Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969220025> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1969220025 endingPage "16" @default.
- W1969220025 startingPage "7" @default.
- W1969220025 abstract "Staphylococcal α-toxin spreads readily as a film on aqueous media; the film contains 3 and 30 times as much protein as in films of mitochondrial structural protein and in a protein monolayer, respetively. The toxin forms a film also by adsorption from the hypophase. The ability of α-toxin both to spread and adsorb at the air-water interface is increased markedly by 6 M urea. Penetration of α-toxin into lipid monolayers is influenced greatly by the chemical structure of the lipid; the ΔΠ values are in the order cholesterol > phosphatidyl choline > phosphatidyl inositol > sphingomyelin > ganglioside. In line with the known binding of gangliosides by histones, penetration of the basic toxin into the air-water interface is inhibited by ganglioside as well as by sulfatide monolayers. Inasmuch as film penetration (ΔΠ) is consistent with anchoring of the protein at the interface, binding of the cationic toxin under the negatively charged monolayers of phosphatidyl inositol, sulfatide, or ganglioside explains the low ΔΠ values observed with these lipids and the known ability of this protein to coat the host membrane. Penetration of α-toxin into lecithin monolayers increases as the protein concentration in the hypophase becomes greater, as the initial pressure of the lipid film becomes smaller, as pH or temperature of hypophase increases." @default.
- W1969220025 created "2016-06-24" @default.
- W1969220025 creator A5050058807 @default.
- W1969220025 creator A5075425702 @default.
- W1969220025 date "1971-03-01" @default.
- W1969220025 modified "2023-10-01" @default.
- W1969220025 title "Lipid monolayers. Interactions with staphylococcal α-toxin" @default.
- W1969220025 cites W106026948 @default.
- W1969220025 cites W1555810311 @default.
- W1969220025 cites W1582289324 @default.
- W1969220025 cites W1800074394 @default.
- W1969220025 cites W1973213585 @default.
- W1969220025 cites W1991516777 @default.
- W1969220025 cites W1995387814 @default.
- W1969220025 cites W2009364378 @default.
- W1969220025 cites W2019351451 @default.
- W1969220025 cites W2021672226 @default.
- W1969220025 cites W2036257465 @default.
- W1969220025 cites W2052947734 @default.
- W1969220025 cites W2071642937 @default.
- W1969220025 cites W2072180168 @default.
- W1969220025 cites W2092049033 @default.
- W1969220025 cites W2100976929 @default.
- W1969220025 cites W2132338075 @default.
- W1969220025 cites W2144336067 @default.
- W1969220025 cites W2270523344 @default.
- W1969220025 cites W2334200415 @default.
- W1969220025 cites W2339892242 @default.
- W1969220025 cites W2340500900 @default.
- W1969220025 cites W2419484854 @default.
- W1969220025 cites W2502927823 @default.
- W1969220025 doi "https://doi.org/10.1016/0005-2736(71)90352-x" @default.
- W1969220025 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4325423" @default.
- W1969220025 hasPublicationYear "1971" @default.
- W1969220025 type Work @default.
- W1969220025 sameAs 1969220025 @default.
- W1969220025 citedByCount "55" @default.
- W1969220025 countsByYear W19692200252018 @default.
- W1969220025 crossrefType "journal-article" @default.
- W1969220025 hasAuthorship W1969220025A5050058807 @default.
- W1969220025 hasAuthorship W1969220025A5075425702 @default.
- W1969220025 hasConcept C12554922 @default.
- W1969220025 hasConcept C127413603 @default.
- W1969220025 hasConcept C185592680 @default.
- W1969220025 hasConcept C2777331542 @default.
- W1969220025 hasConcept C2777367657 @default.
- W1969220025 hasConcept C41625074 @default.
- W1969220025 hasConcept C42475967 @default.
- W1969220025 hasConcept C55493867 @default.
- W1969220025 hasConcept C61322309 @default.
- W1969220025 hasConcept C7070889 @default.
- W1969220025 hasConcept C80107235 @default.
- W1969220025 hasConcept C86803240 @default.
- W1969220025 hasConceptScore W1969220025C12554922 @default.
- W1969220025 hasConceptScore W1969220025C127413603 @default.
- W1969220025 hasConceptScore W1969220025C185592680 @default.
- W1969220025 hasConceptScore W1969220025C2777331542 @default.
- W1969220025 hasConceptScore W1969220025C2777367657 @default.
- W1969220025 hasConceptScore W1969220025C41625074 @default.
- W1969220025 hasConceptScore W1969220025C42475967 @default.
- W1969220025 hasConceptScore W1969220025C55493867 @default.
- W1969220025 hasConceptScore W1969220025C61322309 @default.
- W1969220025 hasConceptScore W1969220025C7070889 @default.
- W1969220025 hasConceptScore W1969220025C80107235 @default.
- W1969220025 hasConceptScore W1969220025C86803240 @default.
- W1969220025 hasIssue "1" @default.
- W1969220025 hasLocation W19692200251 @default.
- W1969220025 hasLocation W19692200252 @default.
- W1969220025 hasOpenAccess W1969220025 @default.
- W1969220025 hasPrimaryLocation W19692200251 @default.
- W1969220025 hasRelatedWork W1797315357 @default.
- W1969220025 hasRelatedWork W1985777862 @default.
- W1969220025 hasRelatedWork W2010245048 @default.
- W1969220025 hasRelatedWork W2020812995 @default.
- W1969220025 hasRelatedWork W2059119688 @default.
- W1969220025 hasRelatedWork W2061886356 @default.
- W1969220025 hasRelatedWork W2075425490 @default.
- W1969220025 hasRelatedWork W2090279843 @default.
- W1969220025 hasRelatedWork W2126316011 @default.
- W1969220025 hasRelatedWork W1794867175 @default.
- W1969220025 hasVolume "233" @default.
- W1969220025 isParatext "false" @default.
- W1969220025 isRetracted "false" @default.
- W1969220025 magId "1969220025" @default.
- W1969220025 workType "article" @default.