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• W1969253709 endingPage "535" @default.
• W1969253709 startingPage "527" @default.
• W1969253709 abstract "OBJECTIVE: The meningeal structure of the cavernous sinus (lateral sellar compartment) was anatomically and histologically studied. We discuss the clinical and surgical significance and present clinical examples of cranial base tumors. METHODS: Ten adult cadaveric heads were used for microsurgical dissection or histological studies. Specimens of the cavernous sinus were continuously sectioned in three dimensions and stained by Masson's trichrome method. The findings are anatomically discussed as they pertain to presented clinical cases. RESULTS: The cavernous sinus, located in an interdural space between periosteal and meningeal dura, is properly accessed by detachment of the periosteal bridge between the superior orbital fissure and the middle fossa. The lateral meningeal dura is dissected under minimal hemorrhage from the sinus, with a surgically important cleaving plane between the “deep layer,” a semitransparent meningeal sheath with which the cranial nerves are covered and protected. It has various degrees of meningeal pockets, of which Meckel's cave is the largest example. Adventitia of the carotid artery in the sinus, uncovered with protective meninges, is considered to contact directly with tumors of the sinus origin. The meningeal wall of the cavernous sinus anatomically has three weak points as far as tumor invasion and extension are concerned: the venous plexus around the superior orbital fissure, the loose texture of the medial wall around the pituitary body, and dural pockets of the IIIrd and Vth cranial nerves. The dural wall is extremely thin or missing at those points. CONCLUSION: A surgical technique based on the meningeal anatomy is important for cavernous sinus surgery. The cavernous apex and Meckel's cave, which are spaces of convergence of cranial nerves, however, are weak points for surgical dissection. The presence or absence of tumor invasion into those areas may influence the microsurgical results." @default.
• W1969253709 created "2016-06-24" @default.
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• W1969253709 date "1996-09-01" @default.
• W1969253709 modified "2023-10-08" @default.
• W1969253709 title "Meningeal Architecture of the Cavernous Sinus: Clinical and Surgical Implications" @default.
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• W1969253709 doi "https://doi.org/10.1097/00006123-199609000-00019" @default.
• W1969253709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8875483" @default.
• W1969253709 hasPublicationYear "1996" @default.
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