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- W1969202014 abstract "Objectives. We used intraluminal ultrasound imaging to provide additional information about the vascular pathology in Williams syndrome. Background. The cardiovascular pathology of Williams syndrome consists of medial hypertrophy in both systemic and pulmonary arteries, which results in lumen narrowing. Methods. Systemic and pulmonary arteries were examined in vivo using intravascular ultrasound imaging (5F, 30-MHz catheter) in three children with Williams syndrome. Results. All arteries exhibited severe wall thickening with secondary lumen narrowing. Balloon dilations of a branch pulmonary artery in two children resulted in a significant localized increase in lumen caliber associated with a tear is the vessel wall. Conclusions. lntravascular ultrasound imaging in patients with Williams syndrome may permit better understanding of the pathophysiology of the syndrome and a more rational approach to therapeutic interventions." @default.
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- W1969202014 date "1993-06-01" @default.
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- W1969202014 title "Generalized arteriopathy in williams syndrome: An intravascular ultrasound study" @default.
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- W1969202014 doi "https://doi.org/10.1016/0735-1097(93)90394-g" @default.
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