001377295 @default.
• W1969055364 cites W2001829056 @default.
• W1969055364 cites W2011557430 @default.
• W1969055364 cites W2016283187 @default.
• W1969055364 cites W2016346790 @default.
• W1969055364 cites W2020358908 @default.
• W1969055364 cites W2021790237 @default.
• W1969055364 cites W2038872961 @default.
• W1969055364 cites W2039862234 @default.
• W1969055364 cites W2043649321 @default.
• W1969055364 cites W2049341890 @default.
• W1969055364 cites W2057723544 @default.
• W1969055364 cites W2058467317 @default.
• W1969055364 cites W2061753360 @default.
• W1969055364 cites W2064798085 @default.
• W1969055364 cites W2065976474 @default.
• W1969055364 cites W2079158469 @default.
• W1969055364 cites W2081071640 @default.
• W1969055364 cites W2090836893 @default.
• W1969055364 cites W2095302268 @default.
• W1969055364 cites W2104948210 @default.
• W1969055364 cites W2114260548 @default.
• W1969055364 cites W2159210886 @default.
• W1969055364 doi "https://doi.org/10.1080/09205063.2013.836950" @default.
• W1969055364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24053536" @default.
• W1969055364 hasPublicationYear "2013" @default.
• W1969055364 type Work @default.
• W1969055364 sameAs 1969055364 @default.
• W1969055364 citedByCount "64" @default.
• W1969055364 countsByYear W19690553642014 @default.
• W1969055364 countsByYear W19690553642015 @default.
• W1969055364 countsByYear W19690553642016 @default.
• W1969055364 countsByYear W19690553642017 @default.
• W1969055364 countsByYear W19690553642018 @default.
• W1969055364 countsByYear W19690553642019 @default.
• W1969055364 countsByYear W19690553642020 @default.
• W1969055364 countsByYear W19690553642021 @default.
• W1969055364 countsByYear W19690553642022 @default.
• W1969055364 countsByYear W19690553642023 @default.
• W1969055364 crossrefType "journal-article" @default.
• W1969055364 hasAuthorship W1969055364A5008716352 @default.
• W1969055364 hasAuthorship W1969055364A5013778882 @default.
• W1969055364 hasAuthorship W1969055364A5026477159 @default.
• W1969055364 hasAuthorship W1969055364A5033922885 @default.
• W1969055364 hasAuthorship W1969055364A5053152570 @default.
• W1969055364 hasAuthorship W1969055364A5062353883 @default.
• W1969055364 hasConcept C104779481 @default.
• W1969055364 hasConcept C127413603 @default.
• W1969055364 hasConcept C136229726 @default.
• W1969055364 hasConcept C159985019 @default.
• W1969055364 hasConcept C178790620 @default.
• W1969055364 hasConcept C185592680 @default.
• W1969055364 hasConcept C191897082 @default.
• W1969055364 hasConcept C192562407 @default.
• W1969055364 hasConcept C26771246 @default.
• W1969055364 hasConcept C2777230088 @default.
• W1969055364 hasConcept C2779732960 @default.
• W1969055364 hasConcept C30407753 @default.
• W1969055364 hasConcept C39546656 @default.
• W1969055364 hasConcept C42360764 @default.
• W1969055364 hasConcept C49892992 @default.
• W1969055364 hasConcept C71924100 @default.
• W1969055364 hasConcept C89429830 @default.
• W1969055364 hasConceptScore W1969055364C104779481 @default.
• W1969055364 hasConceptScore W1969055364C127413603 @default.
• W1969055364 hasConceptScore W1969055364C136229726 @default.
• W1969055364 hasConceptScore W1969055364C159985019 @default.
• W1969055364 hasConceptScore W1969055364C178790620 @default.
• W1969055364 hasConceptScore W1969055364C185592680 @default.
• W1969055364 hasConceptScore W1969055364C191897082 @default.
• W1969055364 hasConceptScore W1969055364C192562407 @default.
• W1969055364 hasConceptScore W1969055364C26771246 @default.
• W1969055364 hasConceptScore W1969055364C2777230088 @default.
• W1969055364 hasConceptScore W1969055364C2779732960 @default.
• W1969055364 hasConceptScore W1969055364C30407753 @default.
• W1969055364 hasConceptScore W1969055364C39546656 @default.
• W1969055364 hasConceptScore W1969055364C42360764 @default.
• W1969055364 hasConceptScore W1969055364C49892992 @default.
• W1969055364 hasConceptScore W1969055364C71924100 @default.
• W1969055364 hasConceptScore W1969055364C89429830 @default.
• W1969055364 hasIssue "1" @default.

• next