FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1969234492> ?p ?o ?g. }

• W1969234492 endingPage "153" @default.
• W1969234492 startingPage "147" @default.
• W1969234492 abstract "Dogs are the main domestic reservoirs of L. (L.) chagasi. Once in the vertebrate host, the parasite may cause visceral leishmaniasis, which can also be transmitted to humans. Infected symptomatic dogs show disorganization in the white pulp in spleen tissue and a reduction in T lymphocytes in peripheral blood. To investigate whether apoptosis is involved in white pulp disorganization and diminished T cell counts in peripheral blood, apoptotic T cells from the spleen and peripheral blood of dogs naturally infected with L. (L.) chagasi and presenting clinical manifestations were quantified and compared with healthy dogs. Thirteen symptomatic adult dogs infected by L. (L.) chagasi and six healthy dogs from a nonendemic area (controls) were included in the study. Samples from spleen and peripheral blood were used to quantify apoptosis in CD3 lymphocytes by flow cytometry using Anexin V and Multicaspase kits; the results were compared using the Mann Whitney test. The percentage of total T cells was lower in Leishmania infected dogs compared to healthy controls (P<0.05). Apoptosis levels in T cells from PBMC and spleen were higher in infected dogs than in controls (P<0.05). The least squares method test was used to determine the effect between the degree of structural organization of spleen white pulp and the percentage of apoptosis in the spleen. A significant effect on the level of white pulp morphological disorganization and percentage of apoptosis in spleen T cells was observed (F=20.45; P=0.0014). These data suggest that apoptosis is an important for the immunopathogenesis of canine visceral leishmaniasis." @default.
• W1969234492 created "2016-06-24" @default.
• W1969234492 creator A5024137803 @default.
• W1969234492 creator A5061010319 @default.
• W1969234492 creator A5062141083 @default.
• W1969234492 creator A5074220859 @default.
• W1969234492 creator A5081832103 @default.
• W1969234492 creator A5083231407 @default.
• W1969234492 creator A5083641934 @default.
• W1969234492 date "2012-03-01" @default.
• W1969234492 modified "2023-10-17" @default.
• W1969234492 title "Apoptosis in T lymphocytes from spleen tissue and peripheral blood of L. (L.) chagasi naturally infected dogs" @default.
• W1969234492 cites W1222538688 @default.
• W1969234492 cites W1619437296 @default.
• W1969234492 cites W1920089213 @default.
• W1969234492 cites W1965035447 @default.
• W1969234492 cites W1974051529 @default.
• W1969234492 cites W1982904037 @default.
• W1969234492 cites W1984838539 @default.
• W1969234492 cites W1994521673 @default.
• W1969234492 cites W1997785635 @default.
• W1969234492 cites W2012307494 @default.
• W1969234492 cites W2014670846 @default.
• W1969234492 cites W2023632595 @default.
• W1969234492 cites W2031722631 @default.
• W1969234492 cites W2033935793 @default.
• W1969234492 cites W2034327730 @default.
• W1969234492 cites W2035787106 @default.
• W1969234492 cites W2062706116 @default.
• W1969234492 cites W2064246035 @default.
• W1969234492 cites W2066954635 @default.
• W1969234492 cites W2068592961 @default.
• W1969234492 cites W2069546240 @default.
• W1969234492 cites W2078532650 @default.
• W1969234492 cites W2078886897 @default.
• W1969234492 cites W2081087519 @default.
• W1969234492 cites W2088238276 @default.
• W1969234492 cites W2095610024 @default.
• W1969234492 cites W2098694347 @default.
• W1969234492 cites W2103574532 @default.
• W1969234492 cites W2125964922 @default.
• W1969234492 cites W2126917669 @default.
• W1969234492 cites W2140833102 @default.
• W1969234492 cites W2162027668 @default.
• W1969234492 cites W2164438387 @default.
• W1969234492 cites W2165091534 @default.
• W1969234492 cites W963534351 @default.
• W1969234492 doi "https://doi.org/10.1016/j.vetpar.2011.08.024" @default.
• W1969234492 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21899954" @default.
• W1969234492 hasPublicationYear "2012" @default.
• W1969234492 type Work @default.
• W1969234492 sameAs 1969234492 @default.
• W1969234492 citedByCount "40" @default.
• W1969234492 countsByYear W19692344922012 @default.
• W1969234492 countsByYear W19692344922013 @default.
• W1969234492 countsByYear W19692344922014 @default.
• W1969234492 countsByYear W19692344922015 @default.
• W1969234492 countsByYear W19692344922016 @default.
• W1969234492 countsByYear W19692344922017 @default.
• W1969234492 countsByYear W19692344922018 @default.
• W1969234492 countsByYear W19692344922019 @default.
• W1969234492 countsByYear W19692344922020 @default.
• W1969234492 countsByYear W19692344922021 @default.
• W1969234492 countsByYear W19692344922022 @default.
• W1969234492 countsByYear W19692344922023 @default.
• W1969234492 crossrefType "journal-article" @default.
• W1969234492 hasAuthorship W1969234492A5024137803 @default.
• W1969234492 hasAuthorship W1969234492A5061010319 @default.
• W1969234492 hasAuthorship W1969234492A5062141083 @default.
• W1969234492 hasAuthorship W1969234492A5074220859 @default.
• W1969234492 hasAuthorship W1969234492A5081832103 @default.
• W1969234492 hasAuthorship W1969234492A5083231407 @default.
• W1969234492 hasAuthorship W1969234492A5083641934 @default.
• W1969234492 hasBestOaLocation W19692344921 @default.
• W1969234492 hasConcept C137061746 @default.
• W1969234492 hasConcept C142724271 @default.
• W1969234492 hasConcept C190283241 @default.
• W1969234492 hasConcept C202751555 @default.
• W1969234492 hasConcept C203014093 @default.
• W1969234492 hasConcept C2776555147 @default.
• W1969234492 hasConcept C2777092883 @default.
• W1969234492 hasConcept C2778232189 @default.
• W1969234492 hasConcept C2778488018 @default.
• W1969234492 hasConcept C2778689377 @default.
• W1969234492 hasConcept C2780931953 @default.
• W1969234492 hasConcept C55493867 @default.
• W1969234492 hasConcept C71924100 @default.
• W1969234492 hasConcept C86803240 @default.
• W1969234492 hasConceptScore W1969234492C137061746 @default.
• W1969234492 hasConceptScore W1969234492C142724271 @default.
• W1969234492 hasConceptScore W1969234492C190283241 @default.
• W1969234492 hasConceptScore W1969234492C202751555 @default.
• W1969234492 hasConceptScore W1969234492C203014093 @default.
• W1969234492 hasConceptScore W1969234492C2776555147 @default.
• W1969234492 hasConceptScore W1969234492C2777092883 @default.
• W1969234492 hasConceptScore W1969234492C2778232189 @default.
• W1969234492 hasConceptScore W1969234492C2778488018 @default.
• W1969234492 hasConceptScore W1969234492C2778689377 @default.

• next