Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969099992> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1969099992 endingPage "725" @default.
- W1969099992 startingPage "722" @default.
- W1969099992 abstract "Many small RNAs contribute essential activities to eukaryotic cells. In mammalian genomes dispersed repetitive sequences which exhibit homology to small RNAs often exist as pseudogenes which can complicate identification, localization, and analysis of the authentic gene. We mapped a productive human 7SK small nuclear RNA gene to human chromosome 6 by analyzing Northern blots derived from a panel of somatic cell hybrids that contain single human chromosomes. In order to avoid crossreactlvity of the probe with rodent 7SK RNA, which Is 98% Identical to human 7SK, a method termed homolog exclusion probing was developed. This method uses an excess of non-labelled rodent-specific oligodeoxynucleotlde to block the rodent 7SK RNA from hybridizing with the human-specific oligodeoxynucleotlde probe. The effectiveness of this method to enhance the human 7SK RNA signal is demonstrated. The potential to map and subsequently isolate other small RNA genes by this approach and the use of homolog exclusion probing to discriminate among family members of highly related RNAs and DNAs In a single species is discussed." @default.
- W1969099992 created "2016-06-24" @default.
- W1969099992 creator A5006376261 @default.
- W1969099992 creator A5006834012 @default.
- W1969099992 creator A5049076723 @default.
- W1969099992 date "1994-01-01" @default.
- W1969099992 modified "2023-09-24" @default.
- W1969099992 title "The conserved 7SK snRNA gene localizes to human chromosome 6 by homolog exclusion probing of somatic cell hybrid RNA" @default.
- W1969099992 cites W149933225 @default.
- W1969099992 cites W1537106366 @default.
- W1969099992 cites W1662064273 @default.
- W1969099992 cites W1878712318 @default.
- W1969099992 cites W1982977375 @default.
- W1969099992 cites W1983919067 @default.
- W1969099992 cites W1986404015 @default.
- W1969099992 cites W1992218856 @default.
- W1969099992 cites W1995936125 @default.
- W1969099992 cites W2000782186 @default.
- W1969099992 cites W2006405253 @default.
- W1969099992 cites W2012252163 @default.
- W1969099992 cites W2022149623 @default.
- W1969099992 cites W2059509189 @default.
- W1969099992 cites W2073395746 @default.
- W1969099992 cites W2084964666 @default.
- W1969099992 cites W2090513774 @default.
- W1969099992 cites W2092205160 @default.
- W1969099992 cites W2103973742 @default.
- W1969099992 cites W2119860285 @default.
- W1969099992 cites W240420952 @default.
- W1969099992 cites W4255036110 @default.
- W1969099992 doi "https://doi.org/10.1093/nar/22.5.722" @default.
- W1969099992 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/307874" @default.
- W1969099992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8139910" @default.
- W1969099992 hasPublicationYear "1994" @default.
- W1969099992 type Work @default.
- W1969099992 sameAs 1969099992 @default.
- W1969099992 citedByCount "6" @default.
- W1969099992 countsByYear W19690999922020 @default.
- W1969099992 countsByYear W19690999922023 @default.
- W1969099992 crossrefType "journal-article" @default.
- W1969099992 hasAuthorship W1969099992A5006376261 @default.
- W1969099992 hasAuthorship W1969099992A5006834012 @default.
- W1969099992 hasAuthorship W1969099992A5049076723 @default.
- W1969099992 hasBestOaLocation W19690999921 @default.
- W1969099992 hasConcept C100299639 @default.
- W1969099992 hasConcept C104317684 @default.
- W1969099992 hasConcept C141231307 @default.
- W1969099992 hasConcept C153911025 @default.
- W1969099992 hasConcept C194993378 @default.
- W1969099992 hasConcept C34957205 @default.
- W1969099992 hasConcept C54355233 @default.
- W1969099992 hasConcept C67705224 @default.
- W1969099992 hasConcept C86803240 @default.
- W1969099992 hasConceptScore W1969099992C100299639 @default.
- W1969099992 hasConceptScore W1969099992C104317684 @default.
- W1969099992 hasConceptScore W1969099992C141231307 @default.
- W1969099992 hasConceptScore W1969099992C153911025 @default.
- W1969099992 hasConceptScore W1969099992C194993378 @default.
- W1969099992 hasConceptScore W1969099992C34957205 @default.
- W1969099992 hasConceptScore W1969099992C54355233 @default.
- W1969099992 hasConceptScore W1969099992C67705224 @default.
- W1969099992 hasConceptScore W1969099992C86803240 @default.
- W1969099992 hasIssue "5" @default.
- W1969099992 hasLocation W19690999921 @default.
- W1969099992 hasLocation W19690999922 @default.
- W1969099992 hasLocation W19690999923 @default.
- W1969099992 hasOpenAccess W1969099992 @default.
- W1969099992 hasPrimaryLocation W19690999921 @default.
- W1969099992 hasRelatedWork W1854602420 @default.
- W1969099992 hasRelatedWork W2069184423 @default.
- W1969099992 hasRelatedWork W2090467184 @default.
- W1969099992 hasRelatedWork W2150113817 @default.
- W1969099992 hasRelatedWork W2351821092 @default.
- W1969099992 hasRelatedWork W2518774397 @default.
- W1969099992 hasRelatedWork W2982424918 @default.
- W1969099992 hasRelatedWork W3013628298 @default.
- W1969099992 hasRelatedWork W4232239547 @default.
- W1969099992 hasRelatedWork W2187207551 @default.
- W1969099992 hasVolume "22" @default.
- W1969099992 isParatext "false" @default.
- W1969099992 isRetracted "false" @default.
- W1969099992 magId "1969099992" @default.
- W1969099992 workType "article" @default.