FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969118462> ?p ?o ?g. }

• W1969118462 endingPage "327" @default.
• W1969118462 startingPage "322" @default.
• W1969118462 abstract "Abstract— A recent study has shown that N‐acetylcysteine (NAC) not only has sun‐protective properties but also inhibits the UVB‐induced suppression of contact hypersensitivity (CHS) in mice. Because NAC does not absorb any UVA (320‐400 nm radiation) or UVB (290‐320 nm radiation) we have studied the underlying mechanism of protection. Irradiation of solutions of plasmid DNA with UVC (200‐290 nm radiation) (10 J m‐2) resulted in the formation of cyclobutane pyrimidine dimers, but the extent to which this occurred was not affected by the presence of NAC as was determined by an in vitro T4 endonuclease assay. N‐acetylcysteine proved not to have any effect on the photoisomerization of trans‐urocanic acid (UCA) to its cis‐form in vitro; at equilibrium, approximately 55% cis‐UCA was formed. The same percentage was also found in vivo on exposure of mice to UVB (15 kj m‐2). Topical application of NAC 30 min prior to irradiation did not have any influence as well on the photoisomerization of trans‐ to cis‐UCA. These in vivo experiments were performed under the same conditions used previously to show the protective effect of NAC against UVB‐induced suppression of CHS. We conclude that this protection of NAC is at least partly based on interference in the role of cis ‐UCA in UVB‐induced suppression of CHS. This conclusion is supported by the observation that NAC completely inhibits the suppression of CHS by cis ‐UCA administered to mice that were always kept in the dark. In the same range of doses as used in the present study, it was shown in our previous study that NAC alone does not affect the CHS response." @default.
• W1969118462 created "2016-06-24" @default.
• W1969118462 creator A5012240445 @default.
• W1969118462 creator A5035955413 @default.
• W1969118462 date "1996-03-01" @default.
• W1969118462 modified "2023-10-15" @default.
• W1969118462 title "The Protective Effect of N‐Acetylcysteine on UVB‐Induced Immunosuppression by Inhibition of the Action of Cis‐Urocanic Acid" @default.
• W1969118462 cites W1501422633 @default.
• W1969118462 cites W1563587102 @default.
• W1969118462 cites W1563599535 @default.
• W1969118462 cites W1591414362 @default.
• W1969118462 cites W1796759324 @default.
• W1969118462 cites W1808321390 @default.
• W1969118462 cites W1966875481 @default.
• W1969118462 cites W1971240868 @default.
• W1969118462 cites W1979950610 @default.
• W1969118462 cites W1989280230 @default.
• W1969118462 cites W1994586218 @default.
• W1969118462 cites W1998267570 @default.
• W1969118462 cites W1998360078 @default.
• W1969118462 cites W1998778722 @default.
• W1969118462 cites W2004288872 @default.
• W1969118462 cites W2005817830 @default.
• W1969118462 cites W2007666423 @default.
• W1969118462 cites W2018172250 @default.
• W1969118462 cites W2038821905 @default.
• W1969118462 cites W2042481280 @default.
• W1969118462 cites W2047047232 @default.
• W1969118462 cites W2048204505 @default.
• W1969118462 cites W2048988239 @default.
• W1969118462 cites W2063200382 @default.
• W1969118462 cites W2066643813 @default.
• W1969118462 cites W2071095297 @default.
• W1969118462 cites W2072048493 @default.
• W1969118462 cites W2072083337 @default.
• W1969118462 cites W2079396957 @default.
• W1969118462 cites W2091764628 @default.
• W1969118462 cites W2094619795 @default.
• W1969118462 cites W2118671268 @default.
• W1969118462 cites W2128692190 @default.
• W1969118462 cites W2149203688 @default.
• W1969118462 cites W2150289849 @default.
• W1969118462 cites W2196173206 @default.
• W1969118462 cites W2405649575 @default.
• W1969118462 cites W2580854617 @default.
• W1969118462 cites W4235729249 @default.
• W1969118462 cites W67186739 @default.
• W1969118462 doi "https://doi.org/10.1111/j.1751-1097.1996.tb03034.x" @default.
• W1969118462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8881338" @default.
• W1969118462 hasPublicationYear "1996" @default.
• W1969118462 type Work @default.
• W1969118462 sameAs 1969118462 @default.
• W1969118462 citedByCount "23" @default.
• W1969118462 countsByYear W19691184622019 @default.
• W1969118462 crossrefType "journal-article" @default.
• W1969118462 hasAuthorship W1969118462A5012240445 @default.
• W1969118462 hasAuthorship W1969118462A5035955413 @default.
• W1969118462 hasConcept C126661725 @default.
• W1969118462 hasConcept C143425029 @default.
• W1969118462 hasConcept C153911025 @default.
• W1969118462 hasConcept C161790260 @default.
• W1969118462 hasConcept C167975912 @default.
• W1969118462 hasConcept C181199279 @default.
• W1969118462 hasConcept C185592680 @default.
• W1969118462 hasConcept C202751555 @default.
• W1969118462 hasConcept C207001950 @default.
• W1969118462 hasConcept C2776381347 @default.
• W1969118462 hasConcept C2777847592 @default.
• W1969118462 hasConcept C2778004101 @default.
• W1969118462 hasConcept C2778460671 @default.
• W1969118462 hasConcept C54355233 @default.
• W1969118462 hasConcept C552990157 @default.
• W1969118462 hasConcept C55493867 @default.
• W1969118462 hasConcept C85311670 @default.
• W1969118462 hasConcept C86803240 @default.
• W1969118462 hasConceptScore W1969118462C126661725 @default.
• W1969118462 hasConceptScore W1969118462C143425029 @default.
• W1969118462 hasConceptScore W1969118462C153911025 @default.
• W1969118462 hasConceptScore W1969118462C161790260 @default.
• W1969118462 hasConceptScore W1969118462C167975912 @default.
• W1969118462 hasConceptScore W1969118462C181199279 @default.
• W1969118462 hasConceptScore W1969118462C185592680 @default.
• W1969118462 hasConceptScore W1969118462C202751555 @default.
• W1969118462 hasConceptScore W1969118462C207001950 @default.
• W1969118462 hasConceptScore W1969118462C2776381347 @default.
• W1969118462 hasConceptScore W1969118462C2777847592 @default.
• W1969118462 hasConceptScore W1969118462C2778004101 @default.
• W1969118462 hasConceptScore W1969118462C2778460671 @default.
• W1969118462 hasConceptScore W1969118462C54355233 @default.
• W1969118462 hasConceptScore W1969118462C552990157 @default.
• W1969118462 hasConceptScore W1969118462C55493867 @default.
• W1969118462 hasConceptScore W1969118462C85311670 @default.
• W1969118462 hasConceptScore W1969118462C86803240 @default.
• W1969118462 hasIssue "3" @default.
• W1969118462 hasLocation W19691184621 @default.
• W1969118462 hasLocation W19691184622 @default.
• W1969118462 hasOpenAccess W1969118462 @default.
• W1969118462 hasPrimaryLocation W19691184621 @default.

• next